My updated metabolic map is less focused on substrate utilization and thresholds and more focused on metabolic stability. I believe the shift is subtle but important.
Instead of only asking:
“What fuel is being used?”
The model also asks:
“How stable is the metabolic system under stress?”
In this framework, lactate becomes the central proxy to understand the balance, drift, or overload of the metabolic system.
Approximate translation and comparison with different models:
• Zone 1 = low metabolic stress
Clearly below LT1/VT1
• Zone 2 = metabolic equilibrium
Near LT1/VT1, where lactate production and clearance remain tightly matched and the system operates at its highest sustainable balance
• Zones 3–4 = metabolic drift
The system progressively moves away from optimal mitochondrial matching capacity, even if lactate may still achieve a “steady state”…CP/MLSS/VT2/LT2/V4…
• Zone 5+ = metabolic overload
Above CP/MLSS/VT2/LT2/V4, where no true steady state is physiologically achievable
The key conceptual distinction:
A lactate steady state is not the same as optimal metabolic equilibrium.
The metabolic equilibrium ceiling is near LT1/VT1 and Zone 2.
The steady-state ceiling is CP/MLSS/VT2/LT2/V4.
Performance is ultimately defined by how long the body can preserve metabolic equilibrium.
We aren't going to mince words on this one. If your response to an editor adding a date to an article on Wookieepedia is to tell them you hope they and their pets die, you are not a Star Wars fan. Hate like that has no place here, and you are not welcome in our community.
Helldivers fans -- we’ve heard your feedback on the Helldivers 2 account linking update. The May 6 update, which would have required Steam and PlayStation Network account linking for new players and for current players beginning May 30, will not be moving forward.
We’re still learning what is best for PC players and your feedback has been invaluable. Thanks again for your continued support of Helldivers 2 and we’ll keep you updated on future plans.
“This piano is a 🇨🇳 CCP-free zone” — Brendan Kavanagh speaks out against China with Winnie the Pooh
Brendan returned to play the piano at St Pancras and made an impassioned speech today (Jan 26).
Brendan explains to the assembled crowd that he is holding Winnie the Pooh because the beloved character "has been banned by the CCP… this shows the power of the arts to undermine authoritarianism."
https://t.co/LrWp9e18Zh
Amazing how so many of cyclists are mowed down every year by maniac drivers, but they only show up on popular X accounts when it can be used as an anti-liberal slant
An innocent man was murdered in cold blood while riding his bicycle. The killers joked about it on social media
Yet, where is the media outrage?
Now you begin to understand the lie.
You need to know about what’s happening in #Darfur right now.
And you need to ask: Where the hell is the UN Security Council?
📰 English: https://t.co/HrzE23M79F
📰 Français : https://t.co/RBuVOFtii9
📰 Español: https://t.co/GZQdWOOs08
🔊 Listen: https://t.co/MDpCWskUdq
Twitter has removed the China state-affiliated media tag. @elonmusk needs to explains this. Especially in light of the new Shanghai @Tesla factory. #china
The newly-released US Senate Committee report concludes that:
• China began developing COVID vaccines before revealing the outbreak.
• An "unintentional research-related incident" at the Wuhan Institute of Virology (WIV) is the cause.
See the full timeline it presents: 👇
For decades, Justice Clarence Thomas has secretly accepted luxury trips from a major Republican donor, newly obtained documents and interviews show.
The extent and frequency of these apparent gifts to Thomas has no known precedent in modern SCOTUS history... 🧵👇