Aaron E Lin

Postdoc, @bsadamson & @PlossLab labs, @Princeton. @DamonRunyon Fellow. PhD in Virology, @sabeti_lab, Harvard & Broad.

[Ann Cirincione @AnnCirincione]

Thrilled to see our work out in @naturemethods today! We applied prime editing to multiplexed dropout screens and benchmarked the tool’s ability to induce phenotypes when installing premature stop codons in essential genes.

[Sofi Quinodoz @sofiquinodoz]

Excited to share a new preprint!
(1)🔬The nucleolus is the most prominent nuclear condensate, with a fascinating multilayered liquid-like structure, and is the site of ribosome biogenesis. But how does this multiphase architecture form and function?
https://t.co/xKP9tGFFlQ

[Alexander Ploss @PlossLab]

Please check out our newest study led by our very own @KeithBerggren https://t.co/Oz650R2mmh
Many thanks to our brilliant collaborators at @RobSchwartzLab @Crittermechanic @KleinerLabRNA @PrincetonMolBio @NCStateVetMed @Princeton #liver #HBV #epitranscriptome #RNA

[Aaron E Lin @Aaron_E_Lin]

@katbarnett3 @NIAIDFunding Congrats Kat!!! Well deserved!!

[Dylan Kotliar @DKotliar]

We are so excited to share a project that started before my MD/PhD (over 10 years ago) and comes out today in @NatureMicrobiol titled “Genome-wide association study identifies variants associated with fatal outcome from Lassa fever” https://t.co/JFLbt76Xuh

[Sergio Triana @shtriana]

We are thrilled to present our work delving into the molecular basis of Ebola virus disease across time! We established an extensive viral genomic and host transcriptomic dataset from a natural history study of 21 NHPs exposed to a lethal dose of EBOV. https://t.co/IBe7qddGc2

[Aaron E Lin @Aaron_E_Lin]

@NeuroLuebbert @PardisSabeti @RobertEdgarPhD @RNA_Life @DKotliar And @LisaEHensley1 too!

Actually, many folks in @sabeti_lab just published a follow-up study with bulk RNA-Seq for a dozen tissue samples from the same animals — would be SUPER cool to see if there’s similar viral seqs in tissues https://t.co/0RweBKM1X2

[Sergio Triana @shtriana]

We are thrilled to present our work delving into the molecular basis of Ebola virus disease across time! We established an extensive viral genomic and host transcriptomic dataset from a natural history study of 21 NHPs exposed to a lethal dose of EBOV. https://t.co/IBe7qddGc2

[Aaron E Lin @Aaron_E_Lin]

@NeuroLuebbert @PardisSabeti @RobertEdgarPhD @RNA_Life Phenomenal work, I’m excited to read the preprint in more detail this weekend! Glad @DKotliar and I could be of assistance!

[Laura Luebbert, PhD @NeuroLuebbert]

We expanded kallisto to translated alignment (nucleotides <-> amino acids), and used it to detect novel viruses in RNA seq data. The single-cell resolution allowed us to determine whether the presence of these viruses affected host gene expression. 🧵

https://t.co/d76fumgcbX

[Princeton University @Princeton]

More like the Guardin' State! 🧡 🖤

Congratulations to @PrincetonMBB who moves on to the Sweet 16 after a 78-63 victory over Mizzou!

Go Tigers! #MarchMadness

[@sabrina-solley.bsky.social @sabrina_solley]

@bsadamson lab Halloween- CRISPR edition! 🧬

[Britt Adamson @bsadamson]

Our group is looking for postdocs and a lab manager/research specialist! Come join us!

Research Specialist I/II: https://t.co/ECSMZril9j

Postdoctoral Research Associate:
https://t.co/yZj1gO8749

https://t.co/Me2iKoltfG

[Bill Gates @BillGates]

.@PardisSabeti is working to detect pathogens earlier and stop pandemics in the their tracks.

[Ivan Specht @ivan_specht]

We show how #OperationOutbreak (@OOeducation) can help assess the risk of pathogenic threats and provide epidemiological data useful to outbreak mitigation. A thread on our modeling paper with @Ivan_Specht @KianSani @TechnologyBryn @codeanticode @PardisSabeti and many others.

[Kim Lagerborg @KimLagerborg]

Honored to be featured as one of the #FacesOfCell @CellCellPress

[Nicole Welch @NicoleLWelch]

The mCARMEN Accelerated Article Preview is live on Nature Medicine!! (with data tracking the Omicron wave!) Check it out ⬇️

https://t.co/8m4N2wIUYN

[Marta Melé @marta_mele_m]

So proud to share our work “In vivo single-cell profiling of lncRNAs during Ebola virus infection” https://t.co/baAq6qdnRX Thanks to an amazing team: @santusluisa @RaquelGarcaPrez @mariasopenarios @Aaron_E_Lin @PardisSabeti and collaborators @broadinstitute @NIAID_NIH @BSC_CNS

[sabeti_lab @sabeti_lab]

Happy Holidays from Sabeti Land! Wishing you countless moments of joy and light throughout 2022!

[Nicole Welch @NicoleLWelch]

Excited to share our new preprint on mCARMEN! A highly multiplexed diagnostic platform to detect multiple respiratory viruses and variants including the new SARS-CoV-2 variant lineage, Omicron. ⬇️

https://t.co/SBzEBKtZ02

Collab w/ @sabeti_lab @cambearon @CDCgov @mgh_id @DARPA

[Kim Lagerborg @KimLagerborg]

Excited to share our newest publication “Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows”. Out in Nature Microbiology today!
(1)
https://t.co/VCOdb8cWgP