AML Physician Scientist, Director of the#BloomfieldCenter @OSUCCC. Working to overcome inequities in cancer care. #ASH-DEI/PrecisionMed. Science&Sparkling.
Congrats to Miles lab trainee Megan Bones on receiving an @ASH_hematology Graduate Hematology Award! So incredibly proud of you!!
Thank you to @ASH_hematology for the impactful support. Congrats to Julie and the rest of the ASH awardees!
Signaling mutations negate the favorable impact of NPM1 in older patients with AML treated with HMA/VEN. Just out in @AjHematology. Another great collaboration! @madanatyazan@beatalleukemia@AkEisfeld@LeukDocJZ and many others!
https://t.co/ccradbEAkO
Respiratory failure is a leading cause of death in AML.
It begins when leukemia infiltrates the lung. Almost nothing was known about what happens locally.
We looked.
🧵 @NatImmunol
🔗 https://t.co/OkhyRTRN4F
🚨 Excited to share our new Nature Immunology @NatImmunol paper! 🫁
How does acute myeloid #leukemia hijack the #lung and trigger #respiratory failure?
We found #AML cells drive #pulmonary remodeling via Galectin-9 & IL-33 signaling. And we identified drug treatments that can reverse it! 💊
Huge thanks to an amazing teamwork co-led with @iannisaifantis1@VarvaraParask@nyugrossman
https://t.co/otxrK7d0Cq
📅 Mark Your Calendars!
The Hematologic Malignancies Conference is back for its second series!
🗓️ 01–04 November 2027
📍 Playa Mujeres, Mexico
Join leading PI's for an inspiring 4 day conference programme full of cutting edge science, meaningful discussions, and valuable networking opportunites.
🔔 Don't miss out! Sign up for updates and be the first to know when registration opens: https://t.co/xb1445PCBI
#FusionCancerResearch #FusionStemCells #FusionHumanDisease
Excited to share our study on immune interactions in extramedullary (lung) acute myeloid leukemia (AML) out today at @NatImmunol !! Acute respiratory failure frequently occurs in AML due to leukemia infiltration of the lungs. The question is why and what can we do to suppress it. @VarvaraParask in the lab started this work by mapping AML:stromal and AML:immune cell interactions using scRNA-Seq and Visium/Xenium @10xGenomics spatial tools.
https://t.co/96RB7muFZK
Many congratulations to this distinguished group of awardees , esp to @mkonople who is a role model for many of us in this field & has done so much to improve our understanding of AML biology & brought novel therapeutic options from the benchside to to clinic.
Go Marina 👏🏼💪🏻
A blood cancer can be a devastating diagnosis, but thanks to world-leading expertise at @OSUCCC_James, we’re working to be able to deliver the best treatment to every individual patient, every time. In this new “Pass the Mic,” Dr. Ann-Kathrin Eisfeld talks about how she and her colleagues are staying on the cutting edge in researching and treating rare leukemias and other blood disorders – and ultimately creating hope for patients and their loved ones.
A reminder to think outside of the box when evaluating AML genomics- overlooking or not testing is consequential for our patients! Done with the best friends and collaborators @lindemilesphd@sanamloghavi@OSUHematology@OSUCCC_James
Just out in @LeukemiaJnl 📣
With all hype around #RAS , We thought it’d be cool to characterize BRAF mutations in AML… led by the best collaborators in the business @lindemilesphd@AkEisfeld & teams
https://t.co/zJbcWLhcSO
Non-canonical BRAF mutations in AML: underappreciated, enriched in AML-MR,..and maybe a therapeutic opportunity? Most importantly, a reminder to think outside of the box when evaluating AML genomics. Done with the best friends and collaborators @lindemilesphd@sanamloghavi
Non-canonical BRAF mutations in AML: underappreciated, enriched in AML-MR,..and maybe a therapeutic opportunity? Most importantly, a reminder to think outside of the box when evaluating AML genomics. Done with the best friends and collaborators @lindemilesphd@sanamloghavi
🔴~1% of AML cases harbor BRAF mutations (canonical & non-canonical); mostly outside V600 hotspot & enriched in myelodysplasia-related AML (AML-MR)
Just out in @LeukemiaJnl 📣
With all hype around #RAS , We thought it’d be cool to characterize BRAF mutations in AML… led by the best collaborators in the business @lindemilesphd@AkEisfeld & teams
https://t.co/zJbcWLhcSO
Honored to deliver a commencement address to the outstanding graduates at @cityofhope - the future is ready for you! Share your stories and let’s engage every person in building the next era in which we end cancer, together!
Super proud of @beatalleukemia for delivering a fantastic presentation of the OPTI-AML data showing that Aza/Ven-14 is NOT equivalent to Aza/Ven-28 days at least for induction cycles 1-2. Highly impactful study from our BEAT AML team @bcutd_research