Allen Frontiers

The Paul G. Allen Frontiers Group explores the landscape of bioscience and funds ideas at the frontier of knowledge to advance science & make the world better.

[Allen Frontiers @AllenFrontiers]

A new technique dubbed seqFISH, developed by Long Cai, a researcher at our Allen Discovery Center for Cell Lineage Tracing @UWMedicine , enables scientists to image 10,421 genes at once within individual cells. https://t.co/Y9wCBs0QDB

[UW Medicine Newsroom @uwmnewsroom]

Today in Science magazine's First Release section: DNA accessibility and gene expression are jointly profiled in thousands of single cells through new co-assay @sciencemagazine @BrotmanBaty @AllenFrontiers @uwgenome @TheNobleDust @JShendure @coletrapnell https://t.co/BEigiR8G9p

[allen institute @AllenInstitute]

Explore the power of #optogenetics with leading scientists including our Next Generation Council Member @VivianGradinaru and Allen Distinguished Investigator @eboyden3 in a #SfNvirtual conference on September 20.

[Allen Frontiers @AllenFrontiers]

Recent data from a ~90,000-year-old teenager showed that she had a Neanderthal mom and Denisovan dad. Researchers had long suspected that these two groups of ancient human relatives interbred, but no one found a direct offspring until recently.

https://t.co/PO3W8XzUkZ

[Allen Frontiers @AllenFrontiers]

Ancient #DNA shows that humans not only mated with Neanderthals but also Denisovans, & Denisovans & Neanderthals with each other. "It’s an amazing, lucky thing to find this," says David Reich from our Allen Discovery Center @BostonChildrens & @harvardmed. https://t.co/3G7MiNrquE

[Allen Frontiers @AllenFrontiers]

.@drmichaellevin, director of our Allen Discovery Center at @TuftsUniversity, imagines one day using #bioelectricity to reverse birth defects in the womb, treat #cancer, or even grow new limbs on amputees. Learn more about his current research.
https://t.co/j517l3uCOY

[Allen Frontiers @AllenFrontiers]

Congratulations to Allen Distinguished Investigator Anthony Zador for recognition as a Gill Symposium Transformative Investigator for his work developing a revolutionary brain mapping method.

https://t.co/VrSzStynd1

[Allen Frontiers @AllenFrontiers]

ICYMI: Recent research by Allen Distinguished Investigator Steve Horvath and his colleagues challenges the notion that one can stop aging by maintaining longer telomeres.
https://t.co/mVmuBJs0Kr

[Allen Frontiers @AllenFrontiers]

Recent findings suggest that mutations in the HNRNPU gene lead to a syndrome characterized by intellectual disability, and seizures. Allen Distinguished Investigator Evan Eichler's team is investigating how the mutations can contribute to #autism.
https://t.co/htU5VlUNtb

[Allen Frontiers @AllenFrontiers]

Our Allen Discovery Centers respond to worldwide community enthusiasm for a right-sized, risk-tolerant mechanism to support scientific exploration.

Learn more: https://t.co/EHziUiUNUi

[Walter Neary @wtneary]

Important because we can look into the mouse at the cellular level & see ourselves: mouse genome further mapped by scientists @JShendure @coletrapnell @cusanovich @ahill_tweets of @uwmedicine @uwgenome @AllenFrontiers @BrotmanBaty https://t.co/ZsCvJfYcOA via @CellCellPress

[Allen Frontiers @AllenFrontiers]

.@JShendure & colleagues at our Allen Discovery Center for Cell Lineage Tracing mapped the regulatory landscape of the mouse genome at a single-cell resolution. These data could help advance the understanding of tissue development & how diseases take hold.
https://t.co/koZIRJ8lPv

[Allen Frontiers @AllenFrontiers]

A group of German researchers have used light to make deaf gerbils hear using #optogenetics, a recently developed technology pioneered by Allen Distinguished Investigators Ed Boyden, and Feng Zhang, Ph.D.
https://t.co/cyWvAAX5zg

[Ed Boyden @eboyden3]

Combining expansion microscopy and lattice light sheet microscopy enables nanoscopy at mouse-cortical-thickness and whole-fly-brain scale. Some images of mouse cortex dendritic spines from the biorxiv preprint (https://t.co/iYLozAsVFm).

[Allen Frontiers @AllenFrontiers]

A team led by Allen Distinguished Investigator Ralf Jungmann recently succeeded in imaging actin networks in cells in greater detail than before using modes of microscopy that can resolve cellular structures with dimensions on the order of nanometers.

https://t.co/rRVdSRsXzj

[Allen Frontiers @AllenFrontiers]

Interesting study by Stanislav Shvartsman, a PI at our Allen Discovery Center @TuftsUniversity, and his colleagues.

[Allen Frontiers @AllenFrontiers]

“It’s humbling to think that this function had been hiding in plain sight for all these years.” Research by K.C. Huang, a researcher at our Allen Discovery Center at Stanford University, and his colleagues reveals new insights about E. coli's defenses.
https://t.co/YWvkEUf5F3

[Allen Frontiers @AllenFrontiers]

A recent discovery could point to a new way to develop #antibiotics. K.C. Huang, a researcher at our Allen Discovery Center @Stanford, and his colleagues found that the outer layer of #Ecoli behaves very differently than scientists had previously believed.
https://t.co/Y48kT7awxE

[Allen Frontiers @AllenFrontiers]

“Brains are great, but we have to remember where they came from. Neurons evolved from nonneural cells..." @drmichaellevin, director for our Allen Discovery Center @TuftsUniversity, weighs in on research to investigate slime mold's ability to learn.
https://t.co/kWGraZSxcf

[Allen Frontiers @AllenFrontiers]

Now that researchers including Jessica Whited, a PI at our Allen Discovery Center @TuftsUniversity, have the whole axolotl genome, they’re hoping to unlock secrets of regeneration and perhaps even to learn how humans could harness this power for ourselves.
https://t.co/YpVQXWdWsz