Amir Englund

Cannabis scientist at the Institute of Psychiatry, King's College London

[Amir Englund @AmirEnglund]

🚨🚨New paper out🚨🚨
Published today in @npp_journal we explored the effects of vaporised cannabis with these CBD:THC ratios – 0:1, 1:1, 2:1, 3:1 in healthy volunteers. ⬇️🧵

@KingsIoPPN @The_MRC #cannabis #CBD #THC

https://t.co/225N9y9XpX

[Addiction Journal @AddictionJrnl]

Associations between modes of cannabis use and cannabis use disorder: Evidence from the 2022 to 2023 United States National Survey on Drug Use and Health https://t.co/STAzPoc8bc

[Amir Englund @AmirEnglund]

@TaimazGhaffari You can't handle my studie!

[Amir Englund @AmirEnglund]

Placebo-controlled trial of high dose (800mg/day) CBD for neuropathic pain finds a small improvement (14%) in pain scores compared to placebo. CBD had no benefits to sleep, anxiety or depression, with very mild side-effects.

https://t.co/XA305beHV3

[Taimaz Ghaffari @TaimazGhaffari]

🚨🎙️ Mitt i en växande protestvåg mot AI i USA och den globala AI-kapplöpningen publicerar påve Leo en encyklika – ett försvar för mänskligheten i mötet med tekniken.

[Amir Englund @AmirEnglund]

New paper out 🚨
Strength of Danish hash has increased by almost 4x in 20yrs - and associated with cannabis related harms

https://t.co/EHU6bzwDv6

[Neuropsychopharmacology @npp_journal]

In a longitudinal study, the authors link cannabis use to blunted reward anticipation signaling, a neural pattern associated with addiction and anhedonia 🧠 / @m_wall @Will_Lawn

https://t.co/6jFQHeusyu

[Cannabis and Cannabinoid Research Journal @CannabisJrnl]

🌿 4/20 check: The "entourage effect" — whole cannabis > sum of its parts — is one of the plant's biggest claims. A new scoping review says the evidence is surprisingly thin. More hypothesis than hard science.

📄 https://t.co/jRdjBGGqbE

#EntourageEffect #CannabisScience #420

[Cannabis and Cannabinoid Research Journal @CannabisJrnl]

🏃 New pilot study: regular cannabis users had blunted anandamide responses after exercise — plus worse mood & more pain than non-users. Implications for withdrawal & cannabis use disorder.

📄 https://t.co/Ei672ioJ7l

#CannabisResearch #RunnerHigh

[Dom Oliver @Dom__Oliver]

🚨 New preprint: Can LLMs help assess psychosis risk from clinical interviews?

Early detection is key—but current approaches rely on specialist interpretation, limiting scalability.

We tested whether open-weight LLMs can help 🧵👇

[Taimaz Ghaffari @TaimazGhaffari]

Det är crunch week. Trump skickar trupper till Mellanöstern för att ”hålla alla valmöjligheter öppna”.

Samtidigt försöker de regionala länderna göra allt för att inleda samtal för att avsluta kriget.

Militärstrateger och geopolitiska analytiker menar att Trump nu har försatt sig i ett läge med två val – båda dåliga.

Jag skriver mer om det i min senaste text på Substack >>>

[Amir Englund @AmirEnglund]

@SkumlienMartine

[Neuropsychopharmacology @npp_journal]

#TWiNPP

In a longitudinal study, Skumlien et al. link cannabis use to blunted reward anticipation signaling, a neural pattern associated with addiction and anhedonia 🧠 / @m_wall @Will_Lawn

https://t.co/6jFQHev0o2

[Janni Leung @jannileung]

New ICPS study found many Australians are using medicinal cannabis for conditions that do not have strong evidence for.

Congratulations Dani Dawson for leading this important work

https://t.co/HBAzzaiU8o

[Dr. Justin (he/they) 🏳️‍🌈 is moving to blue sky @justinrmatheson]

New from our team at CAMH - we find nuanced evidence for next-day performance effects of smoked cannabis, likely associated with higher-THC-potency products https://t.co/CYaYDJ8FBl

[Amir Englund @AmirEnglund]

@petterkar1sson Tycker lite kontext saknas här.
Typ som att omvandla "NRT reducerar tobaksbruk" till "nikotinbruk reducerar nikotinbruk".
Form, administrationssätt och dos spelar roll.

[Cannabis and Cannabinoid Research Journal @CannabisJrnl]

⚖️ CBD for endometriosis pain?

In a triple-blind RCT, CBD oil was not better than placebo for postoperative chronic pelvic pain. Both groups improved, but CBD had more mild side effects.

A reminder of why rigorous trials matter.

📄 https://t.co/QekbzEOrMm

#Endometriosis #CBD

[Janni Leung @jannileung]

A systematic review and network meta-analysis compared the effectiveness of nicotine e-cigarettes with nicotine replacement therapies and control conditions for smoking cessation. #NCYSUR. Access paper here: https://t.co/vK4WfAot1V

[Will Lawn @Will_Lawn]

First longitudinal MRI paper from our CannTeen study (n=96) shows that over 1-yr #cannabis use is associated with reductions in activity in the v-str when anticipating money #reward. Congrats to @SkumlienMartine lead author and the whole CannTeam. https://t.co/JKsOq1q6nR

[Addiction Journal @AddictionJrnl]

A systematic review and meta-analysis of self-reported exposure to cannabis advertising and its association with cannabis use and intentions https://t.co/zte0gfMRii