Arnon Lab

Based at @KirOxford deciphering lymphocyte trafficking and B resident memory cells in lungs and spleen / Account ran by lab members.

[Arnon Lab @ArnonGroup]

Check out our recent publication on how an influenza #rechallenge triggers Brm cell migration and relocation to boost antibody secretion at infected sites! https://t.co/jDl2PijZLa

[Arnon Lab @ArnonGroup]

For this week’s journal club we went rogue and sat in a nice Italian cafe! And guess what? Anti-PD-1 therapy doesn't just target tumors! It also boosts T cell responses in lymph nodes, enhancing the fight against cancer from multiple fronts💪 @JExpMed

https://t.co/pqMuluGUhh

[Journal of Experimental Medicine @JExpMed]

Our July issue is out! https://t.co/sSnexUFTcf
The image shows thick sections of lungs of BAT mice reinfected with influenza and depleted for CD4+ T cells, showing the positioning of alveoli-associated plasma cells. By MacLean et al. @ArnonGroup (https://t.co/cZCzUBSa3a).

[Arnon Lab @ArnonGroup]

Our image of a flu-infected mouse lung from our latest publication made it to @JExpMed cover! Take a look at this thread by @lopes_bonifacio if curious about our main findings #residentmemory #flu #Bcells

[João Bonifacio Lopes @lopes_bonifacio]

Our lab most recent publication put forward the hypothesis of a population of resident memory B cells in the lung acting as ‘Guardians of the alveoli’. What does that mean and what is the evidence we have so far? A 🧵1/14 https://t.co/3KjSnPkkJR

[Arnon Lab @ArnonGroup]

Kicking off summer Journal club meetings discussing a recent publication by Becattini lab! “Local antigen encounter promotes generation of tissue-resident memory T cells in the large intestine” @MucosalImmunol
https://t.co/1r6L3qmQG2

[Arnon Lab @ArnonGroup]

This one is definitely a ‘Phage’ turner! @harrison_oj lab used phage display screening to identify antigen-specific BCRs in mLN and PPs & used tetramer stain to track these cells! A much-needed advance in the field to fish specific B cell clones and study them in depth #Immunity

[Immunity @ImmunityCP]

Online now: Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers https://t.co/uV2gozmgHe

[João Bonifacio Lopes @lopes_bonifacio]

It’s out!! Great story started by Andrew MacLean in which I had the chance to contribute and finish during my first year in @ArnonGroup

[Ivan Zanoni @Lo_Zanzi]

#LocationLocationLocation & #Interferons! @ArnonGroup @Tal_Arnon_Lab &co show @JExpMed that upon secondary influenza infections, #NKcell IFNg recruits tissue #memoryBcells to the infection focus where innate stimuli drive antibodies independently of #CD4T! https://t.co/GPnLxhmHpX

[De Giovanni Lab @MarcoDegiov89]

It was great pleasure to give a talk in such an amazing environment! Thanks @Tal_Arnon_Lab for inviting me and giving me a chance to share our work. And thanks so much to the IT that quickly solved the technical problems!

[Arnon Lab @ArnonGroup]

🥇 Journal club of 2024, 🥇pre-print in feat. Arnon’s Journal club +🥇Journal club of our new post-doc @nelaklim !🥳 fantastic concept on how a transcription factor can modulate B cells ‘recallability’ to antigen https://t.co/9h28FjYzkG

[Arnon Lab @ArnonGroup]

On top of a great presentation by #joannahfergusson on responses to adjuvants in human lymph node cultures, the bonus perk about @KirOxford internal seminars: pizza! 🍕

[Arnon Lab @ArnonGroup]

#tbt to our PhD student Sophia Oram presenting her findings at # in Sardinia! Exciting news about #PLTs in the #Spleen coming out soon! Well done Sophia!

[Kennedy Institute of Rheumatology @KirOxford]

We had a lovely sunny afternoon at the Kennedy Institute Summer Picnic on Friday! ☀️

Thanks to everyone who joined us, and to those who brought their families, children, and some VERY good dogs!

[Kennedy Institute of Rheumatology @KirOxford]

"The first 'recipes' for intestinal microbiome transfer date back to 4th Century China and were used as a cure for severe food poisoning!"

Thanks Kennedy researchers for sharing your favourite #microbiome facts for #WorldMicrobiomeDay!
@WMicrobiomeDay #Microbiomes4Life #WMD2023

[Arnon Lab @ArnonGroup]

Celebrating World Microbiome day at @KirOxford with puzzles and amazing bakes! Big shout to the Cold Room horrors cheesecakes 🍰🦠😋 #WMD2023 #scicomm @WMicrobiomeDay

[Arnon Lab @ArnonGroup]

Starting off the first Journal Club meeting in the @ArnonGroup with @lopes_bonifacio presenting a recent publication by @MatthewD_Park from @MiriamMerad Group! Brilliant science published in @NatImmunol 📝