Ayala Lab

We focus on understanding the molecular mechanisms that regulate the function of the RNA binding protein TDP-43 in health and disease

[ALS Network @youralsnetwork]

The @NIH announced cuts in grant funding, threatening vital research for neuromuscular diseases like ALS. While the policy is currently tied up in court, research funding remains at risk. @youralsnetwork and partners oppose these cuts and are committed to defending ALS research. Tell your member of Congress to protect lifesaving research! Take Action Now: https://t.co/JVTa9jyNwj

[Target ALS @TargetALS_fdn]

Yesterday, Target ALS founder Dan Doctoroff was celebrated with the naming of a street in his honor. From creating Hudson Yards to founding Target ALS, Dan has always led with vision, courage, and an unwavering belief in what’s possible.

[Siteman Cancer Center @SitemanCenter]

What a weekend — thank you, @PedalTheCause!

Our hearts are full thanks to the thousands of riders, spinners, donors, sponsors, volunteers and others who gave their all to support @WashUMedicine cancer research at Siteman Cancer Center and Siteman Kids @STLChildrens Hospital.

We can’t thank you enough! Together, we are building a world without cancer!

[nature @Nature]

Robert F. Kennedy Jr announced that the US federal government is terminating US$500 million worth of grants for mRNA vaccine research.

We must never, ever, forget that millions are alive today, or in better health, because of this life-saving technology.

https://t.co/Y6HIzyQ8Qj

[ALS Network @youralsnetwork]

ALS research and care are at risk.
Nationwide funding freezes and cuts threaten access to expert care and the breakthroughs people with ALS urgently need.

We call on public leaders to protect the funding that fuels hope — for ALS and other neurodegenerative diseases. Lives depend on it. Read the ALS Network’s full statement here: https://t.co/I531eZZsTT

[Science Magazine @ScienceMagazine]

Drawing the mind, one neuron at a time: A 2022 book walks readers through the life and work of Santiago Ramón y Cajal, the Spaniard whom many consider the founder of modern #neuroscience.

Check out the #ScienceBooks Review on #BookLoversDay: https://t.co/zECNwH3GPe

[Ayala Lab @AyalaLab1]

Odds of winning NIH grants plummet as new funding policy and spending delays bite | Science | AAAS https://t.co/TDggA2KHsI

[Cell @CellCellPress]

In the latest issue! Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates https://t.co/fb32T3F9zo

[Ayala Lab @AyalaLab1]

Call your representatives to stop slashing the budget of federal funded research in the BBB.
Their numbers can be found @5calls.org. #protect_research #science_saves_lives

[Target ALS @TargetALS_fdn]

This #LouGehrigDay, we honor a legend whose life was forever changed by ALS—and whose name gives us strength to drive #ALSResearch to end it.

Join us at the ballpark this week for #MLB games celebrating Lou's legacy and the ALS community.

Get tickets: https://t.co/hwyfrlnYNy

[Alzforum @alzforum]

Scientists uncover a combination of liquid-liquid phase separation and oxidation that may drive TDP-43 aggregation in ALS. @HymanLab @Alberti_Lab_TUD https://t.co/dWBiX4netx

[Saint Louis University @SLU_Official]

"We remember the joy that Pope Francis embodied and the humility with which he led."

Today, Saint Louis University joins the world in mourning the loss of Pope Francis, the first Jesuit to serve as pontiff. Read a message by President Fred P. Pestello, Ph.D., as he reflects on the legacy of Pope Francis and his impact on the world.

📷 by Mazur/catholicnews.org.uk

Read: https://t.co/FvDgTo1R6n

[Ayala Lab @AyalaLab1]

Women, minorities fired in purge of NIH science review boards https://t.co/xkm8Dpmqe9

[Ayala Lab @AyalaLab1]

SCIENCE WORKS #ProtectResearch #ScienceSavesLives #StandUpForScience2025
Clinical trials test the safety of stem-cell therapy for Parkinson’s disease https://t.co/EXwU2mzaPb

[Mahmoud Bukar Maina PhD FRSA @mahmoudbukar]

1/ 🌍 It’s finally out!

Introducing the #AfricaniPSCInitiative, an open-access Somatic & Stem Cell Bank featuring rigorously profiled #iPSC lines from indigenous Africans. Huge thanks to @karchlab, who helped make this possible. See: https://t.co/EikMHu2pHI

[Helen Branswell 🇨🇦 @HelenBranswell]

Secretary Kennedy seems to believe that vaccines against respiratory bugs that target a single antigen don't work.
People who have studied and designed vaccines beg to differ.
With multiple pending #Covid vaccines before #FDA, this may not bode well. https://t.co/sx1zKdC8VA

[Ayala Lab @AyalaLab1]

@gonzalo_lab @SLUbiochem Congratulations to the Gonzalo team!! Woohoo

[WashU Medicine Neurology @WashUNeurology]

There is phenomenal work being done on Alzheimer's and dementia at WashU Medicine Neurology and across #WashUMedicine, and we have gathered it all in one place for you.

Take a minute to read through some of these groundbreaking stories: https://t.co/ZXDsJRh29f

[Ayala Lab @AyalaLab1]

@SenBillCassidy & @SenSanders must set the record straight at the HELP hearing with RFK April 10: Stop decimating research and U.S. health! https://t.co/b6vf98Km8r

[Priya R. Banerjee @BanerjeeLab_UB]

Happy to share our new preprint on small molecule mediated inhibition of aging of biomolecular condensates.