BioSpace

Your source for biopharma news and jobs

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Troriluzole, in development for spinocerebellar ataxia, was rejected nearly a year ago when the FDA took issue with the design of Biohaven’s registrational study. The FDA agreed to review the application and issue a decision in the first quarter of 2027.

https://t.co/X05QnNe8Ts

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A year after announcing it would lay off up to 500 employees, Ferring Pharmaceuticals is again trimming its workforce. The Switzerland-based pharma has focused its U.S. resources on areas that better support its strategic priorities.

https://t.co/wyUtBJk2rv

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The sector’s IPO tally has surpassed each of the past four years, with four October debuts adding momentum—but activity still remains well below the COVID-19 boom that saw nearly 100 public debuts in 2021.

https://t.co/bXZowohT4e

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The approval of Hibsago has created a new market for a handful of biopharmas, including Gilead, Arrowhead, and Vir, to fill in.

https://t.co/XzEHwvNBXH

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Aside from RG6540, Roche also discontinued a host of other early-stage assets, including an antisense oligonucleotide for Alzheimer’s disease and a small-molecule candidate for geographic atrophy.

https://t.co/9eBm7ArzmQ

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Brepocitinib is on a roll. After its autoimmune skin disease approval, Roivant subsidiary Priovant’s drug hit all primary and secondary endpoints in two Phase 3 non-infectious uveitis trials, leading analysts to note the agent “looked superior to Humira.”

https://t.co/AkXBuhlAl0

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At the European Society for Medical Oncology meeting this weekend, Merck will showcase three late-stage trials of its Kelun-Biotech–partnered TROP2-directed antibody sac-TMT that VP of Chemistry Alan Northrup says gets the payload release “just right.”

https://t.co/Mfcxqcy2KE

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The $100,000 H-1B visa fee has significantly changed who biopharma companies hire, but it’s not the only policy move affecting foreign-born job seekers in the U.S. Dave Bowers (EPM Scientific) and Audrea Golding (Fragomen) discuss the latest developments.

https://t.co/PsxuXXfKyJ

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On Denatured, Bruce Culleton, CEO at ProKidney, and Demetri Maxim, CEO at Nephrogen, discuss why kidney disease challenges cell and gene therapies and how delivery strategies, new therapies and regulatory clarity could support commercially viable options.

https://t.co/KbVTS05C9n

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Funding an academic exit, leaving ecology and evolutionary biology for biomedical engineering, and moving from business development to entrepreneurship shaped 3 careers.

https://t.co/XRh9Qm9en0

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Pfizer is saying goodbye to an unspecified number of employees across its manufacturing operations, a spokesperson confirmed to BioSpace via email on Tuesday.

https://t.co/Hxss1JAyFq

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Looking for a remote biopharma position? Check out the BioSpace list of eight companies hiring life sciences professionals like you.

https://t.co/O2XxaMGVTu

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Just one-third of patients prescribed new medicines filled them within 30 days, with a new report from the Institute for Clinical and Economic Review and West Health suggesting that cost is the problem.

https://t.co/F4SUPjUUfm

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Hibsago’s approval—a functional cure for certain patients with a hepatitis B infection—further validates Ionis Pharmaceuticals’ antisense platform, which has already generated two other new drug approvals this year.

https://t.co/grXUKC3FZK

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Post hoc analyses in women divided by menopausal status show how Novo’s next-generation GLP-1 drug affects key cohorts of patients.

https://t.co/VH6jTc2iyr

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A strong crossover raise can suggest that a company has “reached a level of maturity” and could go public soon, according to Sofinnova Investments’ Jim Healy.

https://t.co/u0yLxbGYnt

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China may be taking the majority of licensing deals this year but those transactions don’t tell the whole story, according to Locust Walk, which points to the spike in M&A among U.S. biotechs as leveling the playing field.

https://t.co/VvG01kpz1Y

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Compensation can feel like a verdict on your value. Executive coach Angela Justice explains why companies are usually pricing the job, not the person doing it—and how understanding the difference can help you make better career decisions.

https://t.co/Zc9iCDnsqY

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Rapport Therapeutics clocked its second Phase 2 win in 14 months for RAP-219—which the company is positioning as a potential pipeline-in-a-product—this time showing improvement in symptoms of bipolar mania.

https://t.co/axm0POrarG

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Enlivex is cutting about 60% of staff to reduce costs and focus on mid-stage development of its knee osteoarthritis cell therapy, Allocetra. After another disappointing duravyu readout in wet AMD, EyePoint is reprioritizing and cutting about 53% of staff.

https://t.co/yMhMnShZ6L