“As more data comes in… more cardiac experts are coming to believe the COVID-19 virus can infect the heart muscle. An initial study found cardiac damage in as many as 1 in 5 patients, leading to heart failure and death even among those who show no signs of respiratory distress.”
#Cilia cells clear mucus out of #lungs.
#Coronavirus infects cilia by binding to #ACE2 enzymes prevalent in lungs, possibly explaining the excess mucus appearing in #respiratory diseases.
“…reported to enter cells via binding to ACE2, followed by its priming by TMPRSS2.”
Inflammation Triggered By Allergies 🤧:
“#Allergies… are an #inflammatory disease characterised by disequilibrium of T-lymphocytes and tissue eosinophilia.”
“Elevated levels of #proinflammatory#cytokines seen… more pronounced in [seasonal allergies].”
https://t.co/HAdRYGcqBv
BPC-157 peptide slows growth of human #melanoma (skin cancer) #tumor cell line in #vitro:
“…by inactivating the TLR4/NF-κB signaling pathway.”
https://t.co/soAnOAicBA
1st coronavirus has a nearly identical ACE2 binding mechanism as the modern pandemic corona.
Drugs blocking #endosomes from releasing the original SARS-CoV to #ACE2 enzymes, & the protease activation that follows, may be worth investigating for #COVID19.
https://t.co/yPleBPqp8X
High doses of #chloroquine ended a #COVID19 trial due to causing #QT prolongation in patients (heart muscle recharges between beats slower than usual e.g. #arrhythmia).
“A “high dose” of (600 milligrams twice daily for 10 days)…”
https://t.co/aoltjO5WU9
“MOTS-c, a peptide encoded by the mitochondrial DNA, can localize to the nucleus. Metabolic stress triggers AMPK-dependent translocation of MOTS-c to the nucleus.
MOTS-c can regulate nuclear gene expression and promote cellular stress resistance against metabolic stress.”
Senescent cells contain damaged DNA instructions that prevent them from being able to eliminate themselves. This disruption of cellular function quickens death.
FOXO4-DRI removes many senescence cells by selectively targeting their distinctive structures.
https://t.co/n1aYwtsnaL
My Fall 2018 #KindnessDiaries Speaking Tour kicks off in late Sept through mid-Nov 😀 I will be visiting 6 places in US/CAN including Salt Lake City, Las Vegas, Grand Rapids, Philadelphia, Prince George B.C., Dartmouth Nova Scotia. If you want me to come speak, message me!
25% off all print products, enter code sum 25 at checkout. Through 8/31/18 at 11:59 PM EST. Business cards, post cards. Discount does not apply to shipping and tax, EDDM postcards,postage, and promotional products. https://t.co/DVN7uRBBMG
Small purchases = big results! Now users across Europe can set a recurring order for bitcoin and build up their balance over time 🐢 https://t.co/Re8hicA9vy
Do you want a shot at designing the logo of CoinMarketCap? We want to see what you’ve got!
We are excited to announce the launch of our 99designs campaign to find our NEW logo!
The first round of submissions is NOW live and will be concluded 12/12.
https://t.co/OEZqM61M8I