Julia Heiby

Postdoc at the Leibniz Institute on Aging and Stanford, working on functional proteomics. #lysosomes #massspectrometry

[Julia Heiby @blue_ceil]

(1/3) Happy to share my first review together with @AOri_Lab on organelle dysfunction in aging and age-related diseases!
Are you curious about the impact aging has on mitochondria and lysosomes?
Then read this👉https://t.co/fMkDFhIilm

[Julia Heiby @blue_ceil]

@LeibnizFLI @Stanford_ChEMH @UniJena @ali_ghoochani @AOri_lab @abu_remaileh Many thanks to our colleagues and collaborators in Jena for their key contributions, including @nizzle_fe_shizz, @DomenicoFraia and the Kaether Lab.
A true multi-institutional effort.

[Julia Heiby @blue_ceil]

Our Brain LysoAtlas is now out in Cell!
We map the cell-type-specific protein composition of lysosomes and link SLC45A1 to neurological disease.
Joint work by @LeibnizFLI, @Stanford_ChEMH & collaborators incl. @UniJena, led by @ali_ghoochani, @AOri_lab & @abu_remaileh.

[Julia Heiby @blue_ceil]

@LeibnizFLI @Stanford_ChEMH @UniJena @ali_ghoochani @AOri_lab @abu_remaileh 📄 Read the article: https://t.co/Nq47UT9oz9
🌐 Explore the data via our interactive, browser-based Lysosomal Brain Protein Atlas:
https://t.co/tCVmEatmjV

[Julia Heiby @blue_ceil]

@InaquiConQ @Luis_BonetPonce Thank you Iñaqui!

[Julia Heiby @blue_ceil]

🚨New Paper Alert🚨Explore our latest work on the Lysosomal BrainAtlas, now available on bioRxiv! This comprehensive resource maps lysosomal proteins in specific brain cell types and identifies SLC45A1 as a novel neuron-specific lysosomal sugar transporter https://t.co/NW5i3KMxXW

[Julia Heiby @blue_ceil]

@Ella_Maru Thanks Ella!

[Julia Heiby @blue_ceil]

@unnaturalGerti Thank you Gerti!

[Julia Heiby @blue_ceil]

#CellBiology #Neuroscience #Lysosomes #BrainAtlas #Neurodegeneration #SLC45A1

[Julia Heiby @blue_ceil]

@ali_ghoochani Here, we uncover the key roles of transporter SLC45A1 as a novel regulator of both lysosomal acidity and sugar export revealing previously unknown mechanisms of cell-type specific lysosomal functions, relevant to neurological diseases

[Julia Heiby @blue_ceil]

In this study co-led with @ali_ghoochani, we used LysoIP & high-res mass spectrometry to create the first lysosomal protein atlas across neurons, astrocytes, microglia & oligodendrocytes. A breakthrough for understanding cell-type-specific lysosomal functions in the brain!

[Julia Heiby @blue_ceil]

@UcheMedoh Congrats, Uche! Very happy for you!

[Leibniz-Institut für Alternsforschung (FLI) @LeibnizFLI]

Congratulations on the outstanding publication regarding a potential therapeutic approach for Batten disease, a devastating childhood neurodegenerative disorder. Find out more👉https://t.co/Ro0szy4NOd

@AOri_lab @abu_remaileh @blue_ceil @Stanford

[Julia Heiby @blue_ceil]

@NikitaRaj_ Congrats, Nikita! Well deserved!

[Julia Heiby @blue_ceil]

@Bhar_Meenakshi @DrDoolittlePhD @dan_sillence Congrats!

[Julia Heiby @blue_ceil]

@NikitaRaj_ @AdvSciNews Congrats! 🙂

[Julia Heiby @blue_ceil]

@unnaturalGerti @LeibnizFLI @AOri_lab @nclStiftung Thanks Gerti ☺️

[Leibniz-Institut für Alternsforschung (FLI) @LeibnizFLI]

Herzlichen Glückwunsch💐Alessandro Ori @AOri_lab + Julia Heiby @blue_ceil haben für ihr Projekt “Targeting alterations of the lysosomal proteome in Batten disease” den Forschungspreis der @nclStiftung erhalten. Weitere Infos👉https://t.co/O9ZUIBWBov
#battendisease #Kinderdemenz

[Julia Heiby @blue_ceil]

@abu_remaileh @Stanford_ChEMH @DAAD_Germany @LeibnizFLI Thank you, Monther!

[Julia Heiby @blue_ceil]

Thanks to the @abu_remaileh lab and @Stanford_ChEMH for having me these past months and to the @DAAD_Germany and @LeibnizFLI for making this possible. It has been an outstanding experience! Bitter sweet to go back, I will miss the people and this place for sure.

[Julia Heiby @blue_ceil]

What a day to be at @Stanford celebrating with @CarolynBertozzi for winning the Nobel prize, together with her lab, the @Abu_Remaileh lab and Stanford ChEMH. Congrats!