Centivax

Smash the mutants

[Centivax @centivax]

https://t.co/TxN42Hm5rK

[Centivax @centivax]

https://t.co/xBz4l3IUHp

[Elliot Hershberg @ElliotHershberg]

What if flu vaccines really worked?

And I mean *really* worked—to the point that humanity's endemic relationship with influenza became history, not an ongoing global health challenge.

What if we could mitigate *all* rapidly mutating pathogens?

This is why Jake Glanville founded Centivax. His life mission is to "finish what Edward Jenner started" by developing universal vaccines that accelerate humanity's transition to a post-pathogen future.

Jake is exactly the type of Technical Founder we look to partner with at Amplify. He was an early pioneer of computational antibody design at Pfizer, before becoming one of the first graduate students in Computional & Systems Biology at Stanford with Mark Davis.

He's synthesized a lifetime of work into a distinct—and somewhat contrarian—idea for developing universal vaccines.

And the team he's assembled is equally extraordinary. For example, Centivax's CMO, Jerry Sadoff, is one of the most prolific vaccine developers alive.

It's truly a privilege for us to participate in the Series A syndicate for Centivax. Over the last decade, Jake and the team have assembled a comprehensive pre-clinical data package for their lead flu program.

The only remaining experiment is to see if this translates to humans, which is what this round underwrites.

If this technology is successful, the impact will be enormous. And the story of this team's perseverance will require it's own book in the biotech canon.

[Steve Jurvetson @FutureJurvetson]

Smash the mutants 🦠 to end the pandemic era for humanity
— with a single shot for all flu and then coronaviruses, HIV, herpes, malaria, cancer and more! These scourges have evaded effective vaccines because they continuously mutate their outer epitopes to evade our immune system. Centivax is the first to show a universal vaccine working in multiple animals and human organoids. With this Series A funding, led by Future Ventures, they will take it to humans.

“Universal vaccines won’t just be safer, more reliable and more convenient medicine - their commercialization will end the pandemic era” — Jacob Glanville, PhD, co-founder and CEO of Centivax (in 2nd photo I took at SynBioBeta)

“I have been on a quest to find a credible antiviral breakthrough for over 20 years. I first became enamored with the prospect of a universal vaccine via our philanthropy. Centivax has already demonstrated their universal immunity platform in antivenom. Their unique approach will hopefully lead to a historic transition to a post-pandemic era for humanity” — me

The growing portfolio underscores the technology’s broad potential against rapidly mutating threats, including viruses, bacteria, protozoan, fungal and parasitic pathogens, but also extending to broad healthspan indications spanning oncology, autoimmunity, cardiovascular disease and neurodegeneration.

We also welcome to the board Dr. Emilio Emini, former SVP of Vaccine R&D at Pfizer and Merck and CEO of the Gates Medical Research Institute where he ran their HIV and TB programs.

“Centivax designed a vaccine that contains a whopping 22 different mRNA molecules encoding proteins from flu strains spanning the past century. The South San Francisco-based company claims animal studies show that the immune system can spot the commonalities between the strains and focus its attack on the tidbits of the virus that are unlikely to change from season to season. ‘They always have this Achilles’ heel, a little spot that they can’t mutate. Otherwise, they’re no longer infectious,’ Centivax founder and CEO Jacob Glanville told Endpoints. ‘A universal vaccine, once it’s approved, is just going to be called ‘the vaccine’ because why would people take anything else?

‘FDA Commissioner Marty Makary has predicted that a universal flu vaccine could be available within five years, a timeline that aligns with Centivax’s plans. ‘Every year we have a global outbreak, which is nuts,’ Glanville said. ‘If we do our jobs well, then the pandemic era is over.’”
— Today’s news (free with registration): https://t.co/eJb3KaEaK9

Company site: https://t.co/8DVZ9irDpq

[Centivax @centivax]

Our director of herpetology, Tim Friede, was on Late Night with Seth Meyers in a segment called “The Kind of Story We Need Right Now.” #Centivax #TeamCentivax #CentivaxInnovation #CentivaxScience #PublicHealth #InfectiousDiseases #GlobalHealth #HealthInnovation

[Centivax @centivax]

It is Centivax's mission to accelerate the world’s transition to a post-pathogen humanity.

#Centivax #TeamCentivax #CentivaxInnovation #CentivaxScience
#PublicHealth #InfectiousDiseases #GlobalHealth #HealthInnovation #PandemicPreparedness #ImmunizationMatters #FluShot

[Centivax @centivax]

Tim Friede and Centivax on the cover of the New York Times.

[Centivax @centivax]

https://t.co/4lUmxBKUHZ

[Centivax @centivax]

Dr. Glanville and Tim Friede live on CNN.

[Centivax @centivax]

https://t.co/kpmCrbr87U

[Centivax @centivax]

The global vaccine research funder will award up to US $5 million to progress a pioneering pan-influenza clinical candidate developed by US-based start-up Centivax into human trials.
https://t.co/boOoAUggef

[Centivax @centivax]

"Having a trusted partner to conduct rigorous in vitro development of our batch release potency assay is crucial for the immediate need of initiating clinical trials of our first universal vaccine candidate." -Jacob Glanville, CEO. https://t.co/iS8HNzzqGC

[Charlie Petty @incredutility]

Jake Glanville from @centivax talking about the importance of next gen influenza vaccines

[Centivax @centivax]

Dr. Glanville discusses "Why we need a broad spectrum influenza vaccine" with Radio New Zealand.
#influenza #InfluenzaAwareness #Centivax #vaccine #immunology #publichealth #biotech #researchanddevelopment #scientist #QuadDemic
https://t.co/PgmRFgRH9P

[Centivax @centivax]

We are honored to join the @flucoalition as one of its newest members. Read more here: https://t.co/IXt3XYuPFZ

[Coalition to Stop Flu @flucoalition]

The Coalition is excited to welcome @Blueprintbio and @centivax as its newest members. Blueprint Biosecurity is a nonprofit dedicated to reducing the threat of airborne disease, and Centivax is a leader in universal vaccine development. Read more here: https://t.co/BfBg6UCB17

[Centivax @centivax]

The Science of Innovation: Jake Glanville on Revolutionizing Biotech and Pandemic Prevention. In this episode ofSync’d Up, host Andreas Dankelmann sits down with Jake Glanville, founder and CEO of Centivax, to discuss his groundbreaking work in biotech. https://t.co/WlxSXGs4Yj

[Centivax @centivax]

A deadly strain of bird flu has been detected in dairy cows for the first time. Dr. Jacob Glanville, CEO of biotech firm Centivax, joins "The Daily Report" to explain why this discovery is concerning and how big a risk it poses to public health.
https://t.co/J3GfU7VvvU

[Centivax @centivax]

https://t.co/7MlZDQJVMb

[Centivax @centivax]

We are thrilled to be announced as one of the awardees for the #BLUEKNIGHT #QuickFireChallenge. Looking ahead with great anticipation to continue innovating for a better and safer future.