𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛

Professor of Primary Care Diabetes & Vascular Medicine, University of Leicester

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

In a gin bar in Tokyo

Have a great evening friends 🥂

@mmamas1973
@TBattelino

[NIHR ARC East Midlands @ARC_EM]

Working on an Equality Impact Assessment? 🙋

Our free workshop is coming up Wed 20 May, 1–3pm via Zoom. Open to everyone. Small groups, practical guidance, real answers. Hosted with @ethnichealthres.

Book now 👇 #EqualityImpact #InclusiveResearch
https://t.co/QVY8jotjEO

[Leicester Real World Evidence (LRWE) @LRWEUnit]

Welcome to our new Associate Professor, Carlos Wong! 🎉

An expert in pharmacoepidemiology and health services research, his work spans health economics, EHR data, RSV vaccine effectiveness, and AI in healthcare.

Great to have you with us, Carlos

[Centre for Ethnic Health Research @EthnicHealthRes]

10 years of the Centre! A decade of listening, learning, and driving change.

Hearing Kamlesh reflect on this milestone reminds us what the day truly stood for. It was about recognising the journey to reduce health inequalities❤️

[NIHR ARC East Midlands @ARC_EM]

🎉 Congratulations to the Centre for Ethnic Health Research on 10 years of important work to reduce health inequalities.

@ARC_EM is proud to have supported the Centre’s development, and to see our Co-Director, Professor @kamleshkhunti, reflect on this significant milestone.

[Research at Leicester's Hospitals @LeicResearch]

A study carried out by researchers with funding from the #NIHRBRCLeicester has highlighted several important areas of unmet need among adults with #type2diabetes and diabetic foot ulcers.

Inlcuding:
⭕️improved, personalised and sustained access to education
⭕️behaviour change support through shared decision making, with input from psychological support services
⭕️tailored physical activity interventions and specialist services.

@LDC_tweets
Read the full paper below:

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Across a broad CRM population

SGLT2i reduce cardiovascular death or heart failure hospitalisation and all-cause death irrespective of BMI.

https://t.co/ZJtoaVehvl

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Diabetic foot ulcer disease has a major impact on people with diabetes

Our qualitative study led by Molly and @MichelleHadji

Funded by @NIHRresearch

https://t.co/hP61X80GRr

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

SGLT2 inhibitors - meta-analysis 18 RCTs

🫀 Reduce CV mortality
🩺 Improve kidney outcomes
📉 Lower overall mortality risk

Benefits seen in diabetes, heart failure & CKD — with signals of added survival benefit across age groups.

A true cornerstone of cardiorenal protection.

https://t.co/S4O3LYgJEf

sglt218

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@gandaom You are always welcome Ombhai🙏🏻

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Indian Kesar Mango Mojito

Have a great bank holiday weekend 🥂

@mmamas1973

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@ppvernon Congratulations Patrick. Very well deserved 👏👏👏

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@Rabi1430 Seasonal fruits

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@AnastasiaSMihai 👌🥂

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@hvanspall @mmamas1973 Sounds lovely. Enjoy 🥂

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@INDIACCDC @drmohanv @aiims_newdelhi @DrDPrabhakaran @DrPoornimaP @drapjtweets @ShifalikaGoenka @ishita_r Congratulations Nikhil. Very well deserved 👏👏👏

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Review: Metabolic liver disease: A summary of major guidelines and identifying opportunities to improve future guidelines

https://t.co/iOkWK2QdDO

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Exercise isn’t “off limits” in people with T2 diabetes and foot ulcers

In our current @NIHRARCs MiFoot RCT, people with diabetic foot ulcers told us they were getting confused regarding exercise

They were getting mixed messages from HCPs

So we developed these practical recommendations

Led by @vicki_johnson_w

• Screen risk first
• Individualise prescriptions
• Prioritise non-weight bearing exercise
• Emphasise foot care + self-monitoring

Safe movement = better cardiometabolic outcomes.

https://t.co/tZ4ikpSpJQ

@uniofleicester @NIHRARCs @ARC_EM @GoggleDocs

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Meta-analysis of SGLT2 inhibitors

18 RCTs including 95,913 patients

🫀 Reduce CV mortality
🩺 Improve kidney outcomes
📉 Lower overall mortality risk

Benefits seen in diabetes, heart failure & CKD — with signals of added survival benefit across age groups.

A true cornerstone of cardiorenal protection.

https://t.co/S4O3LYgJEf

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

@AmarPut No chance 🤦🏽

[𝐂𝐨𝐫𝐫𝐢𝐧𝐚 𝚂𝚒𝚗𝚌𝚕𝚊𝚒𝚛 @CorrinaSinclair]

Sleep and metabolism are tightly linked.

🛌 ~7.3 hrs = optimal insulin sensitivity -oh dear 😔

📈 Too little sleep → worse insulin resistance
📉 Too much sleep → also harmful

🔄 Weekend catch-up helps only if sleep-deprived (1–2 hrs), but >2 hrs may backfire

Personalised sleep matters for metabolic health.

https://t.co/9lALzR03HJ