@kennyfgan With a team of kids in the naighboorhood with varying skillsโฆ coached by someoneโs dad that is rough around the edges with all of them figuring it out
Excited to share our new ACS Chemical Biology paper.
We show that a small molecule RiboTAC selectively degrades pre-miR-21 and rescues disease-relevant pathways in cellular models of fibrosis.
Another step toward drugging disease-driving RNAs with small molecules.
https://t.co/d0HgRFtcX6
A chemoinformatics-guided platform for efficient discovery of RNA-binding small molecules: Proof-of-concept for myotonic dystrophy type 1 | bioRxiv https://t.co/cvUBam6LX0