Elliot Dine

Post-doc in @LabYoule. Playing with protein phase separation, optogenetics and selective autophagy. Tweets represent my own view and not that of the @NIH

[Elliot Dine @ElliotDine]

@DKThomp Loved the article, but one thing not mentioned was Baumol, which I think is quite relevant. Much more expensive to get outside help for child-care leads to more intensive parenting overall.

[Lifei jiang @jiang_lifei]

What happens when an assembly line runs too fast?

Things break down, like the chocolate factory scene from “I Love Lucy” 🍫

Cells have assembly lines too, like ribosome biogenesis

We show that cancer cells push this system to the breaking point (1/10)

https://t.co/CI6j9sC7O6

[Jason Buenrostro @JD_Buenrostro]

It’s well known that inflammation increases cancer risk, but how?

The answer: the epigenome "remembers" inflammation and primes stem cells for cancer.

Here is our paper: https://t.co/FcnkLdpiKZ
And a special shoutout to the lead author @snaga13

A 🧵

[Natalie Niemi @nieminm]

What a fun surprise to find that our work has been featured in a @JCellBiol spotlight!! Many thanks to Carlotta Peselj and Nora Vögtle for the great write up!

[Jason Sheltzer @JSheltzer]

New from my lab on bioRxiv - we found an existing drug that appears to be safe in humans that selectively kills chemotherapy-resistant cancer cells.

[Elliot Dine @ElliotDine]

@SeanFennessey @TheBigPic The Mets are the definition of a sports horror movie...(and this Reds fans is very happy about that!)

[Elliot Dine @ElliotDine]

Super cool work from a super cool scientist!

[siddhartha jena @epijenatics]

Excited to share my postdoc work, out on bioRxiv today! Histones package DNA into nucleosomes to form the building blocks of chromatin, but how modular and programmable is this system? 1/9

[siddhartha jena @epijenatics]

Excited to share my postdoc work, out on bioRxiv today! Histones package DNA into nucleosomes to form the building blocks of chromatin, but how modular and programmable is this system? 1/9

[Elliot Dine @ElliotDine]

@NateSilver538 As someone who grew up in DC area and now lives here permanently, Washington cannot be that high - way too many transplants and many locals gave up fandom in the Snyder era. That ranking is way too biased based on what Jayden Daniels did last year.

[brangwynnelab @brangwynnelab]

Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of @sofiquinodoz & @jiang_lifei w/ @LafontaineLab & Sebastian Klinge and other fantastic co-authors https://t.co/68W7vEHmps

[Elliot Dine @ElliotDine]

@JerusalemDemsas @ezraklein @DKThomp On housing abundance. While NIMBYism is not the way to encourage growth in less populated places, is it really a worthwhile goal to encourage more super-city growth. Wouldn't it lead that to more resentment/polarization? Think of what happens in sports with "small markets".

[Elliot Dine @ElliotDine]

@PodSaveAmerica Given Harris's over performance in the swing states compared to the overall country, why is there a focus on trans issues, since it seems from those swing state results that Trumps attack ads were not effective relative to Kamala's?

[Elliot Dine @ElliotDine]

@BugajLab @NatureComms @David_GonzMar @LeeeRoth Congrats Lukasz, nice to see this fully published.

[Harry McNamara @h4rrymcnamara]

Our study decoding gastruloid symmetry breaking is now live @NatureCellBio!

https://t.co/rRWRy853Yq

Thank you to the NCB edititorial team and to our reviewers for a constructive review process which helped improve our study. A thread on updates (1/n):

[Elliot Dine @ElliotDine]

A little late to this but this is a real fun read for condensate enthusiasts: https://t.co/Grz6fqJKK8

[Vamsi Mootha @VamsiMootha]

Today's @NobelPrize for John Hopfield recognizes only one of his contributions - he's a true polymath. I strongly recommend his solo author PNAS papers (i) long-range e- tunneling in proteins (1974), (ii) kinetic proof-reading (1974), (iii) Hopfield nets (1982). Each is a gem!

[Randy Clarke @wmataGM]

Today @wmata announced a $28m FY24 year end surplus. This was due to aggressive cost mgmt reducing expenses by $62m. That is on top of $50+m savings developing the FY24 budget. So #wmata is delivering more and better service for $100+m less. Excellent job by the team!🧵1/3

[Xin Zhou Lab @xinzhoulab]

We are excited to share our lab’s first research article! https://t.co/GKlHK0WjLz We have developed Transferrin Receptor Targeting Chimeras (TransTACs), a novel class of heterobispecific antibodies designed for targeted degradation of membrane proteins. https://t.co/spmBr6jp7w

[Elliot Dine @ElliotDine]

@bsabari @MolecularCell @Nancybrillet @UTSWGradSchool Congrats! Awesome cover and article

[Elliot Dine @ElliotDine]

@TheBigPic For Sean, favorite place to hike in Ithaca/Finger Lakes?