Epilepsia Open

Epilepsia Open is the open access journal of the International League Against Epilepsy (ILAE).

[Epilepsia Open @EpilepsiaOpen]

These systems hold the potential to overcome obstacles like the BBB and improve therapeutic efficacy.
https://t.co/dijA4KWRiY

#epilepsy #ILAE #epilepsiaopen #BBB #nanodeliverysystem #neurological

[Epilepsia Open @EpilepsiaOpen]

VNS responders and VNS nonresponders can be differentiated based on resting-state invasive EEG analysis.
https://t.co/fD5X4oEgID

#epilepsy #ILAE #epilepsiaopen #highfrequencyoscillations #interictalepileptiformdischarges #intracerebralrecording #invasiveEEG #relativeentropy

[Epilepsia Open @EpilepsiaOpen]

Although difficult to detect and treat, the majority of patients with FCD1 experience meaningful postoperative improvement in seizure control.
https://t.co/7LOj82YDyx

#epilepsy #ILAE #epilepsiaopen #drugresistant #epilepsysurgery #FCD #pediatricneurosurgery

[Epilepsia Open @EpilepsiaOpen]

Cenobamate showed meaningful effectiveness and high retention in a large real-world cohort of drug-resistant epilepsy.
https://t.co/6LAVxWCJIS

#epilepsy #ILAE #epilepsiaopen #Cenobamate #DrugResistantEpilepsy #RealWorldEvidence

[Epilepsia Open @EpilepsiaOpen]

ES-481 is a potent and selective antagonist of the TARP-y8-dependent AMPA receptor, highly expressed in the hippocampus and limbic system.
https://t.co/hWaUdi4SS0

#epilepsy #ILAE #epilepsiaopen #antiseizuremedication #clinicaltrial #Phase2a #seizures

[Epilepsia Open @EpilepsiaOpen]

Pulse-level PPG quality assessment before HR estimation enhances wearable seizure detection in children with epilepsy.
https://t.co/2nKQVaofh6

#seizure #SDD #paediatricepilepsy #wearable #epilepsy #ilae #epilepsiaopen

[Epilepsia Open @EpilepsiaOpen]

This large international study evaluated clinicians' accuracy and comfort level in using smartphone videos to identify ES.
https://t.co/Tf0geSmgnj

#epilepsy #ILAE #epilepsiaopen #diagnosis #epilepticspasms #infantileepilepticspasmssyndrome #smartphonevideo #triage

[Epilepsia Open @EpilepsiaOpen]

Depressive symptoms and suicidal ideation are highly prevalent among adults with epilepsy in Georgia, highlighting critical unmet mental health needs
https://t.co/yoxGIQJzuY

#epilepsy #ILAE #epilepsiaopen #Antiseizuremedication #screeningtests #suicidalideation

[Epilepsia Open @EpilepsiaOpen]

Short cenobamate interruptions (~1 week) may not require re-titration. No hypersensitivity observed on restart in a cohort of 32 patients
https://t.co/bSnMBv3BmX

#epilepsy #ILAE #epilepsiaopen #adverseeffects #drugsafety #epilepsymonitoringunit #medication #adherence #rash

[Epilepsia Open @EpilepsiaOpen]

We are pleased to share that Epilepsia Open's Impact Factor has increased 3.4.

Thank you to our authors, reviewers, Associate Editors, Editorial Board members, and readers for your continued support and contributions to the journal.

#Epilepsy #ILAE #EpilepsiaOpen

[Epilepsia Open @EpilepsiaOpen]

Between treatments, early evidence suggests fenfluramine and cannabidiol may improve alertness, behavior, sleep, and communication beyond seizures.
https://t.co/F2Z8mOCCiD

#epilepsy #ILAE #epilepsiaopen #biopsychosocialsystem #caregiverburden #DEE #patientcenteredoutcomes #QOL

[Epilepsia Open @EpilepsiaOpen]

Perampanel significantly reduced seizure frequency in patients with brain tumor-related epilepsy associated with high-grade gliomas.
https://t.co/zimQodnToE

#epilepsy #ILAE #epilepsiaopen #astrocytoma #glioblastoma #Perampanel #seizures

[Epilepsia Open @EpilepsiaOpen]

Resting-state functional connectivity in TLE was studied in 829 participants.
https://t.co/ZpVn923vJ8

#epilepsy #ILAE #epilepsiaopen #functionalMRI #restingstate #functionalconnectivity #temporallobeepilepsy

[Epilepsia Open @EpilepsiaOpen]

Cannabidiol, ethosuximide, and the selective Cav3 inhibitor, ulixacaltamide, reduced atypical absence seizures.
https://t.co/HCWA636bok

#epilepsy #ILAE #epilepsiaopen #animalmodels #antiseizuredrugs #cannabinoids #epilepticencephalopathy #GABRB3 #Ttypecalciumchannels

[Epilepsia Open @EpilepsiaOpen]

Congratulations to the 2026 Epilepsia Open Prize recipients!

Clinical Research: Ruotong Chen
Basic Science Research: Zining Liu

Recognizing outstanding epilepsy research published in 2025.

#Epilepsy #EpilepsyResearch #ILAE #EpilepsiaOpen

[Epilepsia Open @EpilepsiaOpen]

New in Epilepsia Open – June 7, 2026
https://t.co/yos2UW7VYx

Subscribe - https://t.co/yNKAXH7jk8

#epilepsy #epilepsiaopen #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch

[Epilepsia Open @EpilepsiaOpen]

This is a pilot of an upcoming larger educational project under the auspices of ILAE Neurobiology Commission.
https://t.co/TMh0IYCB5d

#epilepsy #ILAE #epilepsiaopen #basicscience #education #epilepsytraining #neurobiology

[Epilepsia Open @EpilepsiaOpen]

Collecting real-world data to contribute to the overall real-world evidence on phenotypes and genotypes of monogenic genetic epilepsies.
https://t.co/MAKOhttz5C

#epilepsy #ILAE #epilepsiaopen #3Dproteinstructure #predictiontool #chromosomalmicroarray #exomesequencing

[Epilepsia Open @EpilepsiaOpen]

The Editors of Epilepsia Open are pleased to announce the recipients of the 2026 Epilepsia Open Prize, recognizing outstanding clinical and basic science research published in 2025. Congratulations to this year's awardees!

https://t.co/um7cUpBKoA

#Epilepsy #epilepsiaopen

[Epilepsia Open @EpilepsiaOpen]

Moving from a typical Australian diet to a modified ketogenic diet increased food costs by 13% for females and 44% for males.
https://t.co/Ykgr8eKAkk

#epilepsy #ILAE #Epilepsiaopen #costanalysis #dietarytherapy #ketogenicdiet