FloMontel

Cuisinier et chimiste

[FloMontel @FloMontel]

@KLM_UK I never complain on social media but here too much is too much. Flight from Edinburgh to Amsterdam cancelled, ok it could happen but I got zero message from KLM and no one from KLM available there. @KLM is completely disorganised and this airport is not better and dirty

[FloMontel @FloMontel]

@mesuturkiye @Boehringer @BoehringerDE @boehringerus Thank you Mesut for your words, happy to share these great tool compounds with the scientific community :-)

[A. Mesut Erzurumluoğlu @mesuturkiye]

Happy to learn that @Boehringer is one of the few, if not the only Pharma company, to offer free molecules (e.g. HSD17B13 inhibitor, GPR142 agonist) to advance scientific knowledge.
Details and full list of (free!) molecules here:
https://t.co/QXTmu9eMy5
#drugdiscovery

[FloMontel @FloMontel]

Dear #Researchers, join us for our upcoming online seminar on how #openscience via #opnMe revealed epigenetic regulation of a pediatric cancer with poor prognosis through targeted protein degradation of chromatin remodeler subunits SMARC2/4. Register toda…https://t.co/jnvHqQLcQQ

[FloMontel @FloMontel]

Dear #Researchers, access a panel of74 well-characterized molecules for free and analyze more than 50 cellular signaling pathways with the chance to generate new insights into human or animal disease mechanisms. More on #opnMe
https://t.co/yq9DNSENil https://t.co/JTuomyohSc

[FloMontel @FloMontel]

Hi all, unfortunately we had a tech issue this afternoon/evening and we will have to postpone the ADDC webinar. Please keep in touch it will be even more exciting next time :-) #welovetechnology Thank you all for your understanding! https://t.co/GzjtzCSpVD

[FloMontel @FloMontel]

Dear #Researchers, at our next #opnMe online seminar, learn how rational design strategy led to the creation of ACBI1, a SMARCA2/4 degrader. Find out how ACBI1 was used by independent groups to reveal an oncogenic addiction in alveolar rhabdomyosarcoma, a…https://t.co/lQe5ilyK7d

[FloMontel @FloMontel]

Dear Network, please read this case study about the Chemogenomics Library that EUbOPEN is building with the support of Academic groups, EFPIA - European Federation of Pharmaceutical Industries and Associations partners and IMI/Innovative Health Initiative…https://t.co/IsDEa6SC8v

[FloMontel @FloMontel]

Dear #Researchers, join our next #opnMe online seminar on November 29 to find out how the #PROTAC degrader ACBI1 from opnMe helped to unveil a crucial role of SMARCA2/4 in alveolar rhabdomyosarcoma. Register today
https://t.co/k4SuINz9sx https://t.co/iNH0uxxVsu

[FloMontel @FloMontel]

Dear molecular Biologists screening for new pathways to tackle diseases, have you seen that you can get the entire collection of https://t.co/10krBSS7vL tool compounds on plates ready to use?
Visit us to learn more, thank you to t…https://t.co/3kRzLsdqrs https://t.co/Fd64qletE9

[FloMontel @FloMontel]

Dear Biologists, do you know that you that you can find the full sequence of >10 antibodies and tissues assays on the EUbOPEN website . Happy that Boehringer Ingelheim and https://t.co/10krBSS7vL participate to this great initiativ…https://t.co/1scQsplPb9 https://t.co/bVrWGV6cZ3

[FloMontel @FloMontel]

Dear Network, join this nice panel discussion the 10th of November organize by ADDC! Happy to have the opportunity to present Boehringer Ingelheim and #opnMe to the ADDC network. https://t.co/cW9q4ivgV6

[FloMontel @FloMontel]

Dear researchers, do you know that you can find on EUbOPEN a list of >50 high quality tool compounds for a large range of targets available for ordering on The Structural Genomics Consortium (SGC) portal. Boehringer Ingelheim and o…https://t.co/b2EEvLMG4I https://t.co/9MOUsF0dYO

[FloMontel @FloMontel]

Dear #Researchers, the liver shows remarkable regenerative capabilities after acute injury or resection. How would you propose to harness the underlying molecular mechanisms of its regenerative power as a novel intervention approach against late-stage NAS…https://t.co/QJAlUSIFrV

[FloMontel @FloMontel]

Dear #Researchers, ACBI2 is a highly potent PROTAC (proteolysis-targeting chimera) and shows strong selectivity for the BAF (SWI/SNF) complex ATPase SMARCA2 that has a critical role in chromatin remodeling. Access now for free on #opnMe…https://t.co/4Azs7FrVhz

[FloMontel @FloMontel]

Dear #Researchers, generate new insights into cellular processes underlying human or animal diseases by analyzing more than 50 signaling pathways with our comprehensive molecule library from #opnMe. Learn more
https://t.co/BI2BSLCOhc https://t.co/qjXzjg7YDp

[FloMontel @FloMontel]

Dear Network, really happy and honored to take over the role of Matthias Zentgraf as EubOPEN project co-leader with Stefan Knapp and unvaluable onboarding and coordination of Oliver Krämer and Michael Sundstrom. Visit our website https://t.co/wuL41McuR2 t…https://t.co/28vkf1M246

[FloMontel @FloMontel]

Dear #Researchers, ACBI2 is a selective and orally bioavailable SMARCA2 PROTAC that leads to near-complete degradation of SMARCA2 in lung cancer xenograft models, resulting into tumor growth inhibition. Learn more on #opnMe
https://t.co/afMf0CJ66C https://t.co/rVyOQD73VM

[FloMontel @FloMontel]

Dear #Researchers, extending the vitreal half-life of proteins on the one hand and allowing the drug to penetrate well into the retina on the other hand will lead to better treatments against retinopathies. Join us on #opnMe with your vision…https://t.co/4k6BDcJp67

[FloMontel @FloMontel]

I am thrilled to share that I am starting a new position as Head of Open Science at Boehringer Ingelheim, showing the commitment of our company to foster innovative science by investing in consortia, public-private partnerships and in our leading open sci…https://t.co/FjstNkHjyc