Giancarlo Vanini

Neuroscientist interested in Sleep, Pain and Consciousness. #UmichAnes. 🇺🇾🇺🇸. BJJ enthusiast. Opinions/likes = my own.

[Giancarlo Vanini @GC_Vanini]

Ever wondered whether #sleep and wake-related neurons influence general anesthesia? Read what we learned in our new study:

Activation of Preoptic GABAergic or Glutamatergic Neurons Modulates Sleep-Wake Architecture, but Not Anesthetic State Transitions https://t.co/jV1bLOilmI

[Giancarlo Vanini @GC_Vanini]

@ESPNUruguay Nada mal. Empatamos con Inglaterra sin atacantes.

[Giancarlo Vanini @GC_Vanini]

A drink to celebrate my 20 years in Ann Arbor. Cheers!

[Giancarlo Vanini @GC_Vanini]

It's published!

In short, we found a preoptic mechanism that powerfully suppresses REM sleep (but there's much more):
https://t.co/AybZINnzrx

#sleep #sleepresearch #REMsleep #sleephomeostasis

[Giancarlo Vanini @GC_Vanini]

Today’s in-flight entertainment provided by the finest sleep/circadian colleagues!

[Giancarlo Vanini @GC_Vanini]

Brainstem pathology in human narcolepsy: Neurodegeneration in the locus coeruleus in narcoleptic humans, but not in genetically narcoleptic mice or dogs https://t.co/xD3OdflWXY

[Pierre Apostolides @pfapostolides]

(Plz repost)

I’ve been receiving some good news lately and will be hiring at all levels to expand the lab. Please get in contact if you are interested in reinforcement learning, neural plasticity, circuit dynamics, and/or hearing rehabilitation.

pierre.apostolides @ umich .edu

[Giancarlo Vanini @GC_Vanini]

Coincidentally, 2-3 days ago, I remembered a presentation at APSS (when CD players were cool, for time ref.), testing if vestibular stim. in rodents increased sleep - no effect. It got me thinking about this interesting idea tested in the preprint. 👍

[Giancarlo Vanini @GC_Vanini]

Whole-night gentle rocking improves sleep in poor sleepers with insomnia complaints. https://t.co/LUH2KLLQku

Maybe I'll start "My week's top articles"; if I do, this is this week's winner on my list! 👇

[U-M Consciousness & Psychedelics @UMconsciousness]

New article by the Michigan Psychedelic Center published in Translational Psychiatry- psilocybin induces acute reorganization of functional cortical networks in rodents. https://t.co/RbFGriXz6L

[BryanRoth @zenbrainest]

We are depositing the following mice to @MMRRC
Adgrf5-EGFP-CT-IRES-CRE
GPR123- EGFP-CT-IRES-CRE
GPR124- EGFP-CT-IRES-CRE
GPR125- EGFP-CT-IRES-CRE
Gpr133-EGFP-CT-IRES-CRE
GPR156-IRES-Cre
GPR156-mGL-IRES-Cre
GPR75-IRES-Cre
Bai1 mGL-CT-IRES-Cre
GPRC5A- EGFP-CT-IRES-ERT2-CRE
1/2

[Pierre Apostolides @pfapostolides]

these recent breakthroughs, which give hope to parents, were only possible via nationally funded basic research.

https://t.co/drYoNFVA0n <- ID’d otof as ca2+ sensor (France)

https://t.co/XR1WG0N6Cv <-central ca2+ sensors will not replace otof function, must use otof (USA)

[Giancarlo Vanini @GC_Vanini]

Just heard from a very good friend and expert neuroanatomist that the preoptic area is not hypothalamus.
Nonsense! Must be the water on the west coast. 😂

[Ubadah Sabbagh @neubadah]

Since we're talking about funding of absurd research by NIH and other federal agencies, the funded scientists:

- watching flies fuck
- giving rats massages
- spending years digging into why jellyfish glow
- tracking penguin poop from space
- using horseshoe crab blood

[Giancarlo Vanini @GC_Vanini]

@neubadah 👏👏👏

[Erik Herzog @ErikHerzog]

Happy end of Daylight Saving Time. For health, safety, and economics let’s keep Permanent Standard Time. @SRBR_Outreach @SaveStandard @ResearchSleep

[Giancarlo Vanini @GC_Vanini]

@anaclet_lab Sounds like a very optimistic person.

[Giancarlo Vanini @GC_Vanini]

@viejoolimpica La primera opinión sensata que veo desde que Suárez abrió la boca.

[Giancarlo Vanini @GC_Vanini]

NEW Preprint!

We show that preoptic glutamatergic neurons control REM sleep generation and their activation suppresses REM sleep rebound after sleep deprivation.

Regulation of REM Sleep Onset and Homeostasis by Preoptic Glutamatergic Neurons https://t.co/5FXOa1MHgx

[Giancarlo Vanini @GC_Vanini]

#Sleep and other Neuro friends heading to #SfN24, stop by Amir Jadidian's poster on Wednesday AM to hear about some (unexpected) sex-related differences in response to surgery.