Genki Terashi

Assistant Research Scientist @Purdue University My research projects: Protein structure modeling, prediction, Protein structure Modeling from cryoEM data.

[Genki Terashi @GTerashi]

Very excited to share our new paper DAQ-score, just published in @naturemethods .
Our deep learning method can estimate the local quality of the protein structure model from cryo-EM data.
DAQ is available on Google Colab:
https://t.co/1CvPpCtS1B
Paper:
https://t.co/V0RIjs9ZoT

[Kihara Laboratory @kiharalab]

The August update of DAQ-Score DB! It includes Cryo-EM protein model quality evaluations for 283,198 proteins. Figure is an example of a model with seq shifting error.
https://t.co/MmQzn1Ch8S
DAQ is easy to compute for str validation for your paper: https://t.co/oXoKmRF9Pv

[Kihara Laboratory @kiharalab]

We posted a new preprint, Prot-LAMBDA.
Unlike most protein language models, it is a pLM with an explicit encoding of protein structures. Strong performance in structure-related tasks including str prediction. https://t.co/IzGpgKtpGf

[Genki Terashi @GTerashi]

Please stop by my poster at M&M2026!
(227) DAQplugin: AI-Based Interactive Residue-Wise Validation of Protein Models for Cryo-EM Maps
I will show how real-time AI can help identify modeling errors.
Wed, Aug 5, 3:00–5:30 PM
https://t.co/hxWmsaLwB4

[Kihara Laboratory @kiharalab]

New article "Comp. approaches for protein complex modeling for intermediate res. cryo-EM maps" in Progress in Mol Biol & Translational Sci, by Joon Hong Park, @GTerashi, @d_kihara.
Introduces how to use DiffModeler and DMcloud in https://t.co/ffpc5JeKgf
https://t.co/uyppIpAgm9

[Kihara Laboratory @kiharalab]

In May (5/6 2026) we gave a webinar introducing our EM web server. The recording is now available!
Highlighted 2 recent additions:
• DAQplugin: On-the-fly structure validation for ChimeraX
• CryoZeta: A heterogeneous str modeling for proteins and DNA/RNA
https://t.co/2V5tUnH6Yx

[Genki Terashi @GTerashi]

Our EM server Webinar recording is now available on YouTube!
I presented,
CryoZeta  : Our new framework for cryo-EM structure modeling
DAQplugin : ChimeraX plugin for visualizing and analyzing DAQ scores for model quality assessment
https://t.co/iOspmgFMn2

[Genki Terashi @GTerashi]

Another new preprint of DMcloud, our cryo-EM modeling method for medium- to low-resolution maps. DMcloud uses local model fitting to place compatible protein or DNA/RNA models into enhanced EM maps. https://t.co/PdGAkGZNRK

[Genki Terashi @GTerashi]

Our recent preprint introduces DAQplugin, a ChimeraX plugin for interactive residue-wise validation of cryo-EM protein models. DAQplugin brings DAQ scoring directly into model inspection on your laptop. https://t.co/G4wZvFIdj9

[Kihara Laboratory @kiharalab]

We will host a ~30 min webinar introducing EM-server for cryo-EM structure modeling on May 6 (Wed) 12:30pm (Eastern Time). Will introduce DAQ-Score plugin & CryoZeta.
EM-Server: https://t.co/zCv7L2LFcI
Registration link: https://t.co/xx9H6Q9d0D
Hope to see you there!

[Daisuke Kihara @d_kihara]

うちのラボで作成、管理している電顕のための生体高分子のモデリングツールのウェブサイト、EM-Serverのウェビナーを行います。最近のツール２点を中心にお話します。
日本時間だと深夜１時半ですが、３０分と短いので遅くまで起きてる方は参加をお待ちしております。
https://t.co/U2P2MHU2SH

[Kihara Laboratory @kiharalab]

New collaboration paper with Bou-Abdallah lab just released! Multivalent recognition of ferritin by full-length NCOA4 enables robust ferritinophagy, Srivastava, @GTerashi et al., Protein Science
https://t.co/LaALPOaxfm

[Kihara Laboratory @kiharalab]

We have a postdoc opening. Please check
https://t.co/uZSf9Rimoa

[Genki Terashi @GTerashi]

Our new book chapter has just been published!

In this chapter, we introduce our recent work in computational structural biology and practical applications of our tools available on https://t.co/oLD3xvFnLR.
You can read the chapter here:
https://t.co/qdtNdzmV9r

[Kihara Laboratory @kiharalab]

We’ve rebuilt our Protein Function Prediction server!
New:
• Domain-PFP: self-supervised, domain-aware function prediction
• GO2Sum: converts GO terms into UniProt-style functional summaries
All methods (PFP, Phylo-PFP, ESG) now in one interface.
https://t.co/ROdnXR1Yth

[Dongwook Kim @dwkimdencoda]

Intellicule is hiring a part-time Software Engineer to advance our computational biology tools for protein design, nanobody engineering, and Cryo electron microscopy (cryo-EM) based drug discovery.
Submit resume and cover letter to [email protected]

[Kihara Laboratory @kiharalab]

New collaboration paper with the Bou-Abdallah lab at SUNY Potsdam: "Ferritin iron uptake and oxidation are dynamically modulated by nucleotide phosphate architecture via electrostatic gating", International Journal of Biological Macromolecules. https://t.co/Pu31TpKizk

[bioRxiv Bioinfo @biorxiv_bioinfo]

Accurate Macromolecular Complex Modeling for Cryo-EM with CryoZeta https://t.co/4J38NQmOZr #biorxiv_bioinfo

[Kihara Laboratory @kiharalab]

🚀 First DAQ-Score DB update of 2026 is live!
Cryo-EM protein model quality evaluations now cover 266,577 protein chains.
🔗 https://t.co/Anv8eyCiTT
🏁Check out also our New ChimeraX plugin! It lets you check DAQ scores during modeling!
https://t.co/q98zmpLoLq

[Daisuke Kihara @d_kihara]

DAQ-Score、新春アップデート第一弾🎍
ChimeraXプラグインも作りました！
モデリングしながらDAQ-Scoreをinteractiveに確認できます。ぜひ論文で構造バリデーションにご利用ください。

[Genki Terashi @GTerashi]

DAQ for ChimeraX is now released! DAQplugin computes residue-wise DAQ scores directly in ChimeraX. By comparing cryo-EM maps with atomic models, users can quickly identify potential problems, such as sequence shifts or incorrectly assigned residues.
https://t.co/yUCjzK1Va1