Liping Zhao

A microbial ecologist with over thirty years of experience on gut ecology. Nutrition, Microbiome and Health; Reference-free and Guild-based Microbiome Analysis.

[Liping Zhao @Gutzhao]

A core microbiome signature as an indicator of health https://t.co/2giss2Fibv

[Liping Zhao @Gutzhao]

Your gut microbiome is a seesaw for health! 🦠 Fiber-rich diets tip it toward Foundation Guild dominance, promoting weight control and metabolic health. Junk food fuels Pathobionts, driving obesity. #TCGScience #GutHealth

[Liping Zhao @Gutzhao]

The Two Competing Guilds (TCG) Model of Core Microbiome

[Microbiome Research Reports @MicroResRep]

🎙️We interviewed Prof. Liping Zhao (@Gutzhao), Executive Editor of #Microbiome Research Reports and Fellow of the American Academy of Microbiology.
🔗 Watch the full interview: https://t.co/KmjvQbDsYK #GutHealth #Obesity #MRR #HostMicrobe

[Microbiome Research Reports @MicroResRep]

🎙️We interviewed Prof. Liping Zhao (@Gutzhao), Executive Editor of #Microbiome Research Reports and Fellow of the American Academy of Microbiology.
🔗 Watch the full interview: https://t.co/KmjvQbDsYK #GutHealth #Obesity #MRR #HostMicrobe

[Liping Zhao @Gutzhao]

My 10 year anniversary of joining X. 还记得你何时加入 X 吗？我知道！#我的X周年纪念日

[Liping Zhao @Gutzhao]

Taxa should no longer be used as entry point analytical units for microbiome datasets. Genomes should be.

[mLife Journal @journal_mlife]

🎉Huge congratulations to our Editor-in-Chief, Dr. Jizhong Zhou, on being elected to the National Academy of Sciences! This prestigious honor recognizes his outstanding contributions to Microbial Ecology. We are proud and thrilled!
@theNASciences https://t.co/gznLIgxDzY

[CIFAR @CIFAR_News]

Researchers, including CIFAR's @Gutzhao, have developed a new method to identify crucial gut microbes essential for health. 🦠

This discovery could lead to precision nutrition and personalized therapies for managing diabetes, IBD and more.
https://t.co/4yehz8aoIF

[Gianluca Ianiro @gianluca1aniro]

Immensely grateful to all experts who contributed this piece with their expertise and efforts! @nsegata @cibiocm @GiovanniCammar9 @h_sokol @fasnicar @Siew_C_Ng @Gutzhao @PaedsRH @RaesLab @HoldGeorgina @ChristianHvas @KorenLab @TheTunLab @MireiaVallesc @mcarmen_collado @epasolli

[Liping Zhao @Gutzhao]

Meet Evo, the DNA-trained AI that creates genomes from scratch | Science | AAAS https://t.co/ELZYzXh6z9

[Liping Zhao @Gutzhao]

The third pillar of guild-based microbiome data analysis is interaction focused perspective. Co-abundance network analysis of high quality MAGs is used to identify potential guilds https://t.co/1pqm3srr8s

[Liping Zhao @Gutzhao]

The second pillar of guild-based microbiome data analysis is database independence. Each high quality MAG is given a Universal Unique Identifier (UUID) and tracked in samples across different studies for data integration and mining. https://t.co/1pqm3srr8s

[Liping Zhao @Gutzhao]

The second pillar of guild-based microbiome data analysis is database independence. Each high quality MAG is given a Universal Unique Identifier (UUID) and tracked in samples across different studies for data integration and mining. https://t.co/1pqm3srr8s

[Liping Zhao @Gutzhao]

Guild-based analysis of microbiome data has three pillars, the first is genome-specific analysis with high resolution and granularity than any taxa. High quality metagenome-assembled genomes (MAGs) are the basic features. https://t.co/1pqm3srr8s

[Liping Zhao @Gutzhao]

Guild-based analysis of microbiome data has three pillars, the first is genome-specific analysis with high resolution and granularity than any taxa. High quality metagenome-assembled genomes (MAGs) are the basic features. https://t.co/1pqm3srr8s

[Liping Zhao @Gutzhao]

What kind of analytical strategy would allow you to integrate 38 different microbiome studies and identify a set of 284 genomes of core bacteria into Two Competing Guilds as an indicator of Health: the guild-based analysis! https://t.co/EObjGdrulY

[Liping Zhao @Gutzhao]

What kind of analytical strategy would allow you to integrate 38 different microbiome studies and identify a set of 284 genomes of core bacteria into Two Competing Guilds as an indicator of Health: the guild-based analysis! https://t.co/EObjGdrulY

[Prof. Meghan Azad, PhD @MeghanAzad]

🚨New Paper Alert🚨

Our new #microbiome research, co-led with @LiatShenhav, published today in @CellCellPress!

We show that #breastfeeding "paces" gut & nasal microbiome development to prevent #asthma in the @CHILDSTUDY.

#Tweetorial 🧵

https://t.co/eeHSLIdw9Q

[Liping Zhao @Gutzhao]

@JoeAlcockMD Pathobiont Guild(PG) vs Foundation Guild (FG)

[Liping Zhao @Gutzhao]

PG, in contrast, flourishes in low-fiber, calorie-dense conditions, generating pro-inflammatory and endocrine-disrupting metabolites like endotoxins, indole, and hydrogen sulfide. https://t.co/EObjGdrulY

[GutMicrobiota Health @GMFHx]

Are we ready to define a core microbiome signature as an indicator of health?

.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:

https://t.co/11mTTpUfn1

[Liping Zhao @Gutzhao]

This concept of stability of relationships as a marker of functional significance is central to understanding the microbiome as a complex adaptive system, where the resilience of microbial networks is directly linked to host health. https://t.co/EObjGds2bw

[GutMicrobiota Health @GMFHx]

Are we ready to define a core microbiome signature as an indicator of health?

.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:

https://t.co/11mTTpUfn1

[Liping Zhao @Gutzhao]

In essence, stability within guilds like FG and PG reflects an evolutionary adaptation, enabling the microbiome to sustain functions under environmental pressures that a less connected population could not. https://t.co/EObjGdrulY

[GutMicrobiota Health @GMFHx]

Are we ready to define a core microbiome signature as an indicator of health?

.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:

https://t.co/11mTTpUfn1

[Liping Zhao @Gutzhao]

Restoring and maintaining the TCG structure in the gut microbiome is therefore essential for it to function as a dynamic regulatory interface between the host and the environment. https://t.co/EObjGdrulY

[GutMicrobiota Health @GMFHx]

Are we ready to define a core microbiome signature as an indicator of health?

.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:

https://t.co/11mTTpUfn1

[Liping Zhao @Gutzhao]

It illustrates how dietary choices shift the balance toward either health or dysfunction, suggesting that restoring FG dominance through fiber-rich diets could recalibrate this balance, realigning it with the microbiome’s evolutionary purpose. https://t.co/EObjGdrulY

[GutMicrobiota Health @GMFHx]

Are we ready to define a core microbiome signature as an indicator of health?

.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:

https://t.co/11mTTpUfn1

[Liping Zhao @Gutzhao]

Thus, the stable competition between FG and PG is fundamental to the microbiome’s role as an adaptive nutrient sensor. https://t.co/EObjGds2bw

[GutMicrobiota Health @GMFHx]

Are we ready to define a core microbiome signature as an indicator of health?

.@Gutzhao et al. suggest a stable interaction-focused approach to enhance our understanding of the fundamental structure of the gut microbiome:

https://t.co/11mTTpUfn1