You can read our new study, out now in @JCI_Insight! (https://t.co/RPG0UHKpKp) We examine how expression of a STING gain-of-function (GOF) mutation in radioresistant host cells results in the development of lymphocyte autoimmunity. Some highlights from our study: (1/7)
#InterferonsFriendsOrFoes?! @labs_mann@NordmannThierry French Ji &co using single cell proteomics identify @Nature an IFN signature in macrophages & keratinocytes KCs in a fatal #skin disease showing that JAK inhibition prevents KC death, curing patients https://t.co/coP5y5CjIG
https://t.co/g4NGgIGbXz
I hope this is a helpful review!
Appreciate the opportunity to co-write this review in @NatImmunol with my mentor @FitzgeraldKate. Thanks to all the reviewers' comments which significantly elevated our work and thanks to the unsung artists for their art!
An autoinflammatory syndrome-associated STING mutation supports formation of germinal centers containing immunocompetent cells in the lungs of irradiated mice following BMT- https://t.co/kQEiBi6QXM
Study from@ImmunoKevin and colleagues @kchianggg@FitzgeraldKate@UMassChanPII
Our paper introducing the concept of 'defensive tolerance' officially came out in @jclinicalinvest. I would like to thank all our collaborators, as well as Drs. Molinari and Cravedi for their wonderful accompanying commentary. #defensivetolerance https://t.co/VH93FYG3sx
You can read our new study, out now in @JCI_Insight! (https://t.co/RPG0UHKpKp) We examine how expression of a STING gain-of-function (GOF) mutation in radioresistant host cells results in the development of lymphocyte autoimmunity. Some highlights from our study: (1/7)
I also want to acknowledge Dr. Kerstin Nundel, who not only contributed to this study but has also been a constant and amazing mentor throughout my PhD training. Thank you also to our collaborators, Dr. PJ Utz and Xihui Yin for their generous help and support.