π Among US #ClinicalTrial informed consent forms posted after the Dobbs decision, only about one-third included certificates of confidentiality, which may expose patients to legal and privacy risks in states with restrictive abortion laws.
https://t.co/zdhacCdueP
π Among transgender and gender-diverse adults in Sweden, prevalence of most #GenderAffirming medical treatments was low, future treatment need was common, and dissatisfaction with past treatment decisions was very low.
https://t.co/KK7HzOn7Px
π Among adults with #Diabetes, current injectable #GLP1 receptor agonist use was lower in patients with a history of #Cancer than in those without a cancer history, despite higher prevalence of cardiovascular and kidney disease.
https://t.co/KEsxSYKD6b
π Among US adults eligible for obesity treatment, oral #Semaglutide uptake increased rapidly after approval for #Obesity and approached injectable semaglutide within 3 months. More than half of initiators had no prior semaglutide use.
https://t.co/Dg0bf7wdo9
π In adults with #Type2Diabetes who had poor glycemic control or recent hypoglycemia, sustained use of real-time #ContinuousGlucoseMonitoring was associated with durable reductions in hemoglobin A1c over 3 year.
https://t.co/Wil9ANYSPf
π₯ Among adults evaluating surrogate decisions for seriously ill older patients, the presence of #Dementia was associated with a lower likelihood of recommending life-sustaining treatments.
https://t.co/zFGcijPDq6
π In Australia, removal of prescribing and dispensing restrictions on #Mifepristone-misoprostol was associated with more pharmacies ordering the medication and broader geographic access to medication abortion.
https://t.co/E0Q4sq9Wup
π Among American Indian and Alaska Native beneficiaries with #Cancer in traditional Medicare, mortality was nearly double that of the overall Medicare cancer population, with higher spending and greater inpatient care use.
https://t.co/P26OCFWa0Q
Among adolescents and young adults with hereditary #Cancer predisposition, a chatbot-based communication tool used after a clinic visit improved understanding of cancer risk by age 30 years compared with a clinic visit alone, without increased distress.
https://t.co/vF1zscrodh
π£ This JAMA+ Trials Theme of the Month examines how #pragmatic clinical trials are intended to generate evidence for real-world clinical decisions without sacrificing research rigor.
π¬ Learn more about this trial and subscribe to the newsletter: https://t.co/phah3FEK04
Among veterans seeking primary care for #LowBackPain, a sequenced care pathway was not superior to a pain navigator pathway for improving pain interference or physical function at 3 months.
π https://t.co/fsRT4c3xik
π’ Share your opinion: New JAMA+ Trials Poll!
How many clinical trials that claim to be "pragmatic" actually provide useful evidence for real-world decision-making?
π Vote now and join the discussion: https://t.co/Jae1cg4z9Y
#ClinicalTrials#Research#Evidence
π Integrating #SmokingCessation treatment into #LungCancerScreening was cost-saving vs screening alone, with higher-intensity pharmacotherapy and counseling associated with the greatest long-term health gains.
https://t.co/M724OVSwAD
π Among infants who were tested for respiratory syncytial virus (#RSV) in 2 Canadian provinces, receipt of #Nirsevimab was associated with lower risk of RSV-related emergency department visits, hospitalization, and intensive care unit admission.
https://t.co/64kvwKsNWf
π Among patients at #HRSA health centers, #FoodInsecurity was associated with more referrals to food assistance, but more than one-third of food-insecure patients reported receiving neither SNAP or WIC nor a referral.
https://t.co/pyCWsouZxG
π Among older inpatients with #Malnutrition at admission, implementation of a nutrition clinical framework was associated with lower in-hospital mortality and shorter length of stay.
https://t.co/EHHGD8JTAh
π§ In #MajorDepressiveDisorder, gray matter volume trajectories over 10 years were associated with cumulative illness burden rather than diagnosis alone or acute symptom fluctuations.
https://t.co/MkVXS3af46
π Among survivors of #BreastCancer in a longitudinal cohort, nonresponsiveness increased over time and was associated with social vulnerability, unhealthy behaviors, symptom burden, and enrollment at smaller centers.
https://t.co/Y4vLAFnTDK
π Perceived good death priorities differed across settings, while patient-caregiver differences were generally small, supporting culturally sensitive #PalliativeCare that reflects both shared and setting-specific end-of-life values.
https://t.co/9yBY38q0Bi
Among Denmark children, a history of #FebrileSeizures was reassuringly associated with school test performances largely similar to that of unaffected peers. Children with many recurrences or later epilepsy may benefit from additional educational support.
https://t.co/8TVwdjn9KA