Journal of Physiology

The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms

[Journal of Physiology @JPhysiol]

In this study, Fernanda Sanhueza-Olivare (@uchile) and colleagues performed vascular remodelling in a mouse model of heart failure with preserved ejection fraction💻️ 🫀

Read the #research 👇️

https://t.co/NJ6ULyuUNq

[Journal of Physiology @JPhysiol]

Ignacia González & Rodrigo Maldonado-Agurto (@ufinisterrae) examine the role of cellular #senescence in #endothelial dysfunction and #vascular remodelling in arteriovenous fistula maturation 🫀 🔬

Read the review 👇️
https://t.co/uaaD7capKo

[Journal of Physiology @JPhysiol]

'Dysregulation of #neural tube vascular development as an aetiological factor in autism spectrum disorder: Insights from valproic acid exposure'🫀

Read the review by Jorge Manzo (@UVeracruzanaMx) and colleagues 👇️

https://t.co/DoK5F1TXC1

[Journal of Physiology @JPhysiol]

Ameyalli Gómez-Ilescas and Patricia Pelufo Silveira (@mcgillu) examine early adversity and the comorbidity between #metabolic disease and #psychopathology ✍️ 🧠

Read the review 👇️
https://t.co/dRrDfslpsr

[Journal of Physiology @JPhysiol]

'Metabolic heterogeneity of endothelial cells: potential for tissue-targeted therapies in diabetic vascular complications'

Aryan Y. Sarnaik examines the work of McAleese et al. (2026) in this #JournalClub article ✍️

🔗 https://t.co/6FId8aykFA

[Journal of Physiology @JPhysiol]

Yifeng Dai (@umcg) and colleagues examined the differential effect of #lead and #cadmium on mitochondrial function and NLRP3 inflammasome activation in human #trophoblast 🔬 💉

Read the #Research 👇️

🔗 https://t.co/Updast6guk

[Journal of Physiology @JPhysiol]

'Reducing the negative effects of calciprotein particles on endothelial cells in chronic kidney disease: A promising non-pharmaceutical approach'

Stephanie Lapierre-Nguyen & Jigar Gosalia (@CUAnschutz) examine the work of Feenstra et al. (2026) ✍️

🔗 https://t.co/pHSbf3Qn2N

[Journal of Physiology @JPhysiol]

'Pathophysiological features of pre-clinical HFrEF and HFpEF models'

Alexa N. King (@uofg) examines the work of Méndez-Fernández et al. (2026) in this #JournalClub article ✍️

🔗 https://t.co/V5Ok1AYwwi

[Journal of Physiology @JPhysiol]

In this study, Lian Feenstra (@umcg) and colleagues observed that calciprotein particle-induced #calcium overload triggers #mitochondrial dysfunction in endothelial cells 🧫 🔬

Read the #research 👇️

📜 https://t.co/wfFKg0TeVw

[Journal of Physiology @JPhysiol]

'Macrophage lipid accumulation and inflammation: How aquaporin 3 regulates metabolic adaptation to palmitic acid in cardiometabolic diseases'

Mariana Camões (@UnivdeCoimbra) et al. examine the work of Luévano-Martinez et al. (2026) ✍️

🔗 https://t.co/3P0hbZVCfD

[Journal of Physiology @JPhysiol]

'The RhoA guanine exchange factor ABR: a glucose-sensitive mediator of actin reorganization in feto-placental arterial #endothelial cells altered by gestational #diabetes mellitus' 🔎

Read the #research from Silvija Tokic (@MedUniGraz) et al. 👇️

🔗 https://t.co/NKyt3r5dph

[Journal of Physiology @JPhysiol]

In this review, Macarena Lépez (@FacMedicinaUC) and colleagues examine the impact of maternal #obesity on fetal #myeloid immune cells and explores potential mechanisms that underlie early-life immune programming 🔬 📜

Read it here👇️
https://t.co/2Ke4tMlbP4

[Journal of Physiology @JPhysiol]

'Methodological evaluation of muscle oxidative stress in normotensive and hypertensive individuals: Ageing-related'

João Pedro Floriano and Alisson Luiz da Rocha (@usponline) assess the work of Speer et al. (2026) in this #JournalClub article ✍️

🔗 https://t.co/fL0j9pPEK8

[Journal of Physiology @JPhysiol]

In this review, Amanda A. de Oliveira (@UAlberta) and co-authors discuss excessive #hypercholesterolaemia during #pregnancy as a risk factor for endothelial dysfunction in pre-eclampsia 🔎 🔬

Read it here👇️
https://t.co/JJwAzFOQuK

[Journal of Physiology @JPhysiol]

'Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment #epithelial cells with #hypertensive phenotype' 🫒 🧬

Read the #Research by Álvaro Santana-Garrido (@fafarsevilla) and colleagues here👇️
https://t.co/aWTrbeNlnZ

[Journal of Physiology @JPhysiol]

#Research by Esthefanny Escudero-Guevara (@ubbchile) et al. identified that #stroke severity shapes extracellular vesicle profiles and their impact on the cerebral #endothelial cells 🧠 🔬

Read the study👇️
https://t.co/vThnX9G3wt

[Journal of Physiology @JPhysiol]

In this review, Yuri Sanchez-Martinez and colleagues (@udes_oficial) detail the cellular and molecular mechanisms by which the progressive changes associated with #ageing can alter healthy skeletal #muscle and #endothelial function 🧑‍⚕️ 🔎

Read it here:
https://t.co/07J2C7oxGm

[Journal of Physiology @JPhysiol]

Consuelo Pasten (@uandes) and colleagues observed that the protective effect of 1400W against #ischaemia and #reperfusion injury is countered by transient medullary #kidney endothelial dysregulation🔎 🔬

Read the study👇️
https://t.co/kHsl1ytja8

[Journal of Physiology @JPhysiol]

#Research by Sergiy Klid (@universitatURV) and colleagues concludes that impaired #angiogenesis in gestational #diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation 🔬 💉

Read the study👇️
https://t.co/NcafdiP8zj

[Journal of Physiology @JPhysiol]

'Distinguishing #pathophysiological features of #heart failure with reduced and preserved ejection fraction: A comparative analysis of two mouse models'

Read the #Research by Abraham Méndez-Fernández (@TecSaludMX) and colleagues 👇️
🔗 https://t.co/e6pgwtDAUt