Ké℣ɨɳ Ͼ ❁

sharing the view from my seat at the end of the world 🥂

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

me: serving up 🔥 tweets
my friends on twitter:

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

From the same people who brought you the classic "If They Haven't Done Anything Wrong, They Should Have Nothing to be Afraid of" comes their new hit single, "Fuck Tha FBI"

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@vynnari the quotes are doing a lot of heavy lifting there. her frequency/soul is in an exoswarm body, and exoswarm are largely regarded as alive and participate in the biological ecosystem as living beings; eating, sleeping, etc. she's not in a living human body though, for sure.

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

i would agree, one of, if not the, coolest games i've played as well

[kaiiduru @kaiii472699]

Tenz shares his opinion on genshin vs wuwa

#wutheringwaves #genshinimpact

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@CptFluffy25 @DovySimuMMA I was thinking 10 also & probably gets subbed—dope pic btw, hope the pulls went well ✌️

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@katsudumps Scour the interwebs for leaks and await the next update. And maybe go outside… maybe.

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@zsstrr How I’ve felt for L-R and if the pattern follows, the writing for at least a couple of them will probably win you over lol

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@InfernoZard10 Def giratina. Lunala is probably good too, but mewtwo has the coverage to flatten him with those 4x weaknesses, so giratina feels more reliable

[Peché Africa 🇿🇦 @pmcafrica]

Bro said... hold my glasses 👓

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@WuWa_Ani_Info 2.0 in general, but the alvinoleum with Carty and Cantarella (can’t recall the tenth place value) felt like the biggest jump in quality to me, really ruining pretty much every game I’ve played/ tried since 😂

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@WuWa_Ani_Info Aemeath = Carty > Jinhsi. Gun to my head, I personally prefer Carty/ Rinicita’s whole arc for the more elaborate slow burn, but it didn’t have the same emotional punch as Aemeath/ Lahai-Roi. Can’t go wrong imo, & can’t wait for what’s next

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@DovySimuMMA Don’t know him personally but already tired of the gimmick—it’s corny and childish plus makes the sport look cheap and dishonorable. His last fight was entertaining though, gotta give him that.

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@FlipMeAC How much changes for you on a durin-less account?

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@WuWa_Ani_Info I choose… yes.

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@KingRock7x @HappyPunch A lot of us in that boat rn, I wish they featured the time more in marketing since it was so far off the norm

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

To those able to participate, hopefully more to come as I doubt a single day will fix much, but a meaningful step in the right direction: https://t.co/PG2u3Yexbu

[Paul F. Austin @PaulAustin3w]

We can now watch psilocybin grow new brain connections in real time.

Not metaphorically. Not "neuroplasticity" as a vague buzzword. Actual, physical structures — dendritic spines — sprouting from cortical neurons within 24 hours of a single dose.

A team at Yale used chronic two-photon microscopy to image individual dendritic spines on layer 5 pyramidal neurons in the medial frontal cortex of living mice.

Before psilocybin. After psilocybin. Same neurons. Same spines. Day after day.

And here's what they found:

A single dose of psilocybin produced a ~10% increase in spine density and spine size. New spines began forming within 24 hours. Most of these new connections were still there a month later.

That last part matters most.

Psilocybin has a half-life of about 3 hours. The molecule is gone by dinner. But the structural changes it triggers persist for at least 34 days (and likely far longer).

This is the biological explanation for something clinicians have observed for years: a single psilocybin session producing therapeutic benefits that last months. The drug disappears, but the architecture it built does not.

There's a critical mechanistic detail. When researchers pre-treated with ketanserin — a 5-HT2A receptor antagonist — the spine growth was completely blocked. This confirms that structural remodeling depends on activation of the serotonin 2A receptor. The same receptor responsible for the psychedelic experience itself.

A 2025 follow-up from the same lab went further. Using rabies tracing to map brain-wide inputs to these new spines, they discovered psilocybin's rewiring is network-specific. It selectively strengthens inputs from perceptual and default mode network regions, the same networks implicated in self-referential processing, rumination, and depression.

It doesn't just grow connections randomly. It grows the RIGHT ones.

Here's what this means for practitioners:

The window after a psychedelic experience isn't just psychological. It's structural. New dendritic spines form and stabilize in the days and weeks following a session.

Integration practices — therapy, journaling, somatic work, meditation, breathwork — aren't just processing insights. They may be reinforcing which of these new physical connections survive.

You're not just supporting someone's mental model. You're supporting their neural architecture.

Think about what that reframes. The integration period isn't a nice-to-have. It's a biological imperative. Those new spines either stabilize into lasting connections or get pruned. The environment, practices, and support during that window may determine which.

We're not just learning that psilocybin works. We're watching exactly how it works, at the level of individual synapses.

The implications for how we design protocols, structure integration, and time follow-up sessions are enormous.

What do you make of this research? Is psilocybin the miracle drug that science makes it out to be?

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

Got a letter from my cousin and it brought a much-needed smile to my face today—what an honor to be a desired companion to a Pokemon tournament, of all things. AND he knew my favorite! 🥹

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

@HawkEmDownChris

[Ké℣ɨɳ Ͼ ❁ @KevinVGC]

(an excerpt, not the entire poem)