Louis-Félix Nothias

Group Leader at @HolobiomicsLab - @CNRS @Universite_CotedAzur @Nice_Chemistry - Co-coordinator of

[Louis-Félix Nothias @LF_Nothias]

10 months ago @Martin993886460 joined HolobiomicsLab to build agentic AI for science. We just released Mimosa (preprint, 30 March 2026) — an open framework where multi-agent workflows evolve to solve scientific problems.

https://t.co/3mdz721pjH

[Louis-Félix Nothias @LF_Nothias]

At the same time, this was very important to have discussions with colleagues on the short/long-term challenges/risks. There are many and we should anticipate. More on: https://t.co/G6u5TKyhrE

[Louis-Félix Nothias @LF_Nothias]

Thanks and congratulations to Justin J.J. van der Hooft, Soha Hassoun Tomáš Pluskal Stacey Reinke for organizing this landmark #Dagstuhl Computational Metabolomics seminar 26181 !

What an amazing four days with many fruitful discussions and interactions

[Louis-Félix Nothias @LF_Nothias]

... like Mimosa-AI (https://t.co/LI19oE1L1R) and those from MetaboLinkAI More generally, I was pleased to notice the general interest in agentic-AI and admission of its transformative potential for metabolomics and science - which wasn't that widely recognized 2 years ago.

[Louis-Félix Nothias @LF_Nothias]

HolobiomicsLab (@CNRS @CNRSchimie @NiceChemistry @Univ_CotedAzur / 3iA Côte d'Azur) with @Inria @wimmics, within MetaboLinkAI (@AgenceRecherche / @snsf_ch).

@LF_Nothias @Martin993886460 @elisejdumont @fabien_gandon

[Louis-Félix Nothias @LF_Nothias]

10 months ago @Martin993886460 joined HolobiomicsLab to build agentic AI for science. We just released Mimosa (preprint, 30 March 2026) — an open framework where multi-agent workflows evolve to solve scientific problems.

https://t.co/3mdz721pjH

[Louis-Félix Nothias @LF_Nothias]

Code + preprint:
https://t.co/67ugQh0Ogn
https://t.co/DxsOkeRtO1
https://t.co/iuK5jcuLSQ

Both Mimosa and Toolomics open source under Apache 2.0.

[Louis-Félix Nothias @LF_Nothias]

Super happy to see our team work with Philipp Ternes @rschmid1789 @Pdorrestein1 and coll.. It was a quite insightful to computationally investigate contributions of chromatographic-MS conditions and explore metabolites/microbes through machine learning and multi-omics graph.

[Akos T. Kovacs @EvolvedBiofilm]

Functional metabolomics of the human scalp: a metabolic niche for Staphylococcus epidermidis

@mSystemsJ from Philipp Ternes
with @Pdorrestein1

https://t.co/Oylb3X8YQH

[mzmine @mzmine_project]

Register now! Prague Computational Mass Spectrometry Workshop, April 15-17, 2024, Prague, Czechia.
Learn from the developers and power users of @mzmine_project, SIRIUS, #matchms, @TheLOTUSInitia1, @GNPS_UCSD and discuss how we can move the field forward... https://t.co/rcGk6c6TOh

[SteffenHeu @HeuSteffen]

Acquisition of meaningful MS2s in MALDI imaging is challenging.
SIMSEF systematically schedules MS2s across a sample, raising confidence in annotations within @mzmine_project.

Thanks to all coauthors, @rschmid1789,@BrukerMassSpec for making this possible

https://t.co/fZQHw9OeZ1

[Pieter Dorrestein @Pdorrestein1]

Wonderful thesis defense by Irena on metabolomics in Dissolved Organic matter. This is one of the most complex matrices to analyze by mass spec. Just so so many molecules present. @LF_Nothias @boeckerlab @GNPS_UCSD and many other people made the discoveries possible.

[Louis-Félix Nothias @LF_Nothias]

@kyobinkang @BeniddirM @thermofisher Yes. It is shared between the Wolfender and Rudaz labs. Indeed, the 240 is quite a stretch in the price tag.