RESEARCH | Yao, Shao, Shan, Wu et al. (Zhejiang U)
A distinct lipid-laden subset of monocyte-derived macrophages regulates hepatocyte proliferation and liver regeneration in injured livers, via CD36-mediated signalling.
https://t.co/QI3b4LJyZX
Happy Sunday! Here are the most recent issues of bims-metlip, chock-full of new analytical and computational methods for #metabolomics and #lipidomics
https://t.co/ktn0e18Jim
https://t.co/DPG6tqgUdr
Brought to you in collaboration with @Bims_BiomedNews
#NatMetabPicks | In @Nature led by RK Jain, @geochurch & @mvh_lab (@Harvard)
This work highlights the complexity of metabolic dependencies in metastatic site selection.
https://t.co/yQSY9ZxxAc
An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. https://t.co/3d6pYrcAJ5
Douglas Hanahan
@CellCellPress
For nearly a century, we’ve asked: why do proliferating cells ferment glucose even when O2 is around? I’m thrilled to share our latest work @NatMetabolism, led by @thebioKIMist! Leveraging conditional essentiality in HPLM, we propose a provocative new answer to this classic Q 🧵
🆕Paper in @NatureGenet from Georgios Kanellos in @owen_sansom's lab: Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation https://t.co/Ht4RFtdv9W
Online Now: Hypoxia-induced ribosomal RNA modifications in the peptidyl-transferase center contribute to anaerobic growth of bacteria https://t.co/dQW1geDuw7
RESEARCH | F Kaluba, EC Lien et al. (@VAInstitute):
Cancer cells can reroute ketones to produce cytosolic acetyl-CoA and support tumour growth.
https://t.co/y0uGLJZD3O
📢Last weeks #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️⬇️
https://t.co/uRFtpjz39g
Interesting finding:
Cytochrome c oxidase dependent respiration is essential for T cell activation, proliferation and memory formation
📢Last weeks #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️⬇️
https://t.co/hMdfwUKac6
A huge collection inside!
Interesting finding:
Itaconate transport across the plasma membrane and Salmonella-containing vacuole via MCT1/4 modulates macrophage antibacterial activity
📢Last 2 weeks of #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️
https://t.co/u7ZQxQZUxi
https://t.co/s6dLENtnyE
Exciting to have a paper in the collection!
An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice
Great work from Suzan Ber and Alessandro Esposito regarding the metabolic reprogramming driven by different KRAS mutation in colorectal cancer. Thank you for involving me in this cool project! https://t.co/OHG0Ip0IBb