Matt Feinstein

Cardiologist & Researcher in Cardiometabolic Inflammation — Chief of Cardiology and Cardiovascular Institute Co-Director @ Indiana U SOM / IUHealth

[Matt Feinstein @MattFeinsteinMD]

Thrilled to start 1/2026 as Chief of CV Medicine and Co-Director of the CV Institute @IUMedSchool / @IU_Health! Grateful for lifelong friends, colleagues, trainees @ NUFSM & continuing collabs. Excited for what's to come at IUSM/IUH! @IUSMDeptMed @saraj_pereira @IUCVInstitute

[IU School of Medicine @IUMedSchool]

Sara J. Pereira, MD, and Matthew J. Feinstein, MD, will lead IU’s Cardiovascular Institute as co-directors, driving innovation in heart health and research:
https://t.co/nZY6U0Ssu9

[Circulation @CircAHA]

Lifestyle intervention-induced visceral adipose tissue (VAT) loss may persist despite weight regain and confer lasting cardiometabolic benefits: VAT loss, not weight loss, may be the key target for durable cardiometabolic health. https://t.co/uHef45YF0d

[AdaWeinstock @AWeinstock]

Our international group is absolutely ecstatic and SO grateful to receive this award from @FondationLeducq
Stay tuned for some amazing science

@ChiaraGiannare1 @ryden_mikael @edwardfisher20

https://t.co/zjk79DrhiF

[Waggoner Lab @LabWaggoner]

Review @SciImmunology
The transcriptional and epigenetic regulation of macrophage differentiation, specialization, and activation in health and disease
https://t.co/Woxrw6xR6N

[Matt Feinstein @MattFeinsteinMD]

👏🏼 kudos to recently minted MDs
@NagasakaReina @HAvgousti for leading this pilot effort borne out of a simple clinical question - how might PCI be affecting acute neutrophil responses.
Great multidisciplinary collaboration!
@SumaginLab @thorplab @jessquagginsmi1 @SchimmelHeart

[EdT @thorplab]

Acute effects of percutaneous coronary intervention on neutrophil activation and maturity markers in coronary and peripheral circulation - PubMed https://t.co/4H6HXj5TTD

[Stephanie Xie @stephxie]

✨ Thrilled to share our new publication in Nature.
We define an “inflammatory memory” HSC state (HSC‑iM), linking lifelong inflammatory exposure to aging and disease.
📄 Article: https://t.co/7OSZ7uNZHi
Grateful to an incredible team and global collaborators 💚💙

[Matt Feinstein @MattFeinsteinMD]

Great to have you @shivkumarmd - enjoyed the conversations on past, present, and future!

[Kalyanam Shivkumar MD PhD @shivkumarmd]

Thank you @MattFeinsteinMD @IUCVInstitute @IUMedSchool @IUIntMed for a truly memorable visit. Indiana has given us beloved teachers (Drs. Zipes, Feigenbaum, Miler) to the world of cardiology and of course our own Coach Wooden to the world!

[Matt Feinstein @MattFeinsteinMD]

Special day here at @IUCVInstitute @IUMedSchool @IUIntMed !
✅Grateful to host the inspiring @shivkumarmd as Zipes visiting professor
✅Honoring John Miller and Anjan Sinha as the inaugural Zipes and Feigenbaum Distinguished Physician-Educators, with namesakes in attendance!

[Indiana Surgery -Indiana Univ School of Medicine @IU_Surgery]

Congratulations to Andrew Gonzalez, MD, JD, MPH, FACS, on receiving national recognition for his National Institutes of Health-funded research focused on developing an intelligent clinical decision support system for peripheral arterial disease. His proposal was recognized as an outstanding submission and will support continued research and innovation in vascular care. 🔬🩺

Image description: graphic congratulating Andrew Gonzalez, MD, JD, MPH, FACS, on receiving the 2026 SVS Foundation/American College of Surgeons Mentored Patient-Oriented Research Career Development Award, featuring his headshot and IU School of Medicine Department of Surgery branding.

IU Surgery | IU Surgery Research | IU Vascular Surgery |

[Circulation @CircAHA]

#JustPublished: Lp(a), Evolocumab & First Major Coronary Event https://t.co/vTZNqlOR3f

[Kyle G Daniels @ScienceKyle]

🚨What if we could reliably program macrophage polarization state?🚨

https://t.co/6qGxuHptQq

Macrophages are highly plastic immune cells that perform critical functions by polarizing into distinct cellular states. The polarization state of macrophages can substantially influences the progression of cancers, infections, and autoimmunity. (1/11)

[Matt Feinstein @MattFeinsteinMD]

@lifterscientist @AHAScience @AHAMeetings @rosenzweig_a @JSawallaGusehMD @chansteve73 @thorplab @IUCVInstitute @ParthaDuttaLab @IUMedSchool @NUFeinbergMed @MGH_CLP @UMichMedSchool @PittVMI Never! We have a great program on this in a couple of weeks. Check it out: https://t.co/4nI38VcKEV

[Matt Feinstein @MattFeinsteinMD]

Great time in Ann Arbor for the our @AHAScience @AHAMeetings Inflammation SFRN! Outstanding engagement from all Centers - NU/IU/CSU, Pitt/PAMU, and UM/MGH/Oakland. Thanks @rosenzweig_a for hosting! @JSawallaGusehMD @chansteve73 @thorplab @IUCVInstitute @ParthaDuttaLab + more

[Leng Han @lenghan_bioinfo]

Happy to share our latest publication https://t.co/udnudJfhpy
Led by outstanding @HereYuan @JingwenYang_, and wonderful collaboration with @CardioOncology Douglas Johnson, @DrYanyanLou! @IUIndianapolis @IUCancerCenter @HealthIusm60944

[Matt Feinstein @MattFeinsteinMD]

Great to have @chansteve73 @PittVMI in Indy! Fun catching up and talking all things inflammation as we work on @AHAScience SFRN collaborations and beyond. @IUCVInstitute @IUMedSchool @IUIntMed

[ATVB: An AHA Journal @atvbahajournals]

Anti-inflammatory therapy targeting interleukin 6 receptor attenuate platelet activation in patients with myocardial infarction @KasparBroch @TuvaBDahl @BenteHalvo84025 @Halvorsen Lab_RIIM
https://t.co/WeAH5ftaQb

[Indiana Surgery -Indiana Univ School of Medicine @IU_Surgery]

Welcome to IU Surgery, Marc Gerdisch, MD, FACS, FACC, FHRS. 👏

Gerdisch joined our Division of Cardiothoracic Surgery on April 1, bringing nearly 30 years of experience and a global reputation in complex cardiac care. We’re excited to welcome his leadership and expertise in research, surgical training and quality care. 

#IUCardiothoracicSurgery #IUSurgeryFaculty #IUSchoolofMedicine

[Javid Moslehi @CardioOncology]

Our vision for the cardio-immunology program at UCSF! We will be hiring new post-doctoral fellows and physicians in this space. Stay tuned for more information! @UCSFCardiology @immunox

[Karl Bilimoria @kbilimoria]

Celebrating our new faculty member, Marc Gerdisch, leading the American Heart Association Ball 2026. Strong showing from the @iu_health and the Cardiovascular Institute leadership teams! @IU_Surgery @IU_Health @IUMedSchool

[Ruslan Rust @rust_ruslan]

New preprint: mass cytometry across 351 blood + CSF samples, two cohorts, full AD continuum.

Peripheral immune signatures (pAkt in naïve T killer cells, pPLCγ2 in granulocytes) emerge in preclinical AD, before plasma ptau217, CSF ptau181, and DCE-MRI BBB disruption. Not seen in FTLD or MS.

I guess this suggests that immune changes are among the earliest detectable events in AD. Might have implications for early biomarkers.

https://t.co/obFjpMhbKc

[Nature Reviews Cardiology @NatRevCardiol]

New online! Reframing atherothrombosis through the inflammation hypothesis https://t.co/SdX5OtqqwX