Have been looking a lot at astrocytes recently; these guys are workaholics! Check the ones handling 2 blood vessels at the same time. One disruption and the blood-brain barrier can be compromised! This one is from the human brain. Nuclei 🔵Dapi, Astrocytes 🟠Gfap. @zeiss_micro
Saw today these astrocytes interacting with an amyloid plaque in the brain of an #Alzheimer Disease patient, in the prefrontal cortex. Beautiful and scary!🔬(🟠astrocytes-gfap,🔵b-amyloid-D3D2N)
Interesting approach for acne treatment: engineer bacteria to work like Accutane, but locally (and without all the nasty side effects)!
Modified C. Acnes bacteria secrete NGAL to kill sebocytes & thus sebum production. They engraft on mice skin & produce NGAL there.
Scientists from @ljiresearch and @biogen found blocking the TWEAK cytokine reduces #psoriasis gene expression and skin inflammation in mice, pointing to alternative treatment.
Check out the 2021 study: https://t.co/6al9iZvStM #WeekendReads