Oncogene Journal

Oncogene aims to make substantial advances in our knowledge of processes that contribute to cancer by publishing outstanding research.

[Oncogene Journal @oncogenejournal]

Beyond its non-coding role, the lncRNA GSEC produces GESP, a tumour-promoting polypeptide that recruits c-Myc to repress NDRG1, thereby maintaining an undifferentiated state and accelerating colorectal cancer progression.
https://t.co/yom3VzPqVb

[Oncogene Journal @oncogenejournal]

New research identifies Neuromedin U (NMU) as a key driver of immune suppression in neuroendocrine prostate cancer. Read now.
https://t.co/TZsMRkcMNR

[Oncogene Journal @oncogenejournal]

A study providing a spatial proteomic map of ectopic lymphoid-like structures in metastatic #ColorectalCancer and identifying a tertiary lymphoid structures-based signature with strong potential for predicting #metastasis and clinical outcomes

https://t.co/8HKOd3by0g

[Oncogene Journal @oncogenejournal]

PER2 functional deficiency-driven CLOCK-HER2/CD47 axis promotes #BreastCancer susceptibility and #tumour immunosuppression

https://t.co/UD6rxQBIT2

#OpenAccess

[Oncogene Journal @oncogenejournal]

🔬Study identifying DNA methyltransferase 1 (#DNMT1) as a critical epigenetic driver of triple-negative #BreastCancer proliferation and metastasis

https://t.co/cJrwEtS6Wk

#TNBC #OpenAccess

[Oncogene Journal @oncogenejournal]

RXR–MYLIP–LDLR axis linking cholesterol metabolism to apoptotic susceptibility

https://t.co/iaqs4WPgNv

[Oncogene Journal @oncogenejournal]

A mechanistic insight into lineage plasticity in #LiverCancer

🔬https://t.co/6V3wGjwkI6

#OpenAccess

[Oncogene Journal @oncogenejournal]

A new study from @Adductor and co-workers links a #chemotherapy-regulated interferon signalling program to incomplete pathological responses in #ColorectalCancer.

#OpenAccess here 👉https://t.co/4lwP4usdps

[Oncogene Journal @oncogenejournal]

Blocking PINK1/Parkin-mediated #mitophagy makes #BreastCancer cells more vulnerable to cuproptosis, revealing a promising strategy to boost Elesclomol-based anticancer therapy.

[Oncogene Journal @oncogenejournal]

p53–RB signalling imbalance triggers tumour immunity during the early stages of oral carcinogenesis

https://t.co/zsq3M2mX4q

#HNSCC

[Oncogene Journal @oncogenejournal]

In our latest issue @RKateHyde & co-workers show that the Inversion 16 fusion gene, CBFB::MYH11, is required for the survival of #AML cells in the blood and spleen, but not the bone marrow.

👉https://t.co/zEm5hJiHPM

[Oncogene Journal @oncogenejournal]

An insight into the mechanism of immune checkpoint blockade resistance in #GastricCancer

https://t.co/DsaIiSXi5z

[Oncogene Journal @oncogenejournal]

Bispecific ANXA2/CD147 CAR-T cell - a promising new strategy for the immunotherapy of #osteosarcoma 🦴

https://t.co/ewUmpt6QRL

[Oncogene Journal @oncogenejournal]

A novel and fundamental role for nuclear amphiregulin in heterochromatin maintenance and genome stability in proliferating mammary epithelial cells

👉https://t.co/GAWd1JXhFE

[Oncogene Journal @oncogenejournal]

SETDB1 drives tumour progression and immune escape in endometrial cancer

https://t.co/XGLMmP111m

#OpenAccess

[Oncogene Journal @oncogenejournal]

New mechanistic insights for understanding the oncogenic role of SKP2 in shaping the prostatic #microenvironment during early carcinogenesis

🔎https://t.co/QUez7tgj3I

[Oncogene Journal @oncogenejournal]

A hidden epigenetic circuit may be driving abiraterone #resistance in CRPC: targeting the ELF3/JUNB-WNT11 pathway restores drug sensitivity and triggers ferroptotic cancer cell death.
https://t.co/XHsQicGKI5

[Oncogene Journal @oncogenejournal]

Could #prostate cancer therapy unintentionally help tumors escape the immune system? Genome-wide CRISPR screen identifies the AR-NF-κB-PRKCD pathway as a key regulator of #macrophage-mediated tumor cell killing. Read more >>>>>
https://t.co/vJQayJULyk

[Oncogene Journal @oncogenejournal]

New research uncovers the NF-κB/ALDH1A1 signaling axis as a key non-genetic #driver of acquired EGFR-TKI resistance in EGFR-mutant NSCLC
https://t.co/H08zCBC3iW

[Oncogene Journal @oncogenejournal]

New findings reveal that kynurenine is more than a metabolic byproduct—it acts as a driver of tumor metabolism, establishing a glycolytic loop that promotes OSCC! >>>>>
https://t.co/CQa9pXlszB