A new mechanistic insight into #EwingSarcoma from a team at @UIchildrens : a previously unrecognized CDK1- and caspase-dependent apoptotic mechanism.
https://t.co/hsLhnuEwcc
🔬@VirginieFirlej & co-workers show that the loss of CDO1 is a marker of aggressiveness in #ProstateCancer and is thought to be responsible for tumour progression in vitro
https://t.co/Wb1OywSBKH
#OpenAccess
Latest study uncovers a neuro-immune mechanism where chronic stress triggers NETs to promote gastric cancer lymph node metastasis. Read more >>>>
https://t.co/U5VWqgKTTZ
New research reveals how bone marrow niche signals—via Galectin‑1 and pre‑BCR signalling—cooperate with oncogenic mutations to shape pre‑leukaemic B cell fate and drive B‑ALL development. #LeukaemiaResearch#BcellBiology#BoneMarrow#CancerBiology
https://t.co/ZPu9vuzn1Z
This study uncovers metabolic-epigenetic pathway by which GPX8⁺ cancer‑associated fibroblasts drive lenvatinib resistance in hepatocellular carcinoma, identifying MCT1 and BRPF1 as promising therapeutic targets to overcome treatment failure. Read more https://t.co/2QEFuIEcix
New research reveals circPARPBP as a key driver of #chemoresistance in triple‑negative breast cancer and shows how the natural compound isoliquiritigenin can help overcome treatment resistance.
https://t.co/RGdybbr19t
New study discovers a circadian mechanism linking NDRG2‑mediated CLOCK stabilisation to suppressed tumour growth and improved oxaliplatin response in colorectal cancer.
https://t.co/0QV4lsU9OI
Microbes aren’t passengers in prostate disease—but their impact depends on timing. This Review reveals when microbial signals matter, and when they don’t.
https://t.co/VFFDO7Lm6m
This study identifies a GBP2–GSDMD–YAP signalling axis that limits immune evasion in #colorectal cancer by suppressing YAP-mediated repression of CXCL9/10/11, thereby enhancing CD8⁺ T‑cell infiltration. Read more :
https://t.co/HFj2wOEREB
New study uncovers how RNA regulatory axis fuels ovarian cancer: the SNRPD2–CPSF7–UBE2K pathway links splicing and polyadenylation to tumour growth—and opens the door to new therapies.
https://t.co/1R8qlMd47e
New study reveals that the ribosomal protein RPS15 plays a key non‑traditional role in promoting prostate cancer progression and metastasis through the DDX21–SCD1 pathway. Read more >>>>
https://t.co/Knj7YKSnVH
A dual role for VPS4 inhibition in inducing tumour cell death and promoting anti-tumour immunity in #rhabdomyosarcoma
https://t.co/SZY4LCxCds
#OpenAccess