PacBio

Our mission is to enable the promise of #genomics to better human health by creating the world’s most advanced #sequencing technologies. #PacBio

[PacBio @PacBio]

SPRQ-Nx chemistry is now shipping worldwide, bringing sub-$300 HiFi genomes to the Revio platform!

This global rollout cuts sequencing costs by 30%, making it easier than ever to scale high-throughput workflows

Learn more: https://t.co/1mLZfkDibV

#PacBio #SPRQNx #Revio

[PacBio @PacBio]

The FDA's new draft guidance on genome editing safety highlights why detecting large indels and chromosomal abnormalities is critical, where short-reads fall short.

HiFi sequencing offers >99.9% accuracy to characterize all editing outcomes.

Learn more: https://t.co/dnAtFYX64s

[PacBio @PacBio]

One of the first preprints using #PacBio Vega is now available.

The study demonstrates accurate detection of mitochondrial heteroplasmy down to 1% using a single full-length mtDNA amplicon and applies the workflow to Parkinson's disease research.

🔗 https://t.co/6q3KT5BPu6

[PacBio @PacBio]

Happening now at #ESHG2026: Nina Gonzaludo is at poster P20.155.E talking about an accelerated HiFi whole genome workflow for comprehensive, rapid long-read sequencing.

She’s here until 13:45. Come stop by, ask questions, and chat with #PacBio!

[PacBio @PacBio]

From packed sessions to a great evening at Kooperativet, Day 2 at #ESHG2026 brought the community together. Check out the recap video! 🎥👇

Hope everyone loved the party! Today is your last day to visit booth 420 and catch our 2 great poster sessions: https://t.co/v8ASbqCkWl

[Deborah Moine @DeborahMoine1]

Presenting our poster P23.040.D at #ESHG2026 today!

We're showcasing how #PureTarget and #PacBio HiFi sequencing enable flexible targeting of challenging genomic regions, from repeat expansions to difficult inherited disease genes.

Looking forward to the discussions! 😃

[PacBio @PacBio]

That is a wrap on our #ESHG2026 Corporate Satellite Symposium!

Thank you to everyone who joined us to learn how long-read population genomics is unlocking clinical impact, reducing testing complexity, and improving patient outcomes today. 🙌

#PacBio

[PacBio @PacBio]

Sharing results from a beta test of PacBio’s SPRQ-Nx reusable SMRT cells using two acquisitions!

This increased SMRT cell throughput reduces sequencing costs for large human WGS projects.

#ESHG2026 #PacBio #ESHG

[PacBio @PacBio]

Next up, Adam Ameur shares that long-read WGS efforts are ongoing in Sweden for population genomics and clinical diagnostics.

They bridge these projects by using a joint analysis framework and shared variant databases.

#ESHG2026 #PacBio #ESHG

[PacBio @PacBio]

The power of long-read sequencing lies not only in finding variants, but in understanding them.

Through phasing, it resolves complex alleles, determines the origin of de novo variants, and detects mosaicism—providing actionable insights that streamline diagnostics.

#ESHG2026

[PacBio @PacBio]

When standard methods fall short, long reads deliver.

Despite exome sequencing analysis, a genetic cause remained hidden. Long-read genome sequencing revealed a mobile element insertion in ADGRV1, solving this previously elusive case.

#ESHG2026 #PacBio

[PacBio @PacBio]

Moving into accuracy: Not every detected variant is a true variant.

Lonneke shares a case where long-read genome sequencing revealed that an apparent LRP5 variant detected by short-read sequencing was actually just a sequencing artefact.

#ESHG2026 #PacBio

[PacBio @PacBio]

Next up, Lonneke Haer Wigmans shares how long-read genome sequencing is becoming a diagnostic reality.

Before implementation, studies in 2023 and 2024 proved this novel technology is robust enough for clinical use and can replace existing testing methods.

#ESHG2026 #PacBio

[PacBio @PacBio]

Big updates are coming for Vega in Q3 2026! Expect higher yield at 90 Gb per day and lower DNA input down to 500 ng.

Plus, you get flexible 2 to 24 hour run times, 5mC, 5hmC, and 6mA methylation calling, and 21 CFR part 11 support for audit tracking and instrument login control.

[PacBio @PacBio]

SPRQ-Nx on Revio is built for true walk-away simplicity.

SMRT Cells stay on the instrument and are entirely software managed. This automatic washing requires zero manual steps, leaving less time managing the instrument and more time on your science.

#ESHG2026 #PacBio #SPRQNx

[PacBio @PacBio]

SPRQ-Nx is shipping now! 🚀

This brings complete genomes at a completely new price with automated multi-use SMRT Cells, upgraded performance up to 48 genomes/week, and richer 5hmC multiomic data.

#ESHG2026 #PacBio #SPRQNx

[PacBio @PacBio]

We are live at our #ESHG2026 Corporate Satellite Symposium! 🧬

Stay tuned as we share updates on how long-read population genomics is unlocking clinical impact today by scaling research and transforming patient outcomes.

#PacBio

[PacBio @PacBio]

Coming up today at 10:30 in Hall C: Don't miss Session C15.1!

#PacBio Scientist Xiao Chen will showcase how HiFi sequencing resolves the complex D4Z4 repeat responsible for facioscapulohumeral muscular dystrophy. See you soon!

#ESHG2026

[PacBio @PacBio]

Day 1 at #ESHG2026 was incredible! Check out our Day 1 recap video to see what went down yesterday. 🎥👇

Onsite today? Don't forget to stop by our Corporate Satellite Symposium at 10:30 in Room A-5: "The power of long-read population genomics to unlock clinical impact."

[PacBio @PacBio]

Our Corporate Satellite Symposium starts in 1 hour at #ESHG2026!

⏰ 10:30-11:30
📍 Room A-5
🔬 The power of long-read population genomics to unlock clinical impact

Join #PacBio to see what's next.

[PacBio @PacBio]

Coming up today at 17:35 in Hall C: Don't miss Session PL3.4! 🧬

Discover how population-scale Kinnex long-read RNA sequencing of the 1000 Genomes Project is uncovering extensive novel isoform diversity. Join us!

#ESHG2026 #PacBio #Kinnex