The Hackenberger Group

We are a Berlin-based #chemicalbiology group thrilled about modifying proteins to advance biological research and drug development.Also known as the Hackenbees!

[FMP Berlin (now on Bluesky) @LeibnizFMP]

P5 technology from Christian Hackenberger group @PhosphorusFive enables a novel ADC now being tested in Phase I/IIa clinical trials.👏 Read more: https://t.co/ALmtOpxipl
#Innovation #CancerTherapy #ADCs #basicresearch

[The Hackenberger Group @PhosphorusFive]

@RubenRagg @ESBOC_Gregynog Very impressive, so you did not forget your running shoes this time 😏😃
Round 2 in Florence at the EPS?

[Chemical Communications @ChemCommun]

New from Oliver Seitz, Christian Hackenberger, first author Alen Koçak and colleagues:

'Fluorogenic cell surface glycan labelling with fluorescence molecular rotor dyes and nucleic acid stains'

@PhosphorusFive @HumboldtUni

https://t.co/LctUOVZOZD

[FMP Berlin (now on Bluesky) @LeibnizFMP]

Inspiring Future Talk with CEO Domink Schumacher @Tubulis_GmbH, joint spin-off #FMP and @LMU_Muenchen. We're proud of our alumnus's achievements and grateful for sharing his journey & insights with us today.
@phosphorusFive #ADC

[Chemical Science @ChemicalScience]

Congrats also to the 3 runners up for the 2023 @ChemicalScience readers' favourite outside front cover!

1st runner up: Marc-André Kasper and Christian Hackenberger et al.! @PhosphorusFive @Tubulis_GmbH

Read about their hydrophilic electrophiles here: https://t.co/sluwM02cOJ

[The Hackenberger Group @PhosphorusFive]

Our post-Xmas party! On stage: the fabulous Judy LaDivina! What a start into 2024! YESSS queen! 🎉🍾 💃👩‍🎤
If you are in Berlin, check out her show „Tell Mama“ @ Bar zum schmutzigen Hobby! 👍👍👍

[The Hackenberger Group @PhosphorusFive]

After 9 years, my term as associate editor for @OrgBiomolChem is now over: it was my pleasure to accept 502 papers in total!
🙏 to all the authors for their trust and patience and the very very many referees I relied on! And of course the awesome team @RoySocChem

[Christian E. Stieger @CEStieger]

Tune in if you want to hear about the latest developments in P(V)-electrophile chemistry from @Tubulis_GmbH and the Hackenberger lab (@PhosphorusFive ). 👨‍🔬👩‍🔬🧪
I'm super excited to share my recent efforts to develop phospho-arginine phosphatase selective probes!

[Chemical Science @ChemicalScience]

We are pleased to welcome Professor Christian Hackenberger (@PhosphorusFive), who will be joining the Editorial Board in January 2024, and handling your organic and chem bio submissions. “When I got the offer, it was a no-brainer. I love ChemSci plus the awesome RSC team." 🤩

[The Hackenberger Group @PhosphorusFive]

Finally #chemistswhorun is back, now at #ISBOC13 in 🇸🇬 Morning treat with @dynafluors @MotonariU and Martin Schnermann. A pity that @conway_group was not here 😞….

[Vince Arafiles @VinceArafiles]

🔥Thanks to our co-authors @JoFraFMP @Luise_Franz @Fitigol and reviewers, the first of many stories is out in @J_A_C_S! 🔥 Read more about the new protein delivery strategy from @PhosphorusFive @LeibnizFMP @AvHStiftung More to come in the near future! https://t.co/8LpYcYnWS9

[The Hackenberger Group @PhosphorusFive]

So so so thrilled, happy and honored to receive this award! 🙏🙏 to my peptide friends in the UK, it means really a lot to me. I was also very fortunate to have several hackenbees with me to help celebrate 🎉🥂 #familyportrait @LeibnizFMP @HumboldtChem @RoySocChem @OrgBiomolChem

[RSC Protein and Peptide Science Group @RSC_PPSG]

Our key note lecture is from Prof Christian Hackenberger @PhosphorusFive who is this years @RSC_PPSG AstraZeneca Prize winner! #PPSG2023

[The Hackenberger Group @PhosphorusFive]

So so happy! Congratulations to the whole team, it’s a pleasure for us to be part of it! And a big shout out to our superstar Sebastian @Sebastianfr1988 at @LeibnizFMP, the constantly running synthesis motor in this endeavor. 😃💪🇨🇴 @HumboldtChem

[Freie Universität @FU_Berlin]

Bundesagentur für Sprunginnovationen @SPRIND fördert internationales Antivirus-Projekt MUCBOOST um @LausterDaniel vom Institut für Pharmazie der #FUBerlin zur Entwicklung eines neuartigen, antiviralen Wirkstoffs mit weiteren 2,5 Millionen Euro ⬇️
https://t.co/RHN5pHbRJR

[The Hackenberger Group @PhosphorusFive]

Thank you to all our collaborators in this study, especially Stephan Hinderlich, @LausterDaniel and the ChemBio platform at @LeibnizFMP 🙏 High throughput screening to manipulate sialic acid production! 😍 #glycotime @HumboldtChem

[ChemBioChem @ChemBioChem]

PhosphorusFive and collaborators identified and functionally characterized small molecule inhibitors in vitro against GNE; a central enzyme in sialic acid biosynthesis (C. P. R. Hackenberger)@PhosphorusFive,@LeibnizFMP,@HumboldtChem@lausterites #openaccess https://t.co/fV7U5EHBUW

[Vince Arafiles @VinceArafiles]

Great to meet a former @PhosphorusFive member in #AusPeptide2023 @AusPeptide See you around @wenyi_li68! Will send your love from Brisbane to Berlin

[The Hackenberger Group @PhosphorusFive]

You cannot attend one of your favorite conferences but your coworker is kicking it? Priceless! Bravo 👏@VinceThePrinzz

[Vince Arafiles @VinceArafiles]

Academic legacy is thriving in Brisbane!🤯🧠 A truly surreal experience presenting our latest work on #ProteinDelivery from @PhosphorusFive @LeibnizFMP right after my PhD mentor @futaki_lab @icr_ku at the #AusPeptide2023 @AusPeptide (photo courtesy of @OlallaLab)

[Vince Arafiles @VinceArafiles]

Academic legacy is thriving in Brisbane!🤯🧠 A truly surreal experience presenting our latest work on #ProteinDelivery from @PhosphorusFive @LeibnizFMP right after my PhD mentor @futaki_lab @icr_ku at the #AusPeptide2023 @AusPeptide (photo courtesy of @OlallaLab)

[ChemEurJ: Chemistry - A European Journal @ChemEurJ]

There's fantastic p-block content to discover, not least a selection of beautiful covers!

Take a look at great chemistry from @LabLichtenberg & @haenisch_group, @FLPchemist, @LabBraunschweig, @ViktoriaGessner, @PhosphorusFive and many more!

Read on: https://t.co/JLGrgMsIme

[Vince Arafiles @VinceArafiles]

Been having a wet and wild summer jn Berlin so we took advantage of the sun 🌞 yesterday to have BBQ 🍖 with @PhosphorusFive! Hopeful that the weather will be better from now 🤞🏽🤞🏽 @LeibnizFMP @campusbuch

[Stephan Hacker (inactive account) @StephanHacker2]

Great talk by Christian Stieger @CEStieger of the @PhosphorusFive lab at #ABPP2023. He talked about his work on phosphorous-based electrophiles for protein conjugation, cysteine profiling and proximity-induced labeling. https://t.co/EPSlMX4umP