RSC Medicinal Chemistry

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[RSC Medicinal Chemistry @rsc_medchem]

We are now on Bluesky!💙

Make sure to follow us for the latest updates from our journal👇

@rscmedchem.rsc.org (https://t.co/XynsZJCn9M)

[Royal Society of Chemistry @RoySocChem]

Social media and connecting with our community – moving on from X.

https://t.co/XzdoBjBvlv

[RSC Medicinal Chemistry @rsc_medchem]

🔓Recent #OpenAccess work by Joshua N. Milstein, @BeharryAndrew & co on nitroreductase-activatable photosensitizers for selective antimicrobial photodynamic therapy is now online, read it here🔥👇

https://t.co/NbxGY6P3MU

📍@UTM & @UofT
👨‍👩‍👧‍👦 @BeharryL

[RSC Medicinal Chemistry @rsc_medchem]

Take a look at this recent Review from Firdoos Ahmad Sofi and colleagues on the recent developments and discovery of dual-targeting inhibitors to bridge the gap in antibiotic drug discovery🔥

https://t.co/PclAvfvQAV

📍@UnivofKashmir

[RSC Medicinal Chemistry @rsc_medchem]

Be sure to read latest research by Oscar O. Castillo Aguilera, Laurence Goossens & co on a multi-step synthesis of a series of non-nucleosidic compounds which mimic the S-adenosyl-L-methionine cofactor and are shown to be DOT1L inhibitors🔥

https://t.co/fztAHhGXOF

📍@univ_lille

[RSC Medicinal Chemistry @rsc_medchem]

🔓Explore this #OpenAccess work by Hannah Maple and colleagues on the development of p300-targeting degraders with enhanced selectivity and onset of degradation👏

https://t.co/G5vArEezDw

📍 @biotechne

[RSC Medicinal Chemistry @rsc_medchem]

Don't miss this Review by Yunfei Du and colleagues covering all FDA-approved drugs containing oxazole and isoxazole nuclei and discussing their pharmacological activities and structure–activity relationships💡

https://t.co/DMgG55WCSj

📍Tianjin University

[Elif OKUTAN @okutanelif]

Our new @rsc_medchem article led by Prof. Esra TANRIVERDİ EÇİK @atauniv1957 on Design, synthesis and in vitro evaluations of new cyclotriphosphazenes as safe drug candidates - now published in RSC Medicinal Chemistry https://t.co/rTqK3lcyu9 @GtuEduTr

[RSC Medicinal Chemistry @rsc_medchem]

We are delighted to announce our #OpenCall for papers for our Sustainable Medicinal Chemistry themed collection📢

Guest Editors: @mlbolognesi, @d_castagnolo and @MagnusJJ_CH_LSF

Find out more about the collection and how to submit, here👇
https://t.co/QKEbP9IWzk

[RSC Medicinal Chemistry @rsc_medchem]

🔓Check out this #OpenAccess Review by Murugesan Sankaranarayanan & co looking at the diverse biological activities and structure–activity relationships of thiochromenes and thiochromanes⬇️

https://t.co/v2FeS61SIh

📍@bitspilaniindia

[RSC Medicinal Chemistry @rsc_medchem]

🔓This month's inside front cover features #OpenAccess work by Xue Zhi Zhao & co on the use of a bivalent “click” approach to develop TDP1-directed PROTACS with potential to enhance the efficacy and selectivity of TOP1 inhibitors, read it here👀

https://t.co/2bfVSTaCGV
📍@theNCI

[RSC Medicinal Chemistry @rsc_medchem]

🔓On the front cover is an #OpenAccess Review article by Constantin Mamat & co on radiohybrid ligands, a new class of radiopharmaceutical which extend the number of matched pairs for radionuclide theranostic applications, take a look👏

https://t.co/Xj6cdl6DHf

📍@HZDR_Dresden

[RSC Medicinal Chemistry @rsc_medchem]

Issue 5 is now online! Read it here👇

https://t.co/iK9I8EleQc

[RSC Medicinal Chemistry @rsc_medchem]

Introducing the RSC Medicinal Chemistry Editor's Choice collection📢

First up is @MariaDuca_CNRS's favourite articles! Be sure to read our blog to see her top choices and why she chose them 👉https://t.co/6CFNxYkb3e

And scan the QR code to see our collection as it grows👀

[Drug Discovery Research Lab KCL @MRahmanLab]

Our new @rsc_medchem paper led by Paolo Andriollo describes a new class of antibody drug conjugate payload that, in a pancreatic cancer model, drives complete tumour regression for 60 days after a single 2 mg/kg dose - outperforming 10 mg/kg Enhertu.

https://t.co/ntJP3NLcAC

[RSC Medicinal Chemistry @rsc_medchem]

Take a look at recent work from Jared J. Anderson and @DanHarki on the identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)🔥⬇

https://t.co/NYZxbCyXES

📍 @UMNews

[RSC Medicinal Chemistry @rsc_medchem]

🔓Be sure to read this #OpenAccess work by Pablo Gastaminza, Javier Adrio, María Ribagorda on the synthesis of a series of chiral indolyl-twistenediones and their antiviral activity, in particular against SARS-CoV-2🔥

https://t.co/3wgYbq3RQQ

📍@UAM_Madrid and @CNB_CSIC

[RSC Medicinal Chemistry @rsc_medchem]

🔓 Don't miss recent #OpenAccess work by Patrick G. Steel & co demonstrating that simple N-linked clemastine fumarate analogues are easy to access and are effective antileishmanials👇

https://t.co/KBX9BavXpe

📍 @durham_uni

[RSC Medicinal Chemistry @rsc_medchem]

🔓Don't miss recent #OpenAccess work by Claire Simons and colleagues on the development of benzofuran-derived sulfamates as dual aromatase-steroid sulfatase inhibitors (DASIs)👏

https://t.co/BNflGuXFWS

📍@cardiffuni

[RSC Medicinal Chemistry @rsc_medchem]

🔓Be sure to read this #OpenAccess work by Subbiah Nagarajan & co on the synthesis of multifunctional glycolipids, using bhilawanol-derived start materials, which show promise as antibiofilm agents and platforms for drug delivery👀⬇

https://t.co/jTfMkwFTPk

📍 @warangal_nit

[RSC Medicinal Chemistry @rsc_medchem]

Explore recent research by Mi Wang, Jiaheng Zhang & co on betaine–salicylic acid cocrystal for enhanced skincare and acne treatment🔥

https://t.co/4zFUgBYTOM

📍 @HIT_China