How can you convince a coronavirus to share its cell entry secrets?
Give it something sweet! 🍬
Using #cryoEM & MD, we show how a sugar-based receptor binds to the HKU1 spike and triggers opening via an allosteric mechanism (🧵).
https://t.co/Jsm61GjTk8
#glycotime#virology
Stoked to share our latest pre-print! Using cryo-EM, we determined the structure of the PfRCR complex, an essential protein complex required for red blood cell invasion by the deadliest form of malaria. 🧵
https://t.co/tzVwmTgfIP
🎉new paper alert @NatureComms 🎉 This one is close to my heart, with my first + highest res #CryoEM structure solved @MIPS_Australia. We can now much better understand how endogenous ligands activate their VPAC #GPCR receptors. (1/2)👇https://t.co/8IvczuBaqi
It was an eventful week, so #Render of the week is featuring a small molecule in a #GPCR binding pocket: work by my friends @RachelJ9908 (her last day at @MIPS_Australia on Friday😢) and @CindyZh46783235 (got a #DECRA)! A tribute to both and their fantastic #cryoEM skills! (1/2)
Pleased to share our latest preprint featuring the #cryoEM structure of mouse Pannexin 1 channel:
Direct Cell Extraction of Membrane Proteins for Structure-Function Analysis
https://t.co/8mo64EHotH
Inviting everyone to the next @arc_gov_au CCeMMP Research Symposium in Melbourne on 1st Sept 2022!
Int keynotes, poster & oral presentations, $ prizes, networking & all things #membrane & #cryoEM🤩
📢All info inc. FREE reg, abstract submission & prizes - https://t.co/AlJdmGrbDp
We are incredibly proud to be ranked number one in the world for Pharmacy and Pharmacology in this year’s QS World University Rankings. Well done to the entire Monash community for incredibly strong rankings this year! #QSWUR@MonashPharm