RenMab

An Innovative Platform of Biocytogen

[RenMab @RenMab]

Our RenMiceHiTS models have been further engineered for challenging or highly homologous targets. The target gene of interest is knocked out, which breaks immune tolerance& results in a more robust immune response👉https://t.co/tt3R9Rs91X
#antibodydiscovery #antibodytherapeutics

[RenMab @RenMab]

Check out @RenMab for your next breakthrough in antibody discovery: Full V(D)J Loci on deck with SUPCE tech, Diverse Human Antibodies for max potential, &Strong Immune Responses just like wild type mice! Learn more at👉https://t.co/a1ipUeiNVR #AntibodyDiscovery #Innovation

[RenMab @RenMab]

Other antibodies targeting Mucins discovered using RenMice are available as below: #RenMice #Innovation #Therapeutics #antibodydiscovery #Antibodies #mucin #renlite

[RenMab @RenMab]

Our fully human common light chain mice, RenLite, are a powerful tool to discover antibodies against 2+ targets for assembly into bispecific or multispecific antibodies. Check out our EGFR x MUC1 BsADC, which was assembled using RenLite-derived antibodies👉https://t.co/BKGboSR1Yt

[RenMab @RenMab]

Our fully human common light chain mice, RenLite, are a powerful tool to discover antibodies against 2+ targets for assembly into bispecific or multispecific antibodies. Check out our EGFR x MUC1 BsADC, which was assembled using RenLite-derived antibodies👉https://t.co/BKGboSR1Yt

[RenMab @RenMab]

Tissues from these mice are screened using industry-leading screening technologies in our facility, shortening the time from immunization to hits and sequenced clones to a few short months👉https://t.co/NJ2U4pFS12 #antibodydiscovery #antibodytherapeutics #beacon #singlecell

[RenMab @RenMab]

W/ the most comprehensive coverage of the human VDJ loci available, @RenMab mice can generate robust immune responses w/ a diverse antibody repertoire for screening following immunization.

[RenMab @RenMab]

W/ the most comprehensive coverage of the human VDJ loci available, @RenMab mice can generate robust immune responses w/ a diverse antibody repertoire for screening following immunization.

[RenMab @RenMab]

Interested in discovering antibodies to challenging or highly homologous targets such as GPCRs? We offer a library of models in which the target gene of interest is knocked out, which results in a more robust immune response for your antibody discovery👉
https://t.co/Mt3RdEX7ue

[RenMab @RenMab]

Without a need for downstream antibody humanization, the versatility of our platforms is unmatched. Learn more about our RenMab models: https://t.co/V1ybXXVc0O (Image created with BioRender) #antibodydiscovery #antibodytherapeutics #beacon #singlecell #antibodycloning #innovation

[RenMab @RenMab]

Fully human antibodies/nanobodies derived from our fully RenMice® models can be further developed into multiple therapeutic modalities, including antibody-drug conjugates, cell engagers, CAR-T, CAR-NK, bispecifics, and multispecifics.

[RenMab @RenMab]

Fully human antibodies/nanobodies derived from our fully RenMice® models can be further developed into multiple therapeutic modalities, including antibody-drug conjugates, cell engagers, CAR-T, CAR-NK, bispecifics, and multispecifics.

[RenMab @RenMab]

Stay tuned for our Antibody-based Assets posters session in the 38th Annual Conference of Society for Immunotherapy of Cancer (SITC)! Meet our team at booth 223 to learn about our recent advances in antibody drug discovery👉https://t.co/iVvgq8zq5S #SITC #immunotherapy #bispecific

[RenMab @RenMab]

3.Peptide Boost: Enhances the CD4+ T cell response. 4.High-throughput Screening: Beacon tech for comprehensive screening. Learn more about our Anti-GPCR Antibody Technology Platform here: https://t.co/9ElYXL0tzK #AntibodyDiscovery #GPCR #Innovation #Oncology

[RenMab @RenMab]

Maximize GPCR antibody discovery with our Anti-GPCR Antibody Technology Platform! Our strategies for success: 1. Target KO: Harness our RenMice HiTS Platform to generate species-cross-reactive antibodies. 2.DNA Immunization: Native expression for epitope access.

[RenMab @RenMab]

Maximize GPCR antibody discovery with our Anti-GPCR Antibody Technology Platform! Our strategies for success: 1. Target KO: Harness our RenMice HiTS Platform to generate species-cross-reactive antibodies. 2.DNA Immunization: Native expression for epitope access.

[RenMab @RenMab]

Check out our posters below:
Poster #10: Potent efficacy in mice and favorable safety in cynomolgus monkeys of DM001, a novel TROP2xEGFR bispecific ADC
Poster #11: DM002, a novel HER3xMUC-1C bispecific ADC, exhibits potent anti-tumor activity in preclinical models
#WorldADC

[Biocytogen @biocytogen]

Stop by booth #23 to speak with our team members if you are also attending World ADC San Diego conference from Oct 17–18! Be sure to check out our posters highlighting DM001, a novel TROP2xEGFR bispecific ADC & DM002, a novel HER3xMUC-1C bispecific ADC👉https://t.co/kUVZdtpTOo

[RenMab @RenMab]

🚀 Dive into the future of antibody discovery with RenMice! 🧬Catch the on-demand webinar &uncover the power of RenLiteⓇ & RenNano models for bispecific/multispecific antibodies. Real case studies show how we're revolutionizing your projects. Watch now: https://t.co/JwHlR5e0iC

[RenMab @RenMab]

Immunization of our target KO fully human antibody RenMice yields antibodies that target both non-homologous also conserved regions. This approach increases the likelihood of identifying antibodies that specifically target conserved homologous regions👉https://t.co/h34xc6pz3m

[RenMab @RenMab]

Discover cutting-edge science with our HLA/@RenMab mice & high-throughput antibody screening! We're revolutionizing human antibody generation targeting MAPs, outperforming TCRs in affinity & specificity. Explore our TCR-Mimic Antibody Platform👉 https://t.co/7dzu5cJOqQ #tcrmimic

[RenMab @RenMab]

Explore our cutting-edge BsADC platform: Leveraging the high-throughput RenLite® technology, we enable the discovery of bispecific ADCs targeting 200+TAA targets, ensuring remarkable tumor specificity, potent anti-tumor activity & efficient CMC processes👉https://t.co/jK92ZJP7DV

[RenMab @RenMab]

Our RenMice HiTS models are designed to discover antibodies against the toughest targets, such as GPCRs! W/ these models, we've knocked out the target gene, eliminating immune tolerance and supercharging the immune response.  Dive into our poster for more: https://t.co/Mt3RdEX7ue

[RenMab @RenMab]

Check out @RenMab for your next breakthrough in antibody discovery: Full V(D)J Loci on deck with SUPCE tech, Diverse Human Antibodies for max potential, &Strong Immune Responses just like wild type mice!
Learn more at👉https://t.co/a1ipUeiNVR
#AntibodyDiscovery #Innovation

[RenMab @RenMab]

Learn more: https://t.co/V1ybXXVc0O

#antibodydiscovery #antibodytherapeutics #beacon #singlecell #antibodycloning #innovation #preclinicalresearch #immunotherapy #biotech #biotechnology #biopharma #cancerresearch #cancertherapy

[RenMab @RenMab]

Discovery of antibodies in RenMice completely eliminates the need for artificial humanization. Offering the most comprehensive coverage of the human VDJ loci available, RenMice generate robust immune responses w/ a diverse antibody repertoire for screening following immunization.

[RenMab @RenMab]

Discovery of antibodies in RenMice completely eliminates the need for artificial humanization. Offering the most comprehensive coverage of the human VDJ loci available, RenMice generate robust immune responses w/ a diverse antibody repertoire for screening following immunization.

[RenMab @RenMab]

Although antibodies generated in wild-type animals can be artificially humanized for further clinical development, these extra engineering steps are often costly and time-consuming, and may compromise affinity to the desired antigen.
#antibodydiscovery #antibodytherapeutics