RethinkX

Independent research organization forecasting speed & scale of technology driven disruption I Co-founded by @tonyseba & @jamiearbib I

[RethinkX @rethink_x]

1 billion people will have access to optimal health before 2040. How? Health Optimizer Therapies. RethinkX's new report #RethinkingHealth is here. Are you ready for the 10x shift? #RethinkingHealth #RethinkX #GLP-1s #HealthOptimizerTherapies https://t.co/D1GRW808y6

[RethinkX @rethink_x]

UK biotech firm @sunbearbio has completed the first run of its yeast-derived cocoa butter alternative in a setup that costs less than 10% of the industry standard. https://t.co/a1ZyUrg9hI

[RethinkX @rethink_x]

Article highlights RethinkX and Tony Seba's groundbreaking cost-curve analysis that proves "solar, wind and battery are the dominant energy system." https://t.co/l12gsV9uwu

[RethinkX @rethink_x]

How the inevitable Humanoid Robotics disruption rewrites economics 👇 #FutureOfWork #SystemDynamics #Macroeconomics #HumanoidRobotics #RethinkX #DisruptionTheory

[RethinkX @rethink_x]

Today's robots are the most expensive and least capable they will ever be. From here, they only get better... and cheaper. How can we protect people over profit? #RethinkX #FutureOfWork #HumanoidRobots #TechDisruption

[RethinkX @rethink_x]

Are our economic models ready for the speed of the humanoid robotics disruption?
👇 #RethinkX #HumanoidRobotics #FutureOfWork #LaborDisruption

[Adam Dorr @adam_dorr]

A fun conversation with @danmiller999 about solving climate change with technology!
https://t.co/Shx3HTqnJw

[RethinkX @rethink_x]

Are you prepared for the post-scarcity economy? #Robotics #AI #Automation #FutureOfWork #RethinkX #Disruption

[RethinkX @rethink_x]

Across the arc of human history, addiction treatment has largely been a story of limitation, stigma, and modest results. Until now... https://t.co/8kuDOYRe6x

[RethinkX @rethink_x]

GLP-1s aren’t just making people eat less… they’re changing what we eat entirely. If cravings for junk food and dessert vanish, what happens to the junk food industry? #GLP1 #Ozempic #Zepbound #FoodIndustry #HealthTrends #BehaviorChange

[RethinkX @rethink_x]

https://t.co/wHVOsa2X9j

[RethinkX @rethink_x]

Did you know that pet food accounts for roughly 1/4 - 1/3 of total U.S meat consumption?! In 2019, RethinkX predicted that Pet Food would be a perfect entry point for Precision Fermentation (PF). Guess what? The FDA just cleared PF lamb protein for dog food. The timeline for the disruption of industrial agriculture has just accelerated. 📉⌛ 🥩🐕

🥩 #PrecisionFermentation #FoodDisruption #Rethink

[RethinkX @rethink_x]

Are we looking at Ozempic all wrong? 💊Right now, GLP-1s are treated as a last resort for obesity and diabetes. But we’re entering a new era where most adults will use them on low, maintenance doses—not to cure illness, but to maximize daily wellness. "Optimizing well" is about to become just as vital as "eating well." Ready for the health optimization era? #GLP1 #HealthTech #Ozempic #Longevity #FutureOfMedicine

[RethinkX @rethink_x]

Everything in the economy is downstream of just two things: Energy and Labor. When Solar + AI make both of them superabundant, we will see a "prosperity explosion" the likes of which humanity has never seen...We're just a few years away from a stellar future. Are you ready? ⚡

[Adam Dorr @adam_dorr]

Articles like this misunderstand the future of medicine in a fundamental way.

On the USS Enterprise, would Dr McCoy wait until Captain Kirk got ill or frail before treating him? Or would he receive a slate of low-dose maintenance therapies that optimized his health all the time?

The idea that “dependency” is a bad thing is absurd. We don't call daily vitamin and mineral intake a bad thing. We call it healthy diet.

Health Optimizer Therapies are the future of medicine. GLP-1s like Ozempic are just the very beginning.

[Adam Dorr @adam_dorr]

There is still widespread misunderstanding of what GLP-1s like #Ozempic and the new #retatrutide actually represent. They aren't just treatments for disease, like antibiotics. They are Health Optimizer Therapies (HOTs).

One key mistake lies in the efficacy unit of analysis. Media coverage and even respectable scientific experts are comparing semaglutide (Ozempic/Wegovy) and tirzepatide (Zepbound/Mounjaro) with next-gen drugs like retatrutide using the wrong metric: % weight loss per unit time.

This is not all that meaningful, because you can lose as much weight as you want as fast as you want on any of these drugs - it's entirely a matter of dosage. You can lose 5lbs or 50lbs just as fast on Ozempic as on retatrutide. You just have to take a big enough dose.

Heck, you could lose more weight even faster if you took cisplatin (used in cancer chemotherapy). Cisplatin causes extreme nausea.

Why not take cisplatin instead of retatrutide? Why not take Ozempic instead of retatrutide?

The adverse side effects.

You get more bang for your buck with retatrutide. A better benefit:detriment ratio.

But the real magic of retatrutide isn't just in treating obesity. The REAL magic is that when used in low-dose for health optimization, there are ZERO *perceived* adverse effects. (There may be real harms below the level of perception, that remains to be seen and caution is of course warranted).

Folks like @cremieuxrecueil already track anecdotal reports from large numbers of retatrutide users (below). What the chart doesn't show is that at maintenance doses, users who are already "healthy" trim down closer to their ideal beach bod, and just feel fantastic all around. (Independent health benefits beyond just weight loss may also be a factor here). People report feeling a decade younger on reta. ALL upside, NO downside (perceived).

This is why retatrutide has taken the Silicon Valley tech sector by storm.

It's not just about weight loss. It's about health optimization, and retatrutide is the first HOT that genuinely feels like 21st Century medicine - stark benefits, near-zero downside, pure magic.

And retatrutide is just the beginning.

[RethinkX @rethink_x]

What if a single technology could wipe out $2.3 Trillion in healthcare costs while simultaneously disrupting the $800B+ alcohol and tobacco industries? https://t.co/pkMrrLfixp #HOTs #RethinkX #SebaFramework

[Adam Dorr @adam_dorr]

They said @tonyseba was crazy when he published Solar Trillions in 2010

[RethinkX @rethink_x]

https://t.co/qtMH48XQiu

[RethinkX @rethink_x]

Read our 15 key AI/Robotics disruption insights https://t.co/QweAcG2zAl

[RethinkX @rethink_x]

"We're at the beginning of the future." - Dr. Adam Dorr of RethinkX speaks to the disruption of labor by AI and Humanoid Robotics.