Rosa

Pathologist in Toledo University Hospital Complex

[Michigan Pathology @UMichPath]

🔬This week’s theme: Placental #Pathology

➡️Day 2: What’s your #DailyDx of these placental finding?

➡️What clinical scenario(s) might you expect to see this?

➡️What gross findings might you see in the placenta in association with this finding?

#PlacentalPath #UMichPath

[Andres Surgical Path @Andresangel3]

Dividing membrane shows a Diamniotic Dichorionic Twin Placenta (Di-Di Placenta). Two chorions plastered together. It makes the likelihood of dizygous twinning (fraternal) much more probable than monozigous (identical).

[Charlie Herndon @DrCycloPath]

A, B, & C are evidence of maternal vascular malperfusion
Evidence of fetal vascular malperfusion include thombi & stem vessel obliteration (large vessels) as well as avascular villi & villous stromal-vascular karyorrhexis (distal vessels)
#PlacentaPath #Placenta #PediPath #PathTwitter #PathResidents
📽️🙏Dr. Drucilla Roberts https://t.co/pHIH9JrLvu
✅D

[Charlie Herndon @DrCycloPath]

Which of the following is evidence of fetal vascular malperfusion?
A) Decidual arteriopathy
B) Distal villous hypoplasia
C) Hypertensive infarct
D) Villous stromal-vascular karyorrhexis
#PlacentaPath #Placenta #PediPath #PathTwitter #PathResidents

[Dr. Arkadip MD @pathognosis22]

Soft tissue tumor pattern based approach #BST #NEETSS #NEET #pathology #pathognosis #histopath #histopathology #soft_tissue

[ɴᴀᴠᴇᴇɴ ᴋᴜᴍᴀʀ @DrNovinoTailor]

Q - 603. Mallory bodies are seen in:
#MedX #MCQs

[Janira Navarro @Janiranavarro]

Thyroid
RAS-like: The follicular family
BRAF-like: The papillary family

Dr. Jung #USCAP2026 #pathology #PathX #PathTwitter

[Dr. Arkadip MD @pathognosis22]

Breast trucut. What's your opinion? #breastpath

[Janira Navarro @Janiranavarro]

Triple Negative Breast Cancer Subtypes
WHO 6th edition

Dr. Allison
#USCAP2026 #PathX #PathTwitter

[Michigan Pathology @UMichPath]

🔬 This week’s theme: Gynecologic #Pathology

➡️ Day 1: What’s your #DailyDx of this ovary? Similar findings were present in both ovaries.

➡️ What could be associated with this finding?

➡️ We’ll tweet the answers & some quick facts tomorrow!

#GYNPath

[Janira Navarro @Janiranavarro]

67 yo male
History of supraglottic/glottic SCC s/p radiation
Now presenting with glottic stenosis

Biopsy shows sialometaplasia: a benign reactive process that is frequently misdiagnosed as recurrent SCC

- Commonly occurs after radiation or chemoradiation for head and neck SCC
- Can appear on ANY mucosal site
- Preserves lobular architecture
- Smooth borders with minimal atypia
- Myoepithelial layer sometimes present (pic 4)

Dr. Cipriani #USCAP2026 #pathology #PathX #PathTwitter

[Jerad Gardner, MD @JMGardnerMD]

Growing list of SMARCB1 (INI-1) & SMARCA4 deficient sarcomas & other tumors. -Khin Thway #USCAP2020 #pathology #BSTpath

[Pathology mcqs @Pathology_mcqs]

🎯 Answer: Uterine Leiomyosarcoma
Diagnosed using WHO 2022 histopathologic criteria —
🔹 Cytologic atypia
🔹 Tumor cell necrosis
🔹 Mitotic threshold (HPF / mm²)

📌 Different subtypes = different diagnostic rules

#AnswerReveal #UterineLeiomyosarcoma #Leiomyosarcoma #WHO2022

[Pathology mcqs @Pathology_mcqs]

Molecular Pathology of Ependymoma — simplified & exam-ready 🧠✨
From ZFTA & YAP fusions to Posterior Fossa A/B and spinal MYCN tumors, molecular classification now drives prognosis, grading, and reporting.

#Ependymoma #Neuropathology #MolecularPathology #WHO2021 #PathologyMCQs

[Pathology mcqs @Pathology_mcqs]

🔬 Chromophobe RCC vs Oncocytoma

Raisinoid nuclei + perinuclear halo + diffuse CK7 → Chromophobe RCC
Round nuclei + granular cytoplasm + CK7 negative/focal → Oncocytoma
📌 Nuclear detail makes the diagnosis.

#RenalPathology #ChromophobeRCC #Oncocytoma #GUPathology #CK7

[Manual Of Medicine @ManualOMedicine]

Musculoskeletal Tumours

#medtwitter #foamed #usmle

[Eman Magdy @EmanMagdy91D]

Diagnostic IHC Algorithm for Sinonasal Small Round Blue Cell Tumors

From Kurt's notes

#pathology

[Charlie Herndon @DrCycloPath]

❌ Perniosis
-Superficial and deep perivascular lymphocytic infiltrate
-Aggregates around eccrine glands (peri-eccrine)
-Marked papillary dermal edema

[Raza Hoda, MD @RazaHoda]

What translocation is found in this tumor? 🧬🔬

Poll in comments below 👇

Answer revealed on Monday 🔮

#PathX #PathTwitter #breastpath #molpath

[Fatima Shamsuddin @FatimaShamsPath]

🎯 Clear cell hidradenoma

👉 64-year-old male with right arm soft tissue swelling

🔬Histology highlights:-
•Well-circumscribed dermal tumor
•Solid and cystic architecture
•Lobules of epithelial cells in hyalinized stroma
•Prominent clear cells with glycogen-rich cytoplasm
•Evidence of ductal differentiation

PanCK and EMA positivity shows epithelial and highlights ductal differentiation 

🔎 Key differentials:-
•Metastatic renal cell carcinoma
•Poroma / poroid hidradenoma
•Hidradenocarcinoma
•Clear cell squamous cell carcinoma

💎 How to distinguish
•Lack of infiltrative growth, necrosis, and significant atypia
•Presence of ductal structures and biphasic cell population
•Clinicopathologic correlation is essential

⚓️ Prognosis
•Benign tumor
•Excellent prognosis after complete excision
•Local recurrence possible if incompletely excised

#PathTwitter #Dermatopathology #SkinAdnexalTumor
#Hidradenoma #PathologyCase