Rosetta@Home

Running our screensaver helps advance research on cancer, COVID-19, HIV & more | Follow @UWproteindesign to learn more about the science | Not for profit 💻 🧬

[Rosetta@Home @RosettaAtHome]

The COVID-19 projects on our platform are headed into human clinical trials! Our amazing online volunteers have played a role in the development of a promising new vaccine as well as candidate antiviral treatments.

From the whole team at @UWproteindesign, THANK YOU! (1/2)

[Foldit @Foldit]

Our biggest change EVER! On Sept 7, we're launching new A.I. tools and a feature-packed website.

• Level up your profile
• Easily share your solutions
• Enjoy up to 200x faster gameplay thanks to machine learning

After 14 years, Foldit is still FREE and not-for-profit!

[Institute for Protein Design @UWproteindesign]

protein design

[Institute for Protein Design @UWproteindesign]

Today our admin team met with @RepJayapal to celebrate new Federal investments in 10 key projects across the Seattle area. Our request will enable the purchase of advanced laboratory equipment that will help us discover new cures for current and future pandemics.

[Institute for Protein Design @UWproteindesign]

Today we report new #deeplearning approaches for functional #proteindesign. We use these to generate immunogens, receptor traps, metalloproteins, enzymes, and binder proteins. We validate the designs using in silico and lab tests.

https://t.co/Aa1xlHwHyg

[Institute for Protein Design @UWproteindesign]

The COVID19 vaccine developed by @KingLabIPD & @VeeslerLab has met its Phase 3 trial goals and is now under review for full authorization in Korea.

SK bioscience, the company leading clinical development abroad, found the vaccine outperformed Oxford/AstraZeneca’s in the clinic.

[Rosetta@Home @RosettaAtHome]

@sahajsarup Hey Sahaj! The job queue is on and off depending on lab demand. When there are Rosetta jobs in the queue like forward folding, they should also get sent to willing arm64 clients. Thanks.

[Institute for Protein Design @UWproteindesign]

"Baker and his colleagues tested their strategy on 12 target proteins. [T]he researchers wound up with miniproteins that bound as strongly as, if not stronger than, most antibodies do."

https://t.co/fdUoFid4lF

[Institute for Protein Design @UWproteindesign]

IPD director David Baker, together w John Jumper and @DemisHassabis of DeepMind, will receive the 2022 Wiley Prize in Biomedical Sciences for pioneering work on protein structure prediction. Their award lectures will be streamed April 1. Learn more at: https://t.co/mBVGBVh0ic

[EBRC @EngBioRC]

New in the feed! EBRC In Translation's @Andrew_C_Hunt and Kevin Reed interview Dr. David Baker, professor at @UW and director of @UWproteindesign, about the practical and philosophical of #proteindesign and using video games for #science. Check it out at https://t.co/28t6OFcGln

[Rosetta@Home @RosettaAtHome]

@TheBoinc @RosettaCommons @UWproteindesign We'll look into this. Thanks for flagging!

[Institute for Protein Design @UWproteindesign]

Applications are open for our Undergraduate Summer Research Fellowships! Fellows will receive stipends as they attend seminars & conduct cutting-edge research in one of our affiliate labs in Seattle.

Program Dates: Jun 21 – Aug 19, 2022

Learn more: https://t.co/N2QCTPX2Tg

[Nature Reviews Drug Discovery @NatRevDrugDisc]

Interested in structure-based drug design? ICYMI, this news article in the October issue discusses the implications for drug discovery of the recent major advances in protein structure prediction from AlphaFold and RoseTTAFold https://t.co/rseQDgpmb5

[Institute for Protein Design @UWproteindesign]

In this new video, the team at @SciShow explains how A.I. is transforming protein science.

"The future of biology is starting to take shape." — @hankgreen

WATCH: https://t.co/OHtkPbA9O7
#RoseTTAFold #AlphaFold #AlphaFold2

[Institute for Protein Design @UWproteindesign]

S. Korea has just approved a Phase 3 trial of the COVID nanoparticle vaccine we reported last year in Cell: https://t.co/3hhOtOLXpK All Phase 1/2 trial participants induced neutralizing antibodies. @KingLabIPD @veeslerlab @UWMedicine

https://t.co/H7TG9MzobN

[Foldit @Foldit]

Did you know that you (yes you) can now use the world's most advanced AI software to improve your gameplay inside Foldit?

Alphafold is in Foldit❗️

Learn more in this month's Lab Report: https://t.co/DchsHA213E

[Meagan Phelan @MeaganPhelan]

Just out in @ScienceMagazine: @UWproteindesign-led researchers present RoseTTAFold – a neural network approach for protein modeling with accuracies near those of what DeepMind’s AlphaFold2 has achieved. The tool’s code is freely available. https://t.co/Qz3CTK5qkC

[Eric Topol @EricTopol]

A big day for 3D protein structure prediction via #AI deep learning. Down to atomic accuracy w/ open-source code, methodology @nature @ScienceMagazine
@DeepMind @UWproteindesign @demishassabis @UWBiochemistry
https://t.co/jRZfG47WvQ
https://t.co/5oHKzrvTnh

[Foldit @Foldit]

In this month's Lab Report video, we share some unexpected results from the lab.

+ New protein structure
+ Puzzle updates
+ Design of the Month

WATCH:
https://t.co/28DDn88S6E

[Timo Kissel @timokissel]

You too can help advance medicine and science by running Rosetta@Home to use spare computing capacity of your computer