Ruaridh T Miller

Stir uni sports science student and above average runner

[Ruaridh T Miller @ruaridh_t]

Phosphorylation levels don't equal enzyme activity levels, therefore kinase activity was measured directly to give a more definite result https://t.co/AuYbXE01qe #R7EM17

[Ruaridh T Miller @ruaridh_t]

Biopsy taken from upper leg region vastus lateralis, however due to the protocol involving running surely a more activated muscle from the calf region would of have been more appropriate? https://t.co/xm7JR5VNSg #R7EM17

[Ruaridh T Miller @ruaridh_t]

A clear quantitative methodology established to measure PKB & p70S6K1 activity with the use of one muscle biopsy, no conclusion necessary but a very in depth summary is provided https://t.co/AuYbXE01qe #R7EM17

[Ruaridh T Miller @ruaridh_t]

Suppression of p70S6K reduces MPS after high fat feeding post exercise. Acknowledgment that CHO restriction is less severe than previous studies. Impact on results? https://t.co/enHx1C2d4l #R7EM17

[Ruaridh T Miller @ruaridh_t]

EAA ingested through drink bought from Holland and Barrett, without testing how can we be sure of its actual EAA content? https://t.co/U5EWEUlsXD #R7EM17

[Ruaridh T Miller @ruaridh_t]

MRI an extremely reliable way to measure muscle cross sectional area however it's a costly method making study design difficult to replicate https://t.co/Gb6si3PBf4 #R7EM17

[Ruaridh T Miller @ruaridh_t]

+ve trend seen on arm muscle structure & function with the supp of EAA after period of immobilization, perhaps the use of a cast may have been more beneficial than a sling? in order to ensure immobilization https://t.co/Oq4fX0onb2 #R7EM17

[Ruaridh T Miller @ruaridh_t]

Immobilisation of the leg leads to a lower MPS response to AA supplementation in recreationaly active participants. Novel and clever idea of using signed tape to ensure the brace wasn't adjusted during immobilization period https://t.co/yTShhZYVJU #R7EM17

[Ruaridh T Miller @ruaridh_t]

Non-technical summary is a very good addition as it furthers the target audience and allows for better understanding https://t.co/NZT4LiuBZx #R7EM17

[Ruaridh T Miller @ruaridh_t]

They refer to Net myofibrillar FSR which is a made up concept, it doesn't exist. A mistake the reviewer should of picked up on? https://t.co/SSsySur8cF #R7EM17

[Ruaridh T Miller @ruaridh_t]

Eccentric res ex causes greater anabolic signalling compared to concentric res ex. Lack of control over diet and physical activity could have impacted results https://t.co/cOlCcLK1fX #R7EM17

[Ruaridh T Miller @ruaridh_t]

Consumption of Pro+Cho stimulates myofibrillar MPS but not mitochondrial after prolonged cycling. Participants asked to avoid training 48hrs prior to testing however training doesn't cover all forms of PA https://t.co/gIBvFoTz8L #R7EM17

[Ruaridh T Miller @ruaridh_t]

Data taken from the results of 6 previous studies, however the limitations of this are clearly outlined and addressed in the conclusion https://t.co/ogpflJEXu6 #R7EM17

[Ruaridh T Miller @ruaridh_t]

Physical activity not controlled day before testing so assumed participants were rested, ex can influence MPS up to 24hrs after ex https://t.co/it4Pp7PU4P #R7EM17

[Ruaridh T Miller @ruaridh_t]

Younger men require less pro ingestion to stimulate MPS compared to older men. A wider age range for older men maybe required due to potential variability? https://t.co/Q9L78SkCCg #R7EM17

[Ruaridh T Miller @ruaridh_t]

Increased pro ingestion above amount suggested to maximise MPS results in higher whole body net pro balance due to decr in pro breakdown. Funding received from program designed to increase demand for beef, influence on results?https://t.co/dZdmu94MfC #R7EM17

[Ruaridh T Miller @ruaridh_t]

Use of smartphone app for recording diet very questionable, surely a controlled diet would of been a more reliable method https://t.co/JEcK4wRhIW #R7EM17

[Ruaridh T Miller @ruaridh_t]

Extremely tricky to blind this study therefore participants would of known when on high pro and this may of influenced time trial performance https://t.co/u21fDswa1W #R7EM17

[Ruaridh T Miller @ruaridh_t]

High pro intake is possibly beneficial to endurance performance, lack of statistical significance may have been due to small sample size https://t.co/MCg3X6a20W #R7EM17

[Ruaridh T Miller @ruaridh_t]

Pro intake of 5.5 times the recommended allowance has no effect on body comp in res train. High dropout rate possibly due to -ve side affects of high pro diet not mentioned?https://t.co/Cdh6hnfhrs #R7EM17