Bruce Stillman

Biochemist. President of Cold Spring Harbor Laboratory @CSHL

[Bruce Stillman @StillmanBruce]

A new review just out with John Diffley and Janet Iwasa provides high resolution videos of the earliest stages of DNA replication in eukaryotes, the formation of pre-Replicative Complexes. Comparison of mechanisms in yeast and human cells is presented. See https://t.co/lRZand81D4

[Bruce Stillman @StillmanBruce]

New DNA sequencing method

[Elliot Hershberg @ElliotHershberg]

Extremely clever new NGS tech from Roche 🧬

If it's hard to discriminate between nucleic acids accurately with a nanopore, why not synthesize a new polymer off a DNA template that is easier to sequence?

It's an intuitively simple idea, but took *a ton* of creative nucleic acid chemistry + enzyme engineering to design modified NTPs and create polymers of them.

It's been very interesting to see Roche move into the NGS market, and time will tell how this stacks up with the growing set of totally orthogonal approaches people are cooking up for sequencing tech.

It feels like we are entering another renaissance for biological measurement infrastructure—which is super important.

“Progress depends on the interplay of techniques, discoveries, and ideas, probably in that order." - Sydney Brenner

(These animations of sequencing tech will never get old to me. What a time to be a biologist!)

[Bruce Stillman @StillmanBruce]

Interesting cancer meeting @CSHL Banbury Center

[Neri Oxman @NeriOxman]

Here is the O° one-minute version.

[Neri Oxman @NeriOxman]

Meet O° – a collection of shoes and textiles whose creation and reincarnation starts and ends with biology.

100% biodegradable. 0% petrochemicals. 0% microplastics. 0% forever chemicals. No assemblies. No glues.

Here’s to a future where products can grow from—and reincarnate into—plant matter.

OXMAN is initiating discussions with potential partners, investors, and brand collaborators to bring the production of O° shoes and textiles to scale and to market. We look forward to hearing from you.

Press release here
https://t.co/PbLiYYHLic

Learn more here
https://t.co/dm4Xa4douk

Contact us here
https://t.co/FSIuYvqGFg

[Bruce Stillman @StillmanBruce]

@AlbanyMed @URochester_SMD @CSHL @Stanford Another very well deserved award

[World Laureates Forum @wlaforum]

The relentless pursuit of life science🧬and medical breakthroughs💊by scientists has long been a cornerstone of public health protection. At the 2024 #WLA Life Science Forum co-chaired by the 2019 Canada Gairdner International Award Laureate Bruce Stillman (@StillmanBruce) and Chen Zhu from the Chinese Academy of Sciences, global experts will gather to discuss cutting-edge research and innovation in these fields. Join us to listen to their invaluable insights at https://t.co/tgygU18DwQ! #WLAForum @GairdnerAwards @CSHL

[Bruce Stillman @StillmanBruce]

@GurdonInstitute Congratulations Tony on a well deserved recognition. Onward fundamental discovery science.

[Bruce Stillman @StillmanBruce]

@FondationLOreal @CNRS @institut_curie Congratulations to Geneviève for this well deserved recognition

[Bruce Stillman @StillmanBruce]

@DiffleyLab But the water must be freezing 🥶

[ASBMB @ASBMB]

Congratulations to Bruce Stillman of @CSHL on winning the ASBMB's Stadtman Award. Join us in Hemisfair Ballroom C2-3 for his award lecture, happening now! #DiscoverBMB

[Thomas Miller @TCR_Miller]

I am happy to announce that we've recently posted our new manuscript, titled: ‘Cell Cycle Regulation has Shaped Budding Yeast Replication Origin Structure and Function’ on BioRxiv (https://t.co/E9siBoXi36). We hope you enjoy! Tweetorial below:

[Tim Green @tfgg2]

In conclusion, we hope this demonstrates the potential for atomically-accurate structure prediction for the full range of important biomolecules and their interactions using AlphaFold-like methods!

https://t.co/Rsa3qY0bdb

6/7

[Bruce Stillman @StillmanBruce]

@DiffleyLab Agreed

[Bruce Stillman @StillmanBruce]

Important new click chemistry, particularly for biological based compounds

[Chemistry World @ChemistryWorld]

Iterating on sulfur fluoride exchange, K. Barry Sharpless and @HarborSpring have introduced phosphorus fluoride exchange for building complex products from a central phosphorus hub. ‘Just one step to the left and the world is different,’ says Sharpless.
https://t.co/j4kVuh6wOd

[Cold Spring Harbor Laboratory @CSHL]

Please take a moment to read CSHL President and CEO @StillmanBruce’s essay on the crucial need to invest not only in the bold visions of our current scientists but also those of future scientists who will lead the way into new frontiers. https://t.co/T8U3jJrkls

[Miguel @MiguelSDM]

Some weeks ago I started my post-doc era in this amazing lab (the house behind me) with Dr. Lippman at @CSHL
Very excited to see how it goes and keep learning about plant genomics! 😁🧬🍅🌱
Sorry for my face, it’s very sunny today!

[Cold Spring Harbor Laboratory @CSHL]

Congratulations to Associate Professor Jessica @tollkuhn on being chosen to receive one of @PershingSqFdn’s MIND Prizes. Her project highlights the pioneering aspect of her research on how sex hormones affect the body throughout our lifetimes.

https://t.co/iO294Ru4tW

[Bruce Stillman @StillmanBruce]

Remarkable that an elected representative can not understand simple logic

[The Problem With Jon Stewart @TheProblem]

State Sen. Nathan Dahm (R-OK) has penned several bills loosening gun restrictions, including the nation’s first anti-red flag law. He thinks these bills protect the Second Amendment – and that they make us safer. We think it's probably one or the other. Watch it on @AppleTVPlus.

[Semir Beyaz @beyazlab]

Two terrible earthquakes hit southeastern part of Turkey, in particular my hometown Samandag and Hatay had a lot of damage with currently minimal rescue and support, leaving many friends and relatives under collapsed buildings and others outside in cold weather and fear.