Evidence

[Evidence @XposedEvidence]

@CallofDuty Contender:

[Modern Dad @ModernxDad]

He just shared a beautiful message for the world‼️

[Healthy Mind / Life @H_MindH_Life]

Read this 3x

[Men of Purpose @Men_Of_Purpose]

Are you happy...

[Leaders 𝕏 Junction @LeadersJunction]

This is how manifestation works‼️

[Crypto Rover @cryptorover]

THIS IS NOT A COINCIDENCE:

In 2018, $BTC tapped the 200D SMA after exactly 220 days.

In 2026, Bitcoin tapped the 200D SMA after exactly 220 days.

$82,500 was the local top?

[Leaders 𝕏 Junction @LeadersJunction]

Once you understand this nothing feels impossible.

[Daisy @level_x_up]

Watch your thoughts

[Craft Gallery @5min__crafts]

Fished for years, finally learned why hooks always twisted

[Massimo @Rainmaker1973]

Simple Tai Chi hand exercises for relaxation

[Massimo @Rainmaker1973]

New research from the University of Helsinki reveals a significant connection between severe infections and increased long-term risk of dementia. Analyzing nationwide health registry data from over 375,000 Finnish adults, the study found that hospital-treated infections — including severe urinary tract infections (such as cystitis) and dental caries — were robustly associated with higher dementia incidence years later.

For individuals under age 65, certain serious bacterial infections and pneumonia roughly doubled the risk of early-onset dementia. The associations held strong even after researchers adjusted for 27 other chronic conditions, including heart disease, stroke, and mental health disorders. On average, these infections were diagnosed about five to six years before dementia was identified.

Scientists suggest that the systemic inflammation caused by severe infections may damage the blood-brain barrier, affect cerebral blood vessels, and accelerate brain changes that contribute to cognitive decline. These findings indicate that what are often viewed as temporary or localized health issues may have lasting effects on brain health.

The researchers emphasize that better prevention and prompt treatment of common infections could represent an important and underutilized approach to reducing dementia risk in the population.

[Sipilä PN, Korhonen K, Lindbohm JV, Kivimäki M, Martikainen P. The role of noninfectious comorbidities in the association between severe infections and risk of dementia in Finland: A nationwide registry study. PLOS Medicine. 2026;23(3):e1004688. doi:10.1371/journal.pmed.1004688]

[Massimo @Rainmaker1973]

Your wisdom teeth could save your life.

They contain stem cells that could repair your heart, bone, and even brain tissue.

What was once considered medical waste may soon be a powerful tool in regenerative medicine.

Scientists have discovered that wisdom teeth — often removed and discarded in adolescence or young adulthood — contain a rich supply of mesenchymal stem cells capable of transforming into bone, muscle, nerve, and other vital tissues.

Dental stem cells have shown promise in preclinical studies for conditions ranging from arthritis and diabetes to cognitive disorders like Alzheimer’s and Parkinson’s disease.

And unlike stem cell collection from bone marrow or blood, harvesting dental pulp during wisdom tooth removal involves no additional procedures or discomfort.

[Journal of Natural Science, Biology and Medicine. "Current overview on dental stem cells applications in regenerative dentistry." Stem Save (2025). Current Clinical Applications for Stem Cells]

[Evidence @XposedEvidence]

@grok @SuperGeniusEth @cjzafir @GnusAi Okay and what’s your take on this if you’d take a deep dive @grok

[Massimo @Rainmaker1973]

A new shot literally regrows knee cartilage.

Researchers at Stanford Medicine have identified a novel strategy to regenerate articular cartilage in knees and potentially prevent or treat osteoarthritis (OA).

The method targets 15-hydroxyprostaglandin dehydrogenase (15-PGDH), an age-related enzyme—or "gerozyme"—that accumulates in aging tissues and drives degeneration.

In aged mice, small-molecule inhibitors of 15-PGDH, delivered systemically or via intra-articular injection, promoted cartilage thickening and regeneration of functional hyaline articular cartilage.

This occurred without recruiting stem or progenitor cells; instead, existing chondrocytes underwent transcriptional reprogramming to a youthful state, with reduced populations of inflammatory and hypertrophic/degradative cells and expanded matrix-producing articular chondrocytes.

The inhibitors also reversed natural age-related cartilage thinning, improved joint function, and—when administered after simulated ACL injuries—strongly mitigated post-traumatic OA progression and associated pain.

Human OA cartilage explants from total knee replacements responded similarly in vitro, showing decreased degradation markers and evidence of new articular cartilage formation.

Given that an oral 15-PGDH inhibitor has already completed Phase 1 safety trials for age-related muscle atrophy, the findings open a path toward disease-modifying, regenerative therapies that could delay or obviate the need for joint replacement surgery.

[Agarwal, P., Su, S., Ancel, S., et al. (2025). Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration. Science. DOI: 10.1126/science.adx6649]

[Evidence @XposedEvidence]

@GnusAi @grok so what do you think?