Hey friends, I’m Geraldine Ezeka #BlackInCancerRollCall. I’m a 5th year PhD candidate @UMmedschool
identifying different molecular targets of sulforaphane, a nature derived anti-cancer agent, in mesothelioma.
hey STEMverse: during your PhD (or research experience), did you find that 1 of the limitations to your progress was 1) inadequate reagents (ex antibodies that sucked) 2) inadequate equipment (ex equipment didn’t do as suggested) or 3) improper protocol 4) or a mix of the above?
The $SRPT rollercoaster is not over. FDA recommended removal of voluntary hold on Elevidys for ambulatory patients and the $SRPT stock shot up ~50% after close, consistent with that trend, it’s up 40% at open.
$ABVX going from $10 to $69 after reporting positive Phase 3 data that no one believed in is insane. We were obvs bullish and anticipated a >100% increase upon positive data
Yesterday GHRS stocks were up 85%. Excited to continue watching the story develop as we anticipate an update on the clinical hold, an end of Phase 2 meeting with the FDA, and their Ph3 design.
Yesterday was a great day in neuropsychiatric drug development with GH Research reporting positive results from the Ph 2 trial evaluating their inhalation formulation of DMT for treatment resistant depression
Current standard of care JnJ’s SPRAVATO displayed a 4 point reduction in MADRS score while GH001 achieved a placebo adjusted 15 point reduction in MADRS
Let’s chat about Reviva Pharma
Reviva Pharma is a clinical stage pharmaceutical company developing a serotonin/dopamine modulators in a host of indications with the lead being schizophrenia
Hi #MedTwitter 👋🏾
My name is Amday Wolde! I’m an M4 at @OhioStateMed applying to #Psychiatry for #Match2025
I’m passionate about URiM mentorship (https://t.co/67gP2xON2Y) & addressing SDOH!
Academic interests are cultural & lifestyle psychiatry!
My hobbies include ⚽️🏀👨🏾🍳
Cassava stocks plummet 85%…again, not a surprise considering the inconclusive Phase 2 results which begs the question, why did the FDA let them run a Phase 3?
A disheartening day for Alzheimer’s disease drug developers with disappointing results coming from both Cassava Sciences and Alector/Abbvie Phase 3 and Phase 2 clinical trials, respectively.
Albeit the Cassava results were expected considering little impact seen in Phase 2
@EthanInvests Oh I completely agree, interested in $MRNA for that exact reason, especially with positive recent data in solid tumors. COVID helped fund the cancer initiatives for sure
@EthanInvests Also curious about how vaccine companies (like $MRNA) will take a hit after Trump appoints different folks in office that may not support vaccines
@EthanInvests Hard to predict since market is heavily dependent on success of clinical trials. A bit easier to follow the data for small/midcap therapeutics companies but more difficult to predict for more service based companies like Ginkgo.