Endif

Biotech investor: MYOV, TGTX, PHAT. Tech: ENVX, SOFI, PLTR

[Mario Nawfal @MarioNawfal]

🇪🇸 UNBELIEVABLE SCENES out of CEUTA!

Spain’s Civil Guard chief just admitted the border has completely collapsed.

Thousands of military-aged African men flooded across in a matter of hours, immediately after the government offered amnesty to illegals.

Amnesty is a magnet. The message goes out, and the flood begins.

Every country that does this ends up in the same place.

Writer: Oliver

[zipjet @zipjet]

$TGTX recent question by an RRMS patient that needs to move on from Tysabri and the responses of others that have moved to the anti-CD20's.

The Question
A patient diagnosed with Relapsing Remitting Multiple Sclerosis (RRMS) five years ago, previously stable on Tysabri, must switch medications due to a recent flare and a new lesion. Given the choices of Kesimpta, Ocrevus, or Briumvi, the patient has narrowed the options down to Ocrevus or Briumvi and is seeking personal experiences—particularly regarding Briumvi's efficacy and tolerability compared to Ocrevus, given that Briumvi is a newer treatment.

Essence of User Responses
Respondent 1: Switched from Ocrevus to Briumvi 2.5 years ago. Noted fewer infusion reactions and significantly shorter post-infusion fatigue (recovering by the next morning on Briumvi, compared to two days of exhaustion on Ocrevus).

Respondent 2: Strongly recommends Briumvi, noting that patients are actively switching from Ocrevus to Briumvi specifically to experience fewer side effects.

Respondent 3: Switched from Kesimpta to Briumvi three years ago (starting right at launch). Reports excellent results, a high quality of life, and the ability to maintain an active lifestyle (cycling and working out).

Respondent 4: Had a positive history with both Tysabri and Ocrevus, followed by an unsuccessful stint on Rituxan due to poor tolerability. Scheduled to switch to Briumvi in the fall because it is generally expected to be easier to tolerate, though notes individual responses vary.

Respondent 5: Was stable on Ocrevus since 2019 but switched due to lab work anomalies. Experienced more side effects and post-infusion issues with Briumvi than with Ocrevus, and intends to re-evaluate with their neurologist if the next infusion causes issues.

Respondent 6: Switched from Tysabri to Briumvi, passing over Ocrevus because Briumvi is reported to have slightly better efficacy. Describes it as the best decision ever, noting increased energy and reduced brain fog compared to their time on Tysabri.

Respondent 7: A peer in a similar clinical situation (facing a medication change after four stable years) expressing shared uncertainty.

The Case for Switching to Briumvi (from Ocrevus and Kesimpta)
Based on the shared patient experiences, the clinical and lifestyle arguments for choosing Briumvi over Ocrevus or Kesimpta center on three main areas:

1. Superior Post-Infusion Tolerability and Reduced Side Effects
Multiple patients who transitioned from Ocrevus highlighted a significant drop in systemic side effects. A primary advantage is the reduction of the post-infusion "washout" or exhaustion period. Patients noted that while Ocrevus caused multi-day fatigue, Briumvi allowed them to return to baseline energy levels by the following morning.

2. Quality of Life and Energy Gains
Patients moving from both Tysabri and Kesimpta to Briumvi reported tangible improvements in daily functioning. Specific benefits mentioned include:

Marked reductions in brain fog.

Increased daily energy levels.

The ability to easily sustain demanding physical activities, such as cycling and regular workouts.

3. Perception of Enhanced Efficacy
Among patients making the decision between the newer glycoengineered anti-CD20 monoclonal antibody (Briumvi) and the older standard (Ocrevus), there is a strong consensus that Briumvi offers a slight edge in targeted efficacy, making it a compelling next step for individuals experiencing breakthrough disease activity on prior therapies.

[Emmanuele @Biotech2050]

Make no mistake. Roche stating “upper end of our previous assumption” means/ translates to: $TGTX market penetration is hitting our worst case scenario and will significantly impact our $8B annual revenues.

$TGTX trades at a market cap of x1 Roche’s annual revenues!

[Dr. Maalouf ‏ @realMaalouf]

Did you know?

Muslims don’t take over and block streets to pray in Qatar, Dubai or even Saudi Arabia, the birthplace of Islam. It’s illegal and considered disruptive.

They only do it in the West to assert dominance.

[dough @semodough]

$TGTX Cowen ⬆️PT $75 updated $TGTX model -increased Briumvi revenue estimates for 2028+ to account for anticipated launch
of a SC Briumvi formulation, resulting in new peak revenue estimate of $5.3B in 2035 (vs.
the prior $3.5B). also increase DCF-based PT to $75 (vs. the prior $50) maintain
our Buy rating.

[NWRain-Judi @RYboating]

They don't care that your taxes were stolen!

That's because the left is in on all the fraud. 😉

Vote for America 1st candidates only! 🇺🇸

[Women's Voices Australia @womensvoicesau]

Not sure I could love Germaine Greer any more than I do. Everytime I watch this clip 💜💜 her a little more. For all the sex denialists this is the original critique of “gender”. Take note: Women are a sex class.

[Endif @_Endif]

@RosannaInvests @AshtarCodes @grok I'm not short, I'm long and considering buying more. What you highlighted is not synonymous with your statement "cutting reliance on third-party launch".

[Endif @_Endif]

@AshtarCodes @RosannaInvests @grok They aren't. She misrepresented what they said.

[Chloe Cole ⭐️ @ChloeCole]

The Chloe Cole Act has PASSED COMMITTEE! We are one step closer ensuring children in ALL of the United States are protected from transgender medical experimentation!

Thank you @JudiciaryGOP for standing up for future generations!

[Libs of TikTok @libsoftiktok]

Massachusetts Governor Maura Healey boasted about BLOCKING gas pipelines in her state and then complained that they can’t get gas…

[Jason Miyares @JasonMiyaresVA]

Reminder: the year Fidel Castro took power, Cuba had the same GDP as Greece. The year he died, Cuba had the same GDP as Sudan. In other words: Socialism. Fails. Every. Time.

[Sovey @SoveyX]

Listen to North Korean defector Yeonmi Park explain how her grandparents were promised much of what Mamdani and the Democratic Socialists of America are promising today:
- Free healthcare
- Free housing
- Free education
- A government that will take care of everyone

In return, they surrendered their freedom.

Tyranny rarely arrives looking cruel. It arrives smiling, speaking softly and promising compassion.

Liberals, I beg of you, don’t listen to conservatives if you don’t want to.

Listen to the North Korean defector.

It will not be different this time.

This is how it begins.

[zipjet @zipjet]

[News] $TGTX Maintained by HC Wainwright & Co. -- Price Target Raised to $77 (GuruFocus) - Jul 13, 2026

[Justine Bateman @JustineBateman]

These people are ridiculous.
They have lost all tethers to a sense of self. Their entire identity now relies on this treasonous hate of America. They make up fantasies of how horrible America never was to justify their need to "fight tyranny." They have no identity but this. And they cling to it with a death grip, because they have nothing else.
None of it is true. Not the fantasy about America about which she is shrieking, not her identity of believing herself to be some "hero" in a movie about an oppressive government, and not the resulting congress-free, senate-free, President-free, childish (and completely chaotic) future she sees for this country.
She is an infant.
She and others like her will not get their way. Not even close. If you have a modicum of common sense, it's time to let your line in the sand about tolerance be made known.
Myself, I have a limit to tolerance.
I have a limit to patience.
I know there is a limit to free speech.
If your plan is to tear down the United States of America, if your plan is treason, I will not tolerate you, I will have zero patience for you, and I will not defend your right to free speech.
@FBI @FBIDirectorKash

[Eric Daugherty @EricLDaugh]

🚨 LMFAO! Leftists just posted this video of a park in NYC to try and say communism is working under Zohran Mamdani...

...but Bryant Park is PRIVATELY funded capitalist with private security

You can't make this up 🤡

Communists are CLOWNS.

https://t.co/B6dKCFw6Ty

[John McAfee 🇺🇸 News @mcafeenew]

🚨ZOHRAN MAMDANI THE COMMUNIST GRIFTER MAYOR CUNT “TAXED THE RICH” TO PAY FOR ROBERT DE NIRO’S MANSION… THEN TURNED AROUND AND SPENT $15 MILLION IN TAXPAYER MONEY ON TAYLOR SWIFT AND TRAVIS KELCE’S WEDDING SECURITY — WHILE HIS COUSIN’S MOVING COMPANY GOT THE CONTRACT TO HAUL THEIR SHIT IN AND OUT!

Follow @RedLivesMatterQ

This is how communism actually works.

Zohran Mamdani loves screaming “tax the rich” while he’s in office. He went after Robert De Niro’s wealth tax and acted like he was some hero for the working class.

But when Taylor Swift and Travis Kelce decided to get married at Madison Square Garden, this fraud suddenly found $15 million of New Yorkers’ money for “security and support.”

Sources at the venue say Swift and Kelce used Mamdani’s cousin Ezekiel’s local moving company to get all their equipment in and out.

So the taxpayers got fucked twice:
1. $15 million for celebrity wedding security
2. Mamdani’s family got a nice fat contract on top of it

All while this communist piece of shit pretends he’s fighting for the little guy.

New Yorkers are getting robbed blind by this fraud and his family. He taxes the rich, then turns around and hands millions to his own relatives and celebrity friends.

That’s not socialism. That’s just plain old corruption with a red flag.

Zohran Mamdani is a grifter. Plain and simple.

Share this everywhere so every New Yorker sees exactly how their mayor is robbing them!

Follow @mcafeenew for more drops.

[Kirralie Smith @KirralieS]

I have been ordered to pay $95,000 in "damages" to two men in women's sport because I apparently hurt their feelings. It is potentially going to be doubled because I didn't pay in 30 days. So that is $190,000 in total to reward two men in women's sport. I am appealing in the NSW Supreme Court, so for now, there is a stay on the orders.

@salltweets has been ordered to pay a man $20,000 for not allowing him on her female only app. His hurt feelings claim is hoping to be challenged in the High Court. Sall is still waiting to see if leave will be granted for the appeal.

Jasmine Sussex could have to pay up to $95,000 to a man with hurt feelings who falsely claimed he could breastfeed a tiny baby. Her case is still to be heard by a Queensland tribunal.

None of these numbers include the court costs which run into millions.

Others have lost jobs, been censored, gaslit or threatened if they speak the truth or object to the lie that men can be women.

Men who wish they were women not only want to dominate our sports, spaces and services, they are also trying to make money as they go. It appears quite lucrative if they succeed.

Stand with us. Men are not women and we should never be penalized for stating the facts - especially in court where evidence and facts are meant to be paramount.

[Isaac @isaacrrr7]

ÚLTIMA HORA - Después de que se revelara que se abrieron 50 mezquitas en Dallas Fort Worth en los últimos 24 meses, una mujer descubrió que el mayor donante del gobernador de Texas, Greg Abbott, es un musulmán paquistaní que le ha dado más de 14 millones de dólares, incluidos 2 millones de dólares solo este año.

[Bill Ackman @BillAckman]

.@NYCMayor Mamdani’s appointed advisory commission is recommending an 18.2% raise for himself and other elected officials purportedly because of inflation, yet his self-appointed Rent Guidelines Board — which is supposed to consider inflation in setting rents— froze rents for two years.

A question for the mayor:

How is this fair or appropriate?