Congrats to @nicoleleejw (and other @ConfinementLab co-authors) on her main story coming out this month in @CellReports! Check out this thread if you’re interested in what Nicole discovered on the role #MechanicalMemory plays in facilitating cell migration in #confinement
Troponin I (slow skeletal) is our #CellLineOfTheWeek! ❤️🔬
Our human stem cell lines & plasmids are openly available to reduce the barriers to scientific discovery. 🧫🚀
📦 Distributed by @Coriell_Science & @Addgene#OpenScience
Check out this editorial in Circulation Research by Dr. Marie-Louise Bang about our paper on alpha-actinin-4 in the cardiac Z-disc. It both summarizes our findings really well (image gives a taste of it; there is more) and lays out future directions.
https://t.co/LhXyzCcVVi
Our final #preprint list of 2025 is now up on FocalPlane!
In this post, we focus on recent (and recently updated) preprints in bioimage analysis. Let us know if you have any recommendations of preprints that we have missed.
https://t.co/l1p9yLJh3H
Human monocytes placed on a soft matrix undergo phase separation into micro domains. On glass/plastic, monocytes do not form such domains.
See more details in our recent paper in Nature Materials: https://t.co/1AYrcqtmZj
Analyzing organelles is HARD. They're complex, but critical to understanding biology. Current tools are manual, organelle-specific, or can't handle large 3D datasets.
With an easy install and a click of a button, Nellie solves ALL these problems!
https://t.co/4C5ItjAP7I
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A hungry heart muscle cell (cardiac myocyte) videoed through a microscope by Burnette Lab graduate student, @EmmaKoory. What is it eating and why? We may never know....... #CellBiology
Been doing a lot of time lapses of iPSC-derived cardiac muscle cells lately! Here's one of my favorites. This cell is expressing fluorescent alpha-actinin-2 and the colors represent depth. Movie length = 24h with frames taken every 20m. #microscopymonday#cellbiology@MAG2ART
"Non-Muscle α-Actinin-4 Couples Sarcomere Function to Cardiac Remodeling" is now online at Circulation Research! Congratulations to Dr. James Hayes on this ambitious work! There is a lot in the paper so let's start with the graphical abstract. @CircRes
https://t.co/OQ4tj9RGnu
Research|Giardini et al. present an imaging method that combines measurements of electrophysiology with high-resolution 3D structural reconstructions and detects electrical coupling between cardiomyocytes and non-myocytes in hearts.
https://t.co/zg2NWb7MG4
https://t.co/RpIr2GIWg8