Today, we announced that the US FDA has granted zovegalisib Breakthrough Therapy Designation for PIK3CA-mutant, HR+/HER2- advanced #breastcancer, supported by data from our ReDiscover trial testing zovegalisib at the 600mg BID fasted & 400mg BID fed doses in combo w/ fulvestrant.
"We won the national championship at Indiana University, it can be done."
Indiana Football head coach Curt Cignetti with @MollyAMcGrath after beating Miami 👏
We will present our preclinical work in #vascularmalformations at #VAC2025 today. As we advance our commitment to innovation, we’re preparing to initiate the Phase 1 clinical trial of RLY-2608 in PI3Kα-driven vascular malformations by the end of Q1. Congratulations Fabien & team!
Would recommend to anyone looking at grad school opportunities around the interface of engineering and biology. Not sure everyone can say this about their PhD program, but I truly enjoyed my time @MITdeptofBE!
We are accepting applications to join our 2025 PhD cohort at @MITdeptofBE! Learn more about the program, application process, and opportunities for application assistance below. Please share with junior scientists interested in the interface of #biology and #engineering! 🧫🧬🧑🔬
Today, we announced positive interim data for RLY-2608 demonstrating clinically meaningful progression free survival for RLY-2608 in patients with HR+/HER2- #BreastCancer. President of R&D Dr. Don Bergstrom shares more about the significance of these data below. Tune into our conference call this morning, September 9, at 8:00AM ET for details. $RLAY
https://t.co/az3i15DMKJ
Biden is going to deserve a ton of credit if Dems actually win. Seems like an obvious choice from the outside, but not many people at the pinnacle of power actually choose to step out of the way.
My fellow Democrats, I have decided not to accept the nomination and to focus all my energies on my duties as President for the remainder of my term. My very first decision as the party nominee in 2020 was to pick Kamala Harris as my Vice President. And it’s been the best decision I’ve made. Today I want to offer my full support and endorsement for Kamala to be the nominee of our party this year. Democrats — it’s time to come together and beat Trump. Let’s do this.
🧵 (1/9) Today, beginning at 8AM, we will be live tweeting from our New Program & Platform Event. Check back here for real-time details on our new program disclosures and other exciting updates. See this morning’s press release and register for our live webcast here. https://t.co/eGAbB03vvW $RLAY
Today, we announced a clinical trial collaboration to develop RLY-2608 with atirmociclib, Pfizer’s next-generation selective CDK4 inhibitor currently in Phase 1 studies, in triplet combination in patients with PI3Kα-mutated, HR+, HER2-metastatic #breastcancer. Clinical start by YE 2024. Find full details here. https://t.co/xawTM13Wlj $RLAY
Our review on the latest and greatest CRISPR technologies for genome, epigenome and transcriptome editing is now online @NatRevMCB! We cover recent CRISPR engineering strategies and clinical applications https://t.co/6XADcCKIXh