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An open access publisher focused on innovation in healthcare and health policy through high quality, peer reviewed, open access research.

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This study evaluated #triptorelin treatment for #prostatecancer (2010-2021) in 3,411 Italian patients (mean age 76.8). Patients received triptorelin alone (38.9%) or with anti-androgens (61.1%); 24.8% died, 30.4% switched treatments. |https://t.co/zEB17JH82E

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This study evaluated the #cytotoxicity, #selectivity, and #clonogenicity of Saudi medicinal plants on liver cancer (HepG2). Opuntia ficus-indica showed potent effects, with selective action on #cancer cells. GC-MS revealed key phytoconstituents. | https://t.co/9wqUeFuNgJ

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🔬 September Highlight! 🔬
This was the most viewed article on #GRHTA in September! Check it out here https://t.co/u2tTdeWATj

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This study evaluated persistence and adherence to b/tsDMARDs for #psoriaticarthritis in Italy. #Biosimilars showed similar or better outcomes than originators, supporting their use to improve efficiency in #healthcare management. | https://t.co/PzTk9y1jcO

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This study assessed the reliability of goniometric finger ROM in 20 healthy adults. Intra-rater reliability was moderate to good (88.7%), but inter-rater reliability was lower (69.0%), possibly affected by physical differences among raters. | https://t.co/fahMmYOOBZ

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#Levofloxacin at therapeutic doses induces #oxidativestress, reduces antioxidant enzyme activity, and triggers eryptosis (cell shrinkage, PS externalization) and hemolysis in #erythrocytes, suggesting cautious use and further research. | https://t.co/Bu6WKt0pOd

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Epic Sciences' CTC-based ERBB2 (#HER2) assay detects HER2 amplification in metastatic #breastcancer with 85% sensitivity and 94% specificity. It offers 69% sensitivity for unstable CTCs, aiding patients when tissue biopsy isn't feasible. | https://t.co/bUrIh32BEq

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For over 13 years, the Italian Journal of Physiotherapy has championed evidence-based practice, evolving into the Archives of Physiotherapy. Now partnered with AboutScience, it embraces #openaccess, enhancing its impact on #physiotherapy research. | https://t.co/8VAT9QEZ4B

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This study examines using #AI, like #ChatGPT, in regulatory processes for CE marking #medicaldevices under EU Regulation 2017/745. It highlights prompt engineering's role and stresses the need for training to optimize AI effectiveness | https://t.co/OAe2bAZYQT

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This study examined a #Toxoplasmagondii-derived peptide's #anticancer potential on Caco-2, Hep-G2, and HT29 cells. The peptide reduced cell viability and apoptosis-related gene expression, showing promise as an anticancer agent.| https://t.co/wUD7Zumxwn

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A survey of 165 physical therapists showed that while they see adapted physical activity (APA) and adaptive sports as beneficial for patients with #neurologicalconditions, promotion is infrequent due to barriers, except among specialists. | https://t.co/MPwuLUEaJi

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The “#DexcomONE Experience” study found high satisfaction among insulin-treated patients in Italy, with 93% finding the CGM device useful for #diabetes management and 90% reporting a positive impact on their quality of life. | https://t.co/AGlirt65JL

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This study found elevated #IL-21 levels in patients with chronic #periodontitis and #gingivitis compared to healthy individuals, suggesting IL-21 as a potential #biomarker for periodontal disease. Further research is recommended. | https://t.co/hiv40NWC3F

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#Treatmentfidelity (TF) in #clinicaltrials ensures interventions are delivered as designed. It includes adherence to protocol, quality of delivery, and participant compliance. TF is essential for trial integrity alongside bias and evidence certainty | https://t.co/SFBm1O3hsJ

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The study assessed French physiotherapists' self-perceived competency as first-contact practitioners for #lowbackpain. FCPs felt skilled in diagnosis and referrals but less so in drug prescriptions and sick leave issuance. More training is needed. | https://t.co/wD5Tebkh5K

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Pregnancy in #CKD patients is complex, with risks of miscarriage and complications. Effective management requires therapy adjustments, close monitoring, and careful nutrition to ensure maternal and fetal health.| https://t.co/xEj0ruUjMd

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The study evaluates the impact of roxadustat for CKD-related #anemia in Italy, showing reduced costs for iron supplementation and pharmaceuticals. Savings are maintained if #roxadustat's discount exceeds 60.3%, proving cost-effectiveness. | https://t.co/M4PG0XGU2Q

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This study found that the polyherbal formulation #Enteropan® reduces #Pseudomonasaeruginosa virulence by impacting biofilm formation, protein synthesis, and quorum sensing. It influenced 17% of the bacterial genome, revealing potential #drugtargets
| https://t.co/7SbMHL35KW

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This study analyzed 21 patients #post-shouldersurgery, finding that over 120° shoulder flexion requires 83° of GH flexion and abduction. External rotation ROM must be at least 53% of the opposite side for effective overhead mobility. | https://t.co/2EoMCuR5hb

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🌟 Meet the Editor: Prof. Roger Chammas 🌟

Introducing Prof. Roger Chammas, our Associate Editor for #Oncology.

🔗 Find out more here: https://t.co/Hbnh8kXCu1

#Oncology #CancerResearch #TranslationalResearch #PrecisionOncology #MeetTheEditor