Framingham Heart Study + NHLBI PI; research on Platelets in CVD; bleeding; using population approaches: genetics, epidemiology, RNA biology, bioinformatics
Now online in Blood, the largest genetic study to date of Heavy Menstrual Bleeding, reveals 36 Risk Loci. Most loci are not related to coagulation/hemostasis and instead other biological processes: https://t.co/NLZuH4bKOM
There is a postdoc opening in March 2025 in my NIH Lab. Position can be located in either Boston/Framingham or D.C. area (Bethesda/NIH). Info an applying is here: https://t.co/8nGmdYz0WH
@JennyGenetics Large new genetic study on fibrinogen with 18 new loci, including new FGG/FGB/FGA region signals, now online at Blood. https://t.co/Kckr7yfBTy
Following our discovery in humans for a role of GRK5 in platelets (https://t.co/l6GTeCLfU9), glad to report platelet-specific knockout of Grk5 also modifies thrombin activation and thrombosis: https://t.co/xFUoaW0Pnk
Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity - PubMed (https://t.co/adXLGIEpuL) now online. Exercise regimens might be a dose to reduce thrombotic platelets. #ISTH2024
Our new article on factors influencing Platelet assays (e.g., blood draw time, time to test, age, sex, medications, technician, seasonality) and inter-assay correlation in >3,400 people is now online: https://t.co/dzDZLSQBJL @RPTHjournal@isth
Our new article in Platelets suggests associations between blood vessel diameter variation, subclinical vessel calcification and platelet function https://t.co/vXnc8O17Zi
ISTH Reach-the-World Fellowships offer emerging clinicians and researchers a global study opportunity. Read about the latest recipients here and plan to submit your application later this year: https://t.co/AuiAUabqrg
There is a postdoc position currently available in my group focused on bioinformatics/platelet genomics. NIH payscale with no prior postdoc experience is around $65-80K/year depending on specific expertise. Please contact me for more details.
Our new study out on Alcohol+Platelet reactivity in 3,427 people. Alcohol associated with lower Platelet reactivity; generally stronger effects in women. Aspirin intake >>> Alcohol. No support for a Red wine-reduced Platelet reactivity hypothesis here: https://t.co/yMlBBBx90j
For an up-to-date view and review on platelet RNA-seq studies, check "Sources of variability in the human platelet transcriptome" recently in press https://t.co/mYb25XgvfS @Florian_Th
The ISTH GenOMICS SSC is expanding its mission and focus to include not only Genetics but multi-OMICS topics (Transcriptomics, Proteomics, etc.) We are seeking Co-Chairs in all OMICS domains. Please apply by July 31 @ ISTH SSC website #ISTH2023