Andrew Fratoni

Pharmacist. Associate Director, Clinical and Laboratory Studies at CAIRD, Hartford Hospital. Thoughts are my own. He/him #UConn #FinsUp #PinstripePride

[Andrew Fratoni @AFratty]

@AeschlimannJeff I’m glad to see you haven’t lost your touch! 😂

[Andrew Fratoni @AFratty]

🆕publication from our group❗️ Excellent work from Dr. Abouelhassan during her post-doc fellowship with us at Hartford! This important work supported by the FDA and led by my colleague Dr. Abdelraouf.

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️⚡️⚡️#JAC from Dr.Nicolau Hartford group
Ampicillin-sulbactam against Acinetobacter baumannii infections: pharmacokinetic/pharmacodynamic appraisal of current susceptibility breakpoints and dosing recommendations #IDXposts https://t.co/r6UkbFbkTE

[Andrew Fratoni @AFratty]

While developed to target KPCs - many of our clinically used BL/BLIs have further utility! Many thanks to the reviewers whose comments and suggestions really helped strengthen this review. 🙌🏼

[Clinical Infectious Diseases @CIDJournal]

Non-KPC Attributes of Newer β-lactam/β-lactamase Inhibitors, Part 1: Enterobacterales and Pseudomonas aeruginosa

https://t.co/fWR6J3AcNy

[Tomefa Asempa @PK_asempa_PD]

Omadacycline powder for research procured from unauthorized commercial vendors may be impure and/or unstable | Antimicrobial Agents and Chemotherapy

🫡So glad to see such work being done to ensure quality and reproducible studies are being conducted.
https://t.co/ITDha6LqaY

[Andrew Fratoni @AFratty]

@MadelineBelk Consider checking out the breakpoints episode on bactrim dosing (episode 83). I spend some time on the PKPD data our lab has generated towards the end of the episode. The references should be in the episode notes.

[Andrew Fratoni @AFratty]

Are we overcalling resistance of beta-lactams in MBL producing isolates because of supra-physiologic zinc levels in the testing media? Really thought provoking findings from my lab colleagues Drs. Abdelraouf and Nicolau!

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

In vitro-in vivo discordance in β-lactams activities against MBL producing Enterobacterales has been described
🔥Deciphering the Efficacy of β-Lactams in the Face of MBL Derived Resistance in Enterobacterales
Supraphysiologic Zinc in Broth is the Culprit🔥 https://t.co/BM3YVbgQGz

[Andrew Fratoni @AFratty]

Members of our CAIRD team @hartfordhosp are headed to Barcelona tomorrow for ECCMID (@ESCMID)! Stop by our posters and presentation on Sunday and say hello 👋

[Jon Rothstein @JonRothstein]

There have been 25 NCAA Tournaments since 1999.

UConn has won six of them.

College Basketball goes through Storrs.

[UConn Huskies @UConnHuskies]

THE UCONN HUSKIES ARE GOING TO BOTH FINAL FOURS‼️

@UConnMBB 🤝 @UConnWBB

[Andrew Fratoni @AFratty]

Great opportunity still open for PGY2 ID at Hartford Hospital in Phase 2! Consider joining our clinical ID colleagues with elective rotation offered in our lab at the Center for Anti-Infective Research and Development. 🧫 🧪 🥼

[Tyler Ackley, PharmD @Ackley_PharmD]

@Floralquinolone Not sure if here is the best place to tag on but, Hartford Hospital is going into Phase II for our ID PGY-2 program. If anyone is interested in hearing more about the program, feel free to send me a DM as a previous-resident turned preceptor!!

[Andrew Fratoni @AFratty]

Looking forward to giving this presentation on this “hot topic” in ID! Mark your 🗓️ and hope you can join for the discussion. 🤓

[SIDP @SIDPharm]

Beta-lactam TDM on your mind? Register today for this live CE webinar to learn more about optimizing TDM for this class of antibiotics! Visit https://t.co/5cqvoHBLI5 to learn more.

[Andrew Fratoni @AFratty]

Oops that link is the wrong paper, but I guess consider giving that one a read too 😅

Correct 🔗:
https://t.co/6MejYBeup1

[Andrew Fratoni @AFratty]

How many of your patients are started on empiric antibiotics before a respiratory culture is collected ⁉️🤔

How reliable are (-) resp cultures and can rapid molecular diagnostics play a role in these patients?

Insights from our lab @hartfordhosp

🔗https://t.co/xdkZPNzMgL

[Andrew Fratoni @AFratty]

Many of the newer BL/BLIs were created specifically to target and address KPC - we summarized their utility against Enterobacterales and Pseuds beyond KPCs in this review! Stay tuned for more organisms in Part 2 🦠🧫

[Clinical Infectious Diseases @CIDJournal]

Non-KPC Attributes of Newer β-lactamase/β-lactamase Inhibitors, Part 1: Enterobacterales and Pseudomonas aeruginosa

✅ Just Accepted
🔗 https://t.co/ZlSyRJH2to

[Andrew Fratoni @AFratty]

Hear, hear!

[...my name Keff @Fraticus]

@UConnMBB retire the damn all black unis, they’re cursed!!

[Timothy Li @drtimothyli]

Not all SOB after suspected aspiration event requires antibiotics‼️

⭐If onset is rapid (within minutes to hours) and CXR is clear
➡️consider withholding antibiotics and observe (more likely aspiration pneumonITIS rather than pneumonIA)

https://t.co/wrSoUaxvE1

[Andrew Fratoni @AFratty]

A great program! Residents have the opportunity to rotate in our CAIRD research lab and learn alongside (and often collaborate with) our ID PK/PD fellows. 🦠

[Hartford HealthCare Pharmacy Residencies @HHCPharmRes]

Are you considering a PGY2 in Infectious Diseases 🦠? We’re interviewing at PPS this week and would love to meet you!

#PharmRes #TwitteRx #ASHP23

[Duke Antimicrobial Stewardship @Duke_ASET]

For today's grand finale, we drew inspiration from Dikembe Mutombo for some new #antimicrobialstewardship strategies.

*We can neither confirm nor deny that antimicrobial stewardship will save you 15% on car insurance.*

#USAAW23 #WAAW2023 #WAAW

[Andrew Fratoni @AFratty]

Our Center @hartfordhosp is excited to be playing an integral role in this international collaboration with @CARB_X and others on this important initiative of standardizing the in vivo pneumonia model to test small molecule antibiotics! 🦠🧫
https://t.co/fIF6tLrtIB

[Andrew Fratoni @AFratty]

Looking forward to this webinar from CAIRD’s very own @PK_asempa_PD 🤩

[SIDP @SIDPharm]

Register today for a free live CE webinar on Tuesday, November 14th, 2023, 12:00 pm – 1:00 pm CT/1:00 pm – 2:00pm ET with Barbara Santevecchi, PharmD, BCPS, BCIDP and Tomefa Asempa PharmD! 1.0 hours of ACPE credit available 💻🦠

Register at: https://t.co/OxQGw2RA6I