Journal of Aging Science

Aging Science Journal considers articles in the following areas: physiology, biochemistry, molecular biology, studies related to aging specific genes

[Journal of Aging Science @Agingscience22]

Bone is a dynamic tissue that continually remodels and adapts throughout one's life. However, with aging, #age-related diseases, sedentary lifestyle, diet, and genetics all affect bone health. One of the most well-known aspects of #aging bone is a reduction in bone density.

[Journal of Aging Science @Agingscience22]

•Cellular composition of the bone marrow (BM) compartment.
•HSC self-renewal, differentiation and aging.
•MSC lineage cells during aging.
•HSC and MSC interaction in the bone marrow.
•Molecular mechanism underlying skeletal aging.
#Agingscience

[Journal of Aging Science @Agingscience22]

#Psoriasis is a frequently misunderstood condition that is associated with significant stigma. Media portrayals of skin disorders can influence public beliefs about those disorders.

[Journal of Aging Science @Agingscience22]

#Psoriasis is a chronic inflammatory dermatological condition that currently affects approximately 125 million people worldwide. It is characterized by epidermal cell hyperproliferation, aberrant differentiation of keratinocytes, and infiltration of dermis and epidermis.

[Journal of Aging Science @Agingscience22]

#Biological ageing impairs the functional and structural properties of cells, leading to the gradual degradation of physiological systems, diminished resilience, heightened susceptibility to diseases, and, ultimately, mortality.

[Journal of Aging Science @Agingscience22]

#Aging is an inevitable and intricate process that leads to the gradual decline of tissue and cellular functions, consequently increasing the risk of various age-related and geriatric diseases.

[Journal of Aging Science @Agingscience22]

Testosterone (T) treatment immediately following traumatic brain injury (TBI) mitigates #cognitive deficits and cellular dysfunction known to induce cellular #senescence. Whether the therapeutic window for T treatment can be extended to a subacute time post-injury.

[Journal of Aging Science @Agingscience22]

•Cellular #senescence progressively increases between one and two months after rmTBI.
•Persistent #cognitive deficits are mitigated by delayed testosterone administration.
•Delayed testosterone attenuates p16INK4a gene expression following rmTBI.

[Journal of Aging Science @Agingscience22]

Electroencephalography (EEG), as an inexpensive and widely available electrophysiological tool, is commonly used for the diagnosis of #epilepsy and can also be used to assess the neural activity and brain network function of epilepsy patients with #cognitive impairment.

[Journal of Aging Science @Agingscience22]

•Cognitive frailty represents a clinical connection between physical and cognitive decline.
•Many biomarkers of physical frailty are also essential to understand #cognitive frailty.
•Frailty modulates biomarker expression, gene and influences cognitive impairment prognosis.

[Journal of Aging Science @Agingscience22]

#Aging is associated with a significant decline in steroid sex hormone levels, which impairs metabolic regulation and negatively affects overall health. The aging-induced reduction in steroid sex hormones may lead to muscle atrophy.

[Journal of Aging Science @Agingscience22]

Steroid sex hormones, secreted by tissues including the reproductive organs, liver, kidney, brain, and skeletal muscles, play a crucial role in regulating various physiological functions such as energy metabolism and skeletal muscle hypertrophy.
#Agingscience

[Journal of Aging Science @Agingscience22]

#Cellular senescence, a characteristic feature of the aging process, is induced by diverse stressors. In recent years, glaucoma has emerged as a blinding ocular disease intricately linked to cellular senescence.

[Journal of Aging Science @Agingscience22]

Ovarian #senescence refers to the physiological process by which ovarian function progressively declines with age, ultimately leading to ovarian failure. This process is primarily characterized by a decrease in both the quality and quantity of follicles.

[Journal of Aging Science @Agingscience22]

#Telomeres are short, multi-repetitive, non-transcriptional sequences (TTAGGG) with associated binding proteins that act as a protector at the ends of chromosomes, preserving the integrity of genes.

[Journal of Aging Science @Agingscience22]

•Neuropsychiatric disorders are syndromes of accelerated aging.
•Telomere length, oxidation, and inflammation are #biomarkers of aging.
•Opposing results on telomere length, oxidation, and #inflammation in those disorders.

[Journal of Aging Science @Agingscience22]

•Proteostasis dysfunction in astrocytes may contribute to neurodegenerative diseases and #aging.
•Different #proteostasis pathways in astrocytes may impact brain function and aging differently.

[Journal of Aging Science @Agingscience22]

•miRNA profiles change in brain aging and related #Neurodegenerative Disorders (NDDs).
•miRNAs regulating autophagy offer therapy for #age-related brain diseases.
•Modulating miRNAs affecting #autophagy may help treat aging and NDDs.

[Journal of Aging Science @Agingscience22]

#Psoriasis is a persistent autoimmune disease caused by genetic, immune, and infectious factors characterized by excessive epidermal proliferation and a chronic inflammatory reaction in the dermis. #Erythema and scaling are the main clinical manifestations.

[Journal of Aging Science @Agingscience22]

#Psoriasis is a chronic recurrent inflammatory skin disease mediated by immune, genetic, and environmental factors. Numerous studies have demonstrated that the excessive consumption of certain pro-inflammatory foods, including alcohol and dairy products, can exacerbate psoriasis.