Allergy & Immunology Journal Club

Journal club for the allergy & immunology community || #AIMedEdJC || All are welcome || Next session TBD

[Allergy & Immunology Journal Club @AIMedEdJC]

Thanks all who joined in the 2022-23 @AIMedEdJC season! We’re taking a break for the summer and look forward to reuniting soon

[Allergy & Immunology Journal Club @AIMedEdJC]

#AIMedEd #AAAAI23

[FIT_AAAAI_org @FIT_AAAAI_org]

It’s time for our annual AAAAI Scavenger Hunt! Be on the lookout for the items in the next tweet while you’re in San Antonio for the AAAAI Annual Meeting:

[Paneez Khoury, MD (she/her) @KhouryMD]

A large group from the @EosinophilSoc including @EosDoc @adklion @TPongdee and others published retrospective data on biologic use in #HES. Covered during the last @AIMedEdJC #AIMedEdJC

Covered more here 👇🏾
https://t.co/4k2BfOZaTX

[Allergy & Immunology Journal Club @AIMedEdJC]

Thanks to @DrCorinneHappel for tonight's questions!

#AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

Thanks all who joined in last week's @AIMedEdJC Allergy & Immunology Journal Club!

The numbers: 142 Tweets. 17 Participants. 201,366 Impressions. April 28th 2022. More #AIMedEdJC 📊 here https://t.co/105PyU8HzU

[Allergy & Immunology Journal Club @AIMedEdJC]

@somewheresy @DrCorinneHappel @TitanOfTryptase Thanks for sharing your experience with us. Hearing firsthand accounts of how a person was diagnosed is a helpful way for all of us to learn. #AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

Q9: With the increasing use of biologics in allergic diseases, do you think it is possible that some of the patients we are treating with biologics never meet criteria for HES because we are treating them before they would have met criteria? Why or why not?

#AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

The effects of corticosteroids can linger for a few weeks. If an eosinophilic disorder is suspected & it is safe to stop corticosteroids, an eosinophil count can be checked again after a few weeks to see if there is an elevated baseline level.

#AIMedEd #AIMedEdJC #eosinophil I

[Allergy & Immunology Journal Club @AIMedEdJC]

Thanks @somewheresy for the great teaching point!

Eosinophil counts quickly drop (often to zero) after oral/iv corticosteroids. Do NOT use a normal eosinophil count to rule out eosinophilic disease without verifying a person was not on corticosteroids.

#AIMedEdJC #MedTwitter

[Allergy & Immunology Journal Club @AIMedEdJC]

We encourage asynchronous discussion to continue through Saturday, May 30th! Search the hashtag #AIMedEdJC to find questions posted last night and to jump in the conversation.

#eosinophils #allergy #immunology #AIMedEd #biologics

[Allergy & Immunology Journal Club @AIMedEdJC]

Thanks @JACIInPractice for providing open access to this month's #AIMedEdJC discussion article (link below)!

An International, Retrospective Study of Off-Label Biologic Use in the Treatment of Hypereosinophilic Syndromes https://t.co/Q5wveB7maX

@KhouryMD @EosDoc #eosinophil

[Allergy & Immunology Journal Club @AIMedEdJC]

Thanks for bringing this up, @karenrobbinsmd and thanks for the initial post, @winder_gill!

Great article to take a look at👇 relevant to this week’s #AIMedEdJC topic

[Karen Robbins, MD @karenrobbinsmd]

@winder_gill @AIMedEdJC I think there’s other data out there to support this….am recalling a @ckeet @aolayink article where amongst publicly insured individuals, “White patients accounted for a disproportionate amount of biologic treatment” #AIMedEdJC

https://t.co/Avb3vo4A5s

[Peter Olbrich @petolb_huvr]

@AIMedEdJC For the inborn error of immunity part please consider having a look on our recent review
#AImedEdJC
@JACIInPractice
https://t.co/vWJHRadfpK

[Allergy & Immunology Journal Club @AIMedEdJC]

@PAallergy Thanks so much for sharing your experience, @PAallergy!

[Allergy & Immunology Journal Club @AIMedEdJC]

Please take a moment to introduce yourself & to state any relevant conflicts of interest.

If you have no conflicts, please state “No COI”.

Even if you are joining later in the evening or asynchronously, we encourage & appreciate introductions.

#AIMedEdJC

[Hippocrates @md_hippocrates]

@AIMedEdJC Don’t forget new drugs recently #AIMedEdJC

[Hippocrates @md_hippocrates]

Agree and I have had the opposite occur….re check and AeC is markedly elevated #AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

Great point @winder_gill! The differential for eosinophilia is huge. Allergist-immunologists are always happy to help but also appreciate if you are also considering non-allergic causes 😀

#AIMedEdJC

[Dr. Winder Gill @winder_gill]

@AIMedEdJC I think there is a larger 'takehome' message not just for us, but for #primarycare and those involved with our patients - We often see eosinophilia on labwork, and yes, it can be associated with atopic disorders, but please consider the differentials! #AIMedEdJc @AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

Do you appreciate @AIMedEdJC journal clubs?

Would you like to get involved in the planning process or to lead a future journal club?

We welcome fresh energy & ideas!

Please reach out to @DrCorinneHappel for more info.

#AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

Save the date: Our next journal club is tentatively scheduled for Thursday, May 26th at 9:00 PM EST.

Hope to see you there!

#AIMedEdJC

[Allergy & Immunology Journal Club @AIMedEdJC]

Particular thanks to author @KhouryMD for joining in tonight's discussion! We really appreciated having your expertise.

#AIMedEdJC

[Paneez Khoury, MD (she/her) @KhouryMD]

@shaunah07 @PAallergy @AIMedEdJC If you can make the eos go down some with skin care...then more likely AD associated eosinophilia. If no matter what you do to the skin eos remain elevated and refractory skin dz then probably other way around. No easy answer but clinical judgement #AIMedEdJC