Alchemist Ledger

A running account of what works - what doesn't - and the research to back it up 🏴‍☠️

[Alchemist Ledger @AlchemistLedger]

@barstoolsports Don’t love that it’s on Paramount+ and behind a paywall. The American people paid (taxes) for the lawn on which this event is held and presumably some part of this event. Watching it should be a right of the American people.

[Alchemist Ledger @AlchemistLedger]

Sunday morning. No pins. No protocol. Just coffee and thinking.

The goal was never to live longer. The goal is to be sharp, strong, and present for the next 40 years.

Everything else — the pins, the data, the protocols — is just engineering toward that.

[Alchemist Ledger @AlchemistLedger]

Week 3 focus: blood draw scheduled — comprehensive panel + hormones. First real objective data on whether the protocol is moving the needle where it matters. Will post results.

[Alchemist Ledger @AlchemistLedger]

HRV: 33 → 39. Trending right. Target is 50+. This is a 6-week game, not a 2-week game. The trend matters more than the number right now.

[Alchemist Ledger @AlchemistLedger]

Training: all CrossFit sessions completed. Recovery between sessions faster than Week 1. Finished the CrossFit Open (ended Mar 17) without modifying a single movement at 40.

[Alchemist Ledger @AlchemistLedger]

Running the Backland Games while competing as a Masters athlete is a specific kind of motivation.

You can't cut corners on recovery when you're facing the athletes at your own event.

Ready to build this kind of protocol? https://t.co/leANiAAJHs

[Alchemist Ledger @AlchemistLedger]

Week 2 of documented protocol. No hacks, no shortcuts.

M/W/F: SS-31 + Glow Stack + Enclomiphene
Daily: Sermorelin (bedtime) + Glutathione
Weekends: off

Everything logged. Nothing improvised.

This is what separates optimization from supplementation.

[Alchemist Ledger @AlchemistLedger]

In the context of my stack: GSH protects NAD+ from oxidative degradation and reduces the oxidative load that damages cardiolipin. It's not a standalone — it's a force multiplier for everything else. (For research purposes only)

[Alchemist Ledger @AlchemistLedger]

Glutathione is the master antioxidant. Your cells produce it naturally — it neutralizes reactive oxygen species, recycles Vitamins C and E, and drives Phase II liver detox.

After 35, endogenous production drops significantly.

[Alchemist Ledger @AlchemistLedger]

Oral GSH has poor bioavailability. A troche (sublingual/buccal absorption) bypasses first-pass metabolism — blood levels are meaningfully higher than capsule GSH.

If you're taking GSH capsules, you're mostly getting expensive urine.

[Alchemist Ledger @AlchemistLedger]

Week 2 data so far:
• HRV: 33 → 38. Trending.
• Sleep: deeper, less fragmented.
• Energy: stable without caffeine spikes.
• Recovery between sessions: noticeably faster.

None of this is dramatic. That's the point. Compounding works quietly.

[Alchemist Ledger @AlchemistLedger]

My levels before: low-normal, symptomatic. Optimizing mitochondria while leaving the hormonal foundation compromised is like tuning an engine with bad fuel.

At 40, this is table stakes.

[Alchemist Ledger @AlchemistLedger]

TRT replaces testosterone. Your pituitary reads the exogenous T, stops signaling, and your testes atrophy from disuse. Fertility drops. You're on it for life.

Enclomiphene does the opposite.

[Alchemist Ledger @AlchemistLedger]

It's a selective estrogen receptor modulator (SERM). Blocks estrogen feedback at the hypothalamus → pituitary releases more LH and FSH → your testes produce more T naturally. Axis preserved. (For research purposes only)

[Alchemist Ledger @AlchemistLedger]

Rest day from pins. Sermorelin at bedtime only.

At 25, rest days felt like lost days. At 40, rest days are where the adaptation happens.

The ego says train harder. The data says recover smarter.

I'm going with the data.

[Alchemist Ledger @AlchemistLedger]

Wednesday class at CrossFit Backland. Programming hit exactly what I needed — aerobic capacity work.

Recovery is the difference between training and adapting. That's what the whole protocol is built around.

→ https://t.co/iTtkPZRdCp if you want this applied to you.

[Alchemist Ledger @AlchemistLedger]

Third pin day. Same compounds, same doses, same time.

The hardest part of a protocol isn't starting. It's not changing variables before you have data.

4 weeks minimum before I adjust anything. Right now I'm building the baseline.

[Alchemist Ledger @AlchemistLedger]

Combined: tissue repair, inflammatory control, mitochondrial support, gene expression optimization. All subQ, 20 units, rotating sites M/W/F.

Full protocol at https://t.co/leANiAAJHs

[Alchemist Ledger @AlchemistLedger]

BPC-157: Just passed its first human safety trial in 2025 — 10mg and 20mg IV, zero adverse events after 100+ animal studies. Anti-inflammatory, angiogenic, GI repair. The "no human data" crowd needs a new argument.

[Alchemist Ledger @AlchemistLedger]

GHK-Cu modulates 4,000+ genes. Primary targets: SIRT1 and STAT3 — the same pathways activated by caloric restriction. I get the longevity signal without starving during CrossFit season. (For research purposes only)